Research, Mentoring & Dissemination for PTSD Intervention in Acute Care Settings

研究、指导

• 批准号: 8670770
• 负责人: DOUGLAS F ZATZICK
• 金额: $ 17.01万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-01 至 2016-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8670770
• 关键词: Acute; Address; Adolescent; Adult; American; Applications Grants; Area; Caring; Child; Chronic; Clinical; Clinical Research; Clinical Trials; Comorbidity; Consultations; Data; Databases; Development; Effectiveness; Emergency medical service; Epidemiologic Studies; Funding; Goals; Grant; Health Services Research; Injury; Intervention; Investigation; Knowledge; Longitudinal Studies; Manuscripts; Maternal and Child Health; Medical; Mental Health; Mentors; Mentorship; Mid-Career Clinical Scientist Award (K24); Modeling; Modification; National Institute of Mental Health; Patient Care; Patients; Post-Traumatic Stress Disorders; Prevention; Principal Investigator; Procedures; Protocols documentation; Provider; Public Health; Quality of Care; Randomized Clinical Trials; Readiness; Research; Research Methodology; Research Personnel; Research Priority; Research Project Grants; Risk; Services; Severities; Strategic Planning; Supervision; Survivors; Symptoms; Training; Trauma; United States; United States Health Resources and Services Administration; United States National Institutes of Health; Violence; Work; Youth; career development; clinical epidemiology; collaborative care; contextual factors; design; dissemination research; ethnic minority population; experience; high risk behavior; implementation research; improved; indexing; injured; innovation; novel; patient oriented; patient oriented research; pediatric trauma; programs; research study; screening; screening and brief intervention; skills; trauma centers

DESCRIPTION (provided by applicant): The overarching goal of the K24 award is to improve the quality of care for injured trauma survivors with PTSD who initially present for treatment to acute care medical settings. The specific aims of the K24 application are to develop screening and intervention procedures targeting PTSD and related conditions after injury for diverse youth and adults, to mentor an interdisciplinary group of trainees in the design and implementation of patient-oriented PTSD clinical investigations, and to cultivate new research skills and knowledge in the areas of child and adolescent interventions and health services research. Additionally the K24 aims to combine innovative training and investigation at the interface of clinical epidemiology and dissemination research methods in order to comprehensively consider contextual factors in the development and implementation of acute care PTSD clinical investigations. These activities build upon the candidate's current NIMH R01 funded randomized clinical trial that is evaluating the effectiveness of a stepped collaborative care intervention that targets reductions in PTSD symptoms. Trainees will be supervised in acute care clinical research settings to develop extensions of the R01 intervention for underserved ethnic minority and youth injury survivors. Specific research projects proposed in the K24 include investigations of ethnocultural diversity and PTSD, studies of the associations between adolescent injury and the development of PTSD and related co-morbidities, nationwide assessments of trauma center readiness for implementation of PTSD screening and intervention procedures, and investigations comparing indices of intervention reach and effective size in PTSD prevention trials. The K24 award will allow for orchestrated mentorship, career development activities, and novel research that will bring the acute care PTSD research program to the greater level of integration required to attain high impact, sustainable improvements in the quality of care for diverse acute care patients with PTSD. The short and long term goals outlined in the K24 application are in concert with NIMH research priorities described in NIMH Strategic Plan Objective 4 and PA-04-075, Mental Health Consequences of Violence and Trauma. These priorities include strengthening the public health impact of NIMH-supported research and longitudinal studies examining the effectiveness of early screening and intervention procedures for PTSD.

描述（由申请人提供）：K24奖项的首要目标是提高创伤后应激障碍受伤的创伤幸存者的护理质量，这些幸存者最初是在急性护理医疗机构接受治疗的。K24应用程序的具体目标是为不同的青年和成年人制定针对创伤后应激障碍和相关损伤后状况的筛查和干预程序，指导跨学科的受训人员小组设计和实施以患者为导向的创伤后应激障碍临床调查，并培养儿童和青少年干预措施和卫生服务研究领域的新研究技能和知识。此外，K24旨在将联合收割机创新培训和临床流行病学和传播研究方法的界面调查相结合，以便全面考虑急性护理PTSD临床调查的开发和实施中的背景因素。这些活动建立在候选人目前的NIMH R 01资助的随机临床试验的基础上，该试验正在评估针对减少PTSD症状的分步协作护理干预的有效性。受训者将在急诊临床研究环境中接受监督，为服务不足的少数民族和青少年伤害幸存者开发R 01干预措施的扩展。K24中提出的具体研究项目包括调查民族文化多样性和创伤后应激障碍，研究青少年伤害与创伤后应激障碍和相关并发症的发展之间的关联，全国范围内评估创伤中心实施创伤后应激障碍筛查和干预程序的准备情况，以及比较创伤后应激障碍预防试验中干预范围和有效规模指数的调查。K24奖将允许精心策划的指导，职业发展活动和新颖的研究，这将使急性护理PTSD研究计划达到更高的整合水平，以实现对不同急性护理PTSD患者的护理质量的高影响，可持续的改善。K24应用中概述的短期和长期目标与NIMH战略计划目标4和PA-04-075中描述的NIMH研究优先事项一致，暴力和创伤的心理健康后果。这些优先事项包括加强NIMH支持的研究和纵向研究的公共卫生影响，研究PTSD早期筛查和干预程序的有效性。

项目成果

Multisite investigation of traumatic brain injuries, posttraumatic stress disorder, and self-reported health and cognitive impairments.

• DOI: 10.1001/archgenpsychiatry.2010.158
• 发表时间: 2010-12
• 期刊: ARCHIVES OF GENERAL PSYCHIATRY
• 作者: Zatzick, Douglas F.;Rivara, Frederick P.;Jurkovich, Gregory J.;Hoge, Charles W.;Wang, Jin;Fan, Ming-Yu;Russo, Joan;Trusz, Sarah Geiss;Nathens, Avery;Mackenzie, Ellen J.
• 通讯作者: Mackenzie, Ellen J.

Collaborative care intervention targeting violence risk behaviors, substance use, and posttraumatic stress and depressive symptoms in injured adolescents: a randomized clinical trial.

• DOI: 10.1001/jamapediatrics.2013.4784
• 发表时间: 2014-06
• 期刊: JAMA pediatrics
• 影响因子: 26.1
• 作者: D. Zatzick;J. Russo;S. P. Lord;C. Varley;Jin Wang;L. Berliner;G. Jurkovich;L. Whiteside;Stephen S. O’Connor;F. Rivara

Toward the estimation of population impact in early posttraumatic stress disorder intervention trials.

评估早期创伤后应激障碍干预试验中的人群影响。

• DOI: 10.1002/da.21912
• 发表时间: 2012
• 期刊: Depression and anxiety
• 影响因子: 7.4
• 作者: Zatzick,Douglas

A randomized stepped care intervention trial targeting posttraumatic stress disorder for surgically hospitalized injury survivors.

• DOI: 10.1097/sla.0b013e31826bc313
• 发表时间: 2013-03
• 期刊: Annals of surgery
• 影响因子: 9
• 作者: Zatzick D;Jurkovich G;Rivara FP;Russo J;Wagner A;Wang J;Dunn C;Lord SP;Petrie M;Oʼconnor SS;Katon W
• 通讯作者: Katon W

Technology Use, Preferences, and Capacity in Injured Patients at Risk for Posttraumatic Stress Disorder.

• DOI: 10.1080/00332747.2016.1271162
• 发表时间: 2017
• 期刊: Psychiatry
• 影响因子: 2.4
• 作者: Kelly CM;Van Eaton EG;Russo JE;Kelly VC;Jurkovich GJ;Darnell DA;Whiteside LK;Wang J;Parker LE;Payne TH;Mooney SD;Bush N;Zatzick DF
• 通讯作者: Zatzick DF