Measuring and Improving Colonoscopy Quality Using Natural Language Processing

描述（由申请人提供）：结肠镜检查是美国筛查结直肠癌的主要方法。然而，它在筛选中的有效性受到性能变化的限制。例如，医生在结肠镜检查中发现腺瘤这种癌症前体的比率在不同医生之间相差三倍。由腺瘤检出率低的医生进行结肠镜检查的患者随后患结直肠癌的风险较高。我们的建议以测量、理解和提高结肠镜检查质量为中心。这项工作的主要创新是使用自然语言处理（NLP）来衡量结肠镜检查的质量。我们开发并验证了第一个基于NLP的计算机软件应用程序（C-QUAL），用于分析结肠镜检查和相关病理报告。我们的主要质量指标是腺瘤检出率，因为它是一种常见的、有效的与结直肠癌发病率相关的指标。然而，我们也使用了一些次要的质量度量。我们将C-QUAL应用于同一医疗系统的近25,000份结肠镜检查报告，发现医生在质量指标上的表现存在很大差异。在先前工作的基础上，我们的目标是使用C-QUAL在美国的一系列实践环境中测量结肠镜检查质量，了解导致结肠镜检查质量变化的原因，并提高结肠镜检查质量。在目标1中，我们建议使用C-QUAL工具来衡量4个不同医疗保健系统的绩效。这将是对腺瘤检出率变化的最大评估之一，将跨越不同的地理区域、支付系统和实践环境。在目标2中，我们试图理解为什么存在质量差异。我们将调查4个医疗保健系统的提供者，了解可能影响质量的因素。我们将把这些调查结果与Aim 1中评估的腺瘤检出率联系起来，并寻找关键关联。假设，但没有证明，向医生提供关于结肠镜检查质量的反馈将改善护理。在目标3中，我们评估对医生的反馈是否确实推动了质量的提高，并在目标2的基础上，探索哪种类型的医生可能会对反馈做出反应。我们的建议是第一个使用这种创新的方法来衡量结肠镜检查质量，并使用质量分数来减少结肠镜检查性能的变化。总的来说，这三个目标的结果与NCI对提高结直肠癌筛查质量的关注是一致的。

DESCRIPTION (provided by applicant): Colonoscopy is the predominant method for screening for colorectal cancer in the US. Yet, its effectiveness in screening is limited by variation in performance. For example, the rate at which physicians detect cancer precursors called adenomas during a colonoscopy has been shown to vary three-fold from one physician to another. A patient whose colonoscopy is performed by a physician with a low adenoma detection rate has a higher risk of subsequent colorectal cancer. Our proposal centers on measuring, understanding, and improving colonoscopy quality. The major innovation of this work is to use natural language processing (NLP) to measure the quality of colonoscopy. NLP is a field of computer science in which a computer is trained to "read" text to identify relevant data We developed and validated the first NLP-based computer software application (C-QUAL) that analyzes colonoscopy and associated pathology reports. Our primary quality measure is adenoma detection rate because it is a common, validated measure that is linked to colorectal cancer incidence. However, we also use a number of secondary quality measures. We applied C-QUAL to almost 25,000 colonoscopy reports in one health system and found large variation in physician's performance on the quality measures. Building on this prior work, our goal is to use C-QUAL to measure colonoscopy quality across a spectrum of US practice environments, to understand what drives variation in colonoscopy quality, and to improve colonoscopy quality. In Aim 1, we propose to use the C-QUAL tool to measure performance in 4 diverse health care systems. This will be one of the largest assessments of the variation in adenoma detection rates and will span different geographic regions, payment systems, and practice settings. In Aim 2, we seek to understand why there is variation in quality. We will survey providers at the 4 health care systems about factors that might affect quality. We will link those survey results to the adenoma detection rates assessed in Aim 1 and look for key associations. It is assumed, but not proven, that providing feedback to physicians on colonoscopy quality will improve care. In Aim 3, we assess whether feedback to physicians does drive quality improvement and, building on Aim 2, explore which types of physicians may respond to feedback. Our proposal is the first to use this innovative method to measure colonoscopy quality and to use the quality scores to decrease the variation in colonoscopy performance. Together the results of the 3 aims are consistent with the NCI's focus on improving the quality of colorectal cancer screening.