Complementary Neurotoxicological Insights from Fish, Flies, Bees and Worms Symposium

来自鱼、苍蝇、蜜蜂和蠕虫研讨会的补充神经毒理学见解

• 批准号: 8986146
• 负责人: EDWARD D LEVIN
• 金额: $ 0.3万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-01 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8986146
• 关键词: Academia; Academic Medical Centers; Animal Model; Archives; Area; Bees; Behavioral; Caenorhabditis elegans; Chemicals; Clinical; Continuing Education; Development; Drosophila genus; Epidemiology; Evaluation; Exposure to; Fishes; Fostering; Funding; Future; Genetic study; Government; Heavy Metals; In Vitro; Industry; Insecta; Institutes; International; Invertebrates; Journals; Medical center; Memory; Modeling; National Institute of Environmental Health Sciences; National Toxicology Program; Nematoda; Neurotoxins; Ontario; Peer Review; Pesticides; Postdoctoral Fellow; Principal Investigator; Quebec; Research; Research Methodology; Research Personnel; Resources; Risk; Science; Scientist; Solvents; Students; Teratology; Testing; Toxic Environmental Substances; Toxic effect; Toxicant exposure; Toxicology; Travel; United States Environmental Protection Agency; Universities; Work; Writing; Zebrafish; base; fly; insight; meetings; neurobehavioral; neuromechanism; neurotoxicity; neurotoxicology; public health relevance; screening; symposium

 DESCRIPTION (provided by applicant): The purpose of the International Neurotoxicity Association (INA) is to foster the science of determining the neural mechanisms and behavioral consequences of toxicants exposure. The bi- annual meeting (the 15th) is held for all in the field to communicate their latest research findings to their colleagues for continuing education and critical evaluation and to provide a forum for discussion of the current progress and directions for the future. INA would like to conduct a symposium with its annual meeting June 27-July 1, 2015 in Montreal, Quebec entitled "Complementary Neurotoxicologically Insights from Fish, Flies, Bees, and Worms." This symposium will provide the latest information concerning the use of aquatic, insect, and nematode models as complementary models for neurobehavioral toxicology research. The speakers will include internationally renowned researchers. This symposium will provide integration of mechanistic research with animal models of neurobehavioral function. The speakers for the symposium will be Edward Levin, Duke University Medical Center, Stephanie Padilla from the US-Environmental Protection Agency and Martina Fenske from the Fraunhofer Institute and will speak about how zebrafish help with screening potential neurotoxicants; Philip Bushnell from the US-Environmental Protection Agency will speak about using drosophila for studying genetic contributions to solvent neurotoxicity; Dr. Nigel Raine from the University of Guelph in Ontario will speak about pesticide effects on memory in bees and Michael Aschner from Albert Einstein Medical Center will speak about C. elegans heavy metal neurotoxicology; Dr. Mamta Behl of the National Toxicology and National Institute of Environmental Health Sciences will give an additional talk about how non-mammalian animal models fit into neurotoxicology testing in the National Toxicology Program.. Recent breakthroughs and research challenges will be discussed so that an intelligent agenda for neurobehavioral toxicology research in the area can be devised. The audience will be scientists active in developmental neurobehavioral toxicology research. Bringing the intellectual resources and research methods of the scientists in this field to use zebrafish, insect and nematode models will greatly enhance our ability to characterize risks that may be posed by exposure to environmental toxicants. The forum will provide an opportunity for methodological and theoretical issues to be integrated in the context of each talk as well as in a discussion session. Funding is needed for travel of non-government speakers and accommodations. Importantly, for continuing progress the Principal Investigator asks for support of students and post-doctoral trainees to participate in the meeting. Special efforts will be made to increase diversity in the field through the trainee-sponsored travel to the meeting. A write-up of the symposium will be submitted to Neurotoxicology and Teratology, a leading peer-reviewed journal in the field.

 描述（由申请人提供）：国际神经毒性协会（INA）的目的是促进确定毒物暴露的神经机制和行为后果的科学。每两年举行一次的会议（第十五届）是为了让所有在该领域的人向他们的同事传达他们的最新研究成果，以进行持续教育和批判性评估，并提供一个讨论当前进展和未来方向的论坛。INA将于2015年6月27日至7月1日在魁北克蒙特利尔举行年度会议，举办题为“鱼类、苍蝇、蜜蜂和蠕虫的补充神经毒理学见解”的研讨会。“这次研讨会将提供有关使用水生动物，昆虫和线虫模型作为神经行为毒理学研究的补充模型的最新信息。演讲者将包括国际知名的研究人员。这次研讨会将提供机制研究与神经行为功能的动物模型的整合。研讨会的发言人将是杜克大学医学中心的Edward Levin，美国环境保护署的Stephanie帕迪利亚和弗劳恩霍夫研究所的Martina Fenske，他们将谈论斑马鱼如何帮助筛选潜在的神经毒素;美国环境保护署的Philip Bushnell将谈论使用果蝇研究遗传对溶剂神经毒性的贡献;安大略省圭尔夫大学的奈杰尔·雷恩博士将谈论农药对蜜蜂记忆的影响，阿尔伯特·爱因斯坦医学中心的迈克尔·阿施纳将谈论C。elegans重金属神经毒理学;国家毒理学和国家环境健康科学研究所的Mamta Behl博士将在国家毒理学计划中额外讨论非哺乳动物模型如何适应神经毒理学测试。最近的突破和研究挑战将进行讨论，以便在该地区的神经行为毒理学研究的智能议程可以设计。听众将是活跃在发育神经行为毒理学研究领域的科学家。将这一领域科学家的智力资源和研究方法用于斑马鱼、昆虫和线虫模型，将大大提高我们描述接触环境毒物可能造成的风险的能力。该论坛将提供一个机会，将方法和理论问题纳入每一个谈话的背景下，以及在一个讨论会。需要为非政府发言者的旅费和住宿提供资金。重要的是，为了继续取得进展，主要研究者要求学生和博士后学员参加会议。将作出特别努力，通过受训人员赞助的会议旅行，增加外地的多样性。研讨会的论文将提交给该领域领先的同行评议期刊《神经毒理学和畸形学》。