Complementary Neurotoxicological Insights from Fish, Flies, Bees and Worms Symposium

来自鱼、苍蝇、蜜蜂和蠕虫研讨会的补充神经毒理学见解

基本信息

批准号：
8986146
负责人：
EDWARD D LEVIN
金额：
$ 0.3万
依托单位：
DUKE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-07-01 至 2016-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8986146
关键词：
Academia Academic Medical Centers Animal Model Archives Area Bees Behavioral Caenorhabditis elegans Chemicals Clinical Continuing Education Development Drosophila genus Epidemiology Evaluation Exposure to Fishes Fostering Funding Future Genetic study Government Heavy Metals In Vitro Industry Insecta Institutes International Invertebrates Journals Medical center Memory Modeling National Institute of Environmental Health Sciences National Toxicology Program Nematoda Neurotoxins Ontario Peer Review Pesticides Postdoctoral Fellow Principal Investigator Quebec Research Research Methodology Research Personnel Resources Risk Science Scientist Solvents Students Teratology Testing Toxic Environmental Substances Toxic effect Toxicant exposure Toxicology Travel United States Environmental Protection Agency Universities Work Writing Zebrafish base fly insight meetings neurobehavioral neuromechanism neurotoxicity neurotoxicology public health relevance screening symposium

项目摘要

DESCRIPTION (provided by applicant): The purpose of the International Neurotoxicity Association (INA) is to foster the science of determining the neural mechanisms and behavioral consequences of toxicants exposure. The bi- annual meeting (the 15th) is held for all in the field to communicate their latest research findings to their colleagues for continuing education and critical evaluation and to provide a forum for discussion of the current progress and directions for the future. INA would like to conduct a symposium with its annual meeting June 27-July 1, 2015 in Montreal, Quebec entitled "Complementary Neurotoxicologically Insights from Fish, Flies, Bees, and Worms." This symposium will provide the latest information concerning the use of aquatic, insect, and nematode models as complementary models for neurobehavioral toxicology research. The speakers will include internationally renowned researchers. This symposium will provide integration of mechanistic research with animal models of neurobehavioral function. The speakers for the symposium will be Edward Levin, Duke University Medical Center, Stephanie Padilla from the US-Environmental Protection Agency and Martina Fenske from the Fraunhofer Institute and will speak about how zebrafish help with screening potential neurotoxicants; Philip Bushnell from the US-Environmental Protection Agency will speak about using drosophila for studying genetic contributions to solvent neurotoxicity; Dr. Nigel Raine from the University of Guelph in Ontario will speak about pesticide effects on memory in bees and Michael Aschner from Albert Einstein Medical Center will speak about C. elegans heavy metal neurotoxicology; Dr. Mamta Behl of the National Toxicology and National Institute of Environmental Health Sciences will give an additional talk about how non-mammalian animal models fit into neurotoxicology testing in the National Toxicology Program.. Recent breakthroughs and research challenges will be discussed so that an intelligent agenda for neurobehavioral toxicology research in the area can be devised. The audience will be scientists active in developmental neurobehavioral toxicology research. Bringing the intellectual resources and research methods of the scientists in this field to use zebrafish, insect and nematode models will greatly enhance our ability to characterize risks that may be posed by exposure to environmental toxicants. The forum will provide an opportunity for methodological and theoretical issues to be integrated in the context of each talk as well as in a discussion session. Funding is needed for travel of non-government speakers and accommodations. Importantly, for continuing progress the Principal Investigator asks for support of students and post-doctoral trainees to participate in the meeting. Special efforts will be made to increase diversity in the field through the trainee-sponsored travel to the meeting. A write-up of the symposium will be submitted to Neurotoxicology and Teratology, a leading peer-reviewed journal in the field.

描述（应用程序提供）：国际神经毒性协会（INA）的目的是培养确定有毒物质暴露的神经机制和行为后果的科学。两年一次的会议（第15届会议）是为该领域的所有人举行的，以将其最新的研究结果传达给同事继续教育和批判性评估，并为讨论当前的进步和未来方向提供论坛。 INA想在2015年6月27日至7月1日在蒙特利尔举行的年度会议举办一场研讨会，名为“来自鱼类，苍蝇，蜜蜂和蠕虫的补充神经毒理学见解”。该研讨会将提供有关使用水生，昆虫和线虫模型作为神经行为毒理学研究的完整模型的最新信息。演讲者将包括国际知名的研究人员。该研讨会将提供机械研究与神经行为功能的动物模型的整合。研讨会的发言人将是爱德华·莱文，杜克大学医学中心，来自弗劳恩霍夫研究所的美国环境保护局的斯蒂芬妮·帕迪拉和玛蒂娜·芬斯克，并将谈论斑马鱼如何帮助筛选潜在的神经毒素；来自美国环境保护局的菲利普·布什内尔（Philip Bushnell）将谈论使用Dropophila研究遗传贡献的遗传贡献；安大略省圭尔夫大学的奈杰尔·雷恩（Nigel Raine）将谈论蜜蜂记忆的农药影响，阿尔伯特·爱因斯坦医学中心的迈克尔·阿斯纳（Michael Aschner）将谈论秀丽隐杆线虫重金属神经毒理学；国家毒理学和国家环境健康科学研究所的Mamta Behl博士将为非哺乳动物动物模型如何适合于国家毒理学计划中的神经毒理学测试。.最近的突破性和研究挑战将在该领域进行神经性毒理学研究。观众将是积极发展神经行为毒理学研究的科学家。将该领域的科学家的智力资源和研究方法带入使用斑马鱼，昆虫和线虫模型将大大增强我们表征可能通过暴露于环境毒物来定位的风险的能力。该论坛将为方法论和理论问题提供一个机会，并在每个谈话的背景下以及在讨论会议上集成。非政府扬声器和住宿需要资金。重要的是，为了持续的进展，首席研究人员要求支持学生和博士后学员参加会议。通过学员赞助的会议旅行，将做出特别的努力，以增加现场的多样性。研讨会的文章将提交给神经毒理学和畸形学，这是该领域领先的同行评审期刊。