Investigation into the roles of Arabidopsis calcium sensors in stress response and development

拟南芥钙传感器在应激反应和发育中的作用研究

• 批准号: 238887-2013
• 负责人: Snedden, Wayne
• 金额: $ 2.4万
• 依托单位: Queen's University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=594197
• 关键词: Investigation; into; roles; Arabidopsis; calcium

Plants must continually monitor their environment and respond to changes with appropriate cellular and physiological adaptations. When faced with adverse environmental stress such as pathogen attack, drought, or salinity, plants initiate specific, adaptive cellular responses which include changes in gene expression, enzyme activity, and metabolic adjustments. These responses are regulated through intricate signalling systems that help orchestrate the cell's machinery into a coordinated response that is appropriately timed and specific for the given stress. Plants use calcium ions as signalling molecules and regulators during responses to virtually all types of biotic and abiotic stress. My research focuses on understanding the unique ways in which plants cells use calcium ions and calcium binding proteins to regulate stress response and development. My lab uses a variety of molecular, genetic, and biochemical tools in our research program. This work will advance our knowledge of plant cell biology and stress physiology. This research is important to the academic, biotechnology, and agricultural communites. It provides the foundation for future applications aimed at engineering enhanced stress tolerance in Canadian crops.

植物必须持续监测它们的环境，并通过适当的细胞和生理适应来应对变化。当面临不利的环境胁迫，如病原体攻击、干旱或盐度时，植物启动特异性的适应性细胞反应，包括基因表达、酶活性和代谢调节的变化。这些反应是通过复杂的信号系统调节的，这些信号系统帮助协调细胞的机制，使其对给定的压力有适当的时间和特异性的协调反应。植物利用钙离子作为信号分子和调节剂来应对几乎所有类型的生物和非生物胁迫。我的研究重点是了解植物细胞利用钙离子和钙结合蛋白调节应激反应和发育的独特方式。我的实验室在我们的研究项目中使用各种分子、遗传和生化工具。这项工作将促进我们对植物细胞生物学和胁迫生理学的认识。这项研究对学术、生物技术和农业社区都很重要。它为未来在加拿大作物中用于工程增强抗逆性的应用提供了基础。