Novel MRI approaches to map focal cortical dysplasia in focal epilepsy

绘制局灶性癫痫局灶性皮质发育不良的新 MRI 方法

• 批准号: nhmrc : 1104933
• 负责人: Dr Marcus Gray
• 金额: $ 31.89万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/novel-mri-approaches-focal-epilepsy/662791
• 关键词: Novel; MRI; approaches; map; focal

Focal cortical dysplasia (FCD) is a common cause of focal epilepsy that is resistant to medication. When it can be identified clearly, surgical removal can cure the epilepsy but better methods of detecting and mapping FCD are required because standard imaging techniques are negative in 30% of patients. In this project, we plan to develop new MRI methods to diagnose FCD, thereby creating a new MRI-based diagnostic tool for patients with focal epilepsy who are potential surgical candidates.

局灶性皮质发育不良（FCD）是一种常见的原因局灶性癫痫是耐药。当它可以被清楚地识别时，手术切除可以治愈癫痫，但需要更好的方法来检测和映射FCD，因为标准成像技术在30%的患者中是阴性的。在这个项目中，我们计划开发新的MRI方法来诊断FCD，从而为可能接受手术的局灶性癫痫患者创建一种新的基于MRI的诊断工具。