Investigations of mechanisms underlying autonomic cardiovascular regulation in medial temporal lobe epilepsy.

内侧颞叶癫痫自主心血管调节机制的研究。

• 批准号: nhmrc : 1054862
• 负责人: Dr Marcus Gray
• 金额: $ 20.79万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/investigations-mechanisms-underlying-lobe-epilepsy/112420
• 关键词: Investigations; mechanisms; underlying; autonomic; cardiovascular

People with epilepsy often show disturbed cardiovascular function which may increase mortality risk. This may reflect seizure related disturbances in the autonomic circuitry regulation of the cardiovascular system. We apply advanced brain imaging analysis of altered neural structure, circuit connectivity and function within medial temporal lobe and mid brain, combined with clinical assessment of autonomic function to provide important new insights into cardiac disturbances in epilepsy.

癫痫患者经常表现出心血管功能紊乱，这可能会增加死亡风险。这可能反映了心血管系统自主电路调节中与癫痫发作相关的干扰。我们应用先进的脑成像分析改变的神经结构，电路连接和功能内颞叶和中脑，结合自主神经功能的临床评估，提供重要的新见解癫痫心脏紊乱。