Investigation of the role of PI3-kinase in the regulation of angiogenesis

PI3激酶在血管生成调节中的作用研究

• 批准号: nhmrc : GNT1104619
• 负责人: A/Pr Quenten Schwarz
• 金额: $ 83.77万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/investigation-role-pi3-regulation-angiogenesis/1346377
• 关键词: Investigation; role; PI3; kinase; regulation

The formation of blood vessels is critical for the development of embryos, but also after birth in processes such as wound healing. However, the uncontrolled formation of new blood vessels is also a feature of many human diseases such as cancer, and eye diseases that lead to blindness in adults or in premature infants. We propose to identify new regulators of blood vessel development, in order to improve current treatment therapies for these debilitating diseases.

血管的形成对于胚胎的发育至关重要，而且在出生后的伤口愈合等过程中也是如此。然而，新血管的不受控制的形成也是许多人类疾病的特征，例如癌症和导致成人或早产儿失明的眼病。我们建议确定新的血管发育调节剂，以改善目前对这些衰弱性疾病的治疗方法。