Investigation into the roles of Ena/VASP-Like and Protein Phosphatase 4C in DNA damage repair via homologous recombination
通过同源重组研究 Ena/VASP-Like 和蛋白磷酸酶 4C 在 DNA 损伤修复中的作用
基本信息
- 批准号:nhmrc : 1093995
- 负责人:
- 金额:$ 3.81万
- 依托单位:
- 依托单位国家:澳大利亚
- 项目类别:Postgraduate Scholarships
- 财政年份:2015
- 资助国家:澳大利亚
- 起止时间:2015-01-01 至 2017-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The repair of DNA damage is a critical cellular mechanism that exists to ensure genomic stability. This project aims to investigate the role of the proteins Ena/VASP-Like and Protein Phosphatase 4C in DNA damage repair via homologous recombination. The DNA damage response pathway is an important area in the study of cancer and ageing, and the potential role of PP4C and EVL in homologous recombination needs to be investigated further.
DNA损伤修复是确保基因组稳定性的关键细胞机制。本项目旨在通过同源重组研究蛋白Ena/VASP-Like和蛋白磷酸酶4C在DNA损伤修复中的作用。DNA损伤反应通路是癌症和衰老研究的重要领域,PP4C和EVL在同源重组中的潜在作用有待进一步研究。
项目成果
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