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Distance Filtering System for Retinal Implants

视网膜植入物距离过滤系统

基本信息

批准号：
8905641
负责人：
Gislin Dagnelie
金额：
$ 29.63万
依托单位：
ADVANCED MEDICAL ELECTRONICS CORPORATION
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-09-01 至 2016-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8905641
关键词：
Activities of Daily Living Algorithms Blindness Brain Cells Clinical Trials Computer software Computers Coupled Devices Digital Signal Processing Distant Doctor of Philosophy Electric Stimulation Electrodes Electronics Elements Equipment Evaluation Eye Eyeglasses FDA approved Financial compensation Future Glass Head Image Imagery Implant Indium Institutes Laboratories Lead Letters Light Macular degeneration Medical Medical Electronics Modality Motor Movement Ocular Prosthesis Ophthalmology Optics Panthera leo Patients Performance Phase Physiologic pulse Principal Investigator Process Prosthesis Reading Recording of previous events Rehabilitation therapy Research Research Project Grants Resolution Retina Retinal Retinal Degeneration Retinitis Pigmentosa Shapes Site Small Business Technology Transfer Research Solutions Source Specialist Specific qualifier value System Techniques Technology Testing Translating Universities Visible Radiation Vision Visual Visual Perception Visual impairment Visually Impaired Persons Walking Work base blind commercialization design digital imaging ergonomics experience human subject image processing imaging system improved medical schools meetings miniaturize multidisciplinary new technology next generation novel optical imaging pattern perception professor prosthesis wearer prototype public health relevance research and development research study retina implantation retinal prosthesis stereoscopic systems research vision aid visual information

项目摘要

DESCRIPTION (provided by applicant): We propose to develop and evaluate the utility of a novel input camera system for retinal prosthetics that allows users to filter optical imagery based on distance from the observer. We call this "depth filtering", which can be accomplished with a depth sensing stereoscopic camera system. Retinal prostheses can restore partial vision to people blinded by outer retinal degenerative diseases such as Retinitis Pigmentosa (RP) or Macular Degeneration. The Argus II Retinal Prosthesis System is intended to provide electrical stimulation of the retina to elicit visual perception in blind individuals with (near) total visionloss due to retinitis pigmentosa. The implanted epiretinal array provides a 10 x 6 grid of electrodes. Electrical pulses at these 60 pixel sites stimulate the retina's remaining cells and result in the perception of patterns of light. The current spatial resolution is only 60 total pixels, but the camera systems that provide image information to the prosthesis user transmit full-resolution video information. Information in the imagery consists of all visible items within the field of vie ranging for example from nearby obstacles to far away mountain scenery. The lack of perceived spatial resolution makes it extremely difficult for prosthesis users to differentiate between important nearby elements within the scene and relatively unimportant distant elements of the scenery, or vice versa. An image capture and processing system is proposed that selectively removes elements in a viewed scene that are outside a user-set depth range. We hypothesize that system utility in important tasks such as people or object finding and mobility will be less burden some, and performance improved, by providing only relevant visual information to the wearer. The proposed project seeks to develop and experiment with distance-filtered optical imagery as an input modality to retinal implants. Two prototype systems will be specified, designed, built and evaluated in Argus II patients: In phase 1 of the proposed project the image processing will be performed by a computer external to the Argus II system. In phase 2, a more powerful version of the next-generation Argus II video processing unit, capable of performing the image processing, will be utilized. This will be coupled with a new dual camera eyeglass assembly, making the phase 2 prototype fully integrated and ready for commercialization in the next generation Argus II system, and possibly in other visual prosthesis systems and head-mounted electronic low vision aids.