A wearable asthma trigger monitoring system with integrated physiological monitor

具有集成生理监测器的可穿戴式哮喘触发监测系统

• 批准号: 9076017
• 负责人: Alicia Esperanza Meuret
• 金额: $ 196.37万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE COUNTY
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-30 至 2020-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9076017
• 关键词: Address; Adolescent; Advisory Committees; Affect; Air; Air Pollution; Algorithms; Allergens; Asthma; Awareness; Behavioral; Breathing; Carbon Dioxide; Centers for Disease Control and Prevention (U.S.); Child; Childhood Asthma; Chronic; Chronic Disease; Classification; Consumption; Data; Development; Devices; Disease; Economically Deprived Population; Elements; Emotional Stress; Engineering; Environmental Monitoring; Environmental Risk Factor; Exhalation; Exposure to; Extrinsic asthma; Family; Goals; Guidelines; Health; Heart Rate; Hypersensitivity; Hypocapnia; Individual; Individual Differences; Inflammatory; Inhalators; Laboratories; Life; Light; Measurement; Measures; Minority; Molds; Monitor; Movement; National Institute of Biomedical Imaging and Bioengineering; Neighborhoods; Particulate; Particulate Matter; Patients; Personal Satisfaction; Pharmaceutical Preparations; Pharmacological Treatment; Physical activity; Physicians; Physiologic Monitoring; Physiological; Pilot Projects; Pollen; Population; Predisposition; Prevalence; Protocols documentation; Psychologist; Pulmonology; Radar; Recruitment Activity; Research; Sampling; Scientist; Self Management; Side; Site; Smoke; Staging; Stream; Symptoms; System; Systems Integration; Testing; Time; United States; Validation; Weight; Work; adolescent patient; asthmatic patient; base; design; experience; light scattering; multidisciplinary; novel; patient advocacy group; pediatric patients; programs; public health relevance; pyroglyphid; response; sensor; success

 DESCRIPTION (provided by applicant): Asthma is a chronic inflammatory airway disease that leads to episodic symptom exacerbations, which extoll a substantial burden on the patients' well-being and can be life threatening if not controlled adequately. Despite progress in the pharmacological treatment of asthma, overall asthma control remains unsatisfactory. Although trigger avoidance is recognized as a key element of asthma self-management, and elaborate trigger avoidance modules have been developed and distributed, their actual implementation has had mixed success. Problems lie in the variety of potential triggers, lack of systematic monitoring of triggers, and unobtrusive physiological monitors for conditions like hypocapnia are still missing. The goal of this proposal is to develop a comprehensive monitoring system that will allow simultaneous monitoring of critical environmental triggers of asthma symptoms and/or exacerbations as well as real-time physiological status of pediatric asthma patients. This will provide patients with objective information about their momentary trigger exposure with the potential to guide personalized trigger avoidance strategies and will better inform research about the factors that underlie asthma symptoms/exacerbation in daily life. We have assembled a unique and closely knit multidisciplinary team of engineers, physicians, and health psychologists. We will also be guided by and work closely with a strong External Advisory Committee and program staff at the NIBIB at all stages of the project.