Web-Based Treatment of Heavy Drinking Among Women with a History of Sexual Trauma

有性创伤史女性酗酒的网络治疗

• 批准号: 8852506
• 负责人: Cynthia A. Stappenbeck
• 金额: $ 17.05万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-06-01 至 2019-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8852506
• 关键词: Address; Aftercare; Aggressive behavior; Alcohol consumption; Anxiety; Area; Award; Behavioral; Behavioral Research; Clinical; Clinical Research; Cognitive; Data; Development; Dialectical behavior therapy; Distress; Educational workshop; Emotions; Environment; Feedback; Foundations; Frequencies; Goals; Grant; Health; Heavy Drinking; Individual; Internet; Intervention; K-Series Research Career Programs; Knowledge; Laboratory Research; Lead; Manuscripts; Mediating; Mental Depression; Mental Health; Mentors; Mentorship; Monitor; Moods; Motivation; National Institute on Alcohol Abuse and Alcoholism; Online Systems; Participant; Pattern; Phase; Post-Traumatic Stress Disorders; Procedures; Process; Protocols documentation; Public Health; Randomized; Randomized Clinical Trials; Randomized Controlled Trials; Recording of previous events; Recruitment Activity; Relapse; Reporting; Research; Research Activity; Research Personnel; Resources; Risk; Sampling; Scientist; Self Medication; Severities; Statistical Methods; Surveys; Target Populations; Technology; Testing; Therapeutic Intervention; Training; Training Activity; Trauma; Treatment Efficacy; Treatment outcome; Universities; Washington; Woman; Writing; active control; alcohol abuse therapy; alcohol intervention; alcohol research; assault; base; career; cohort; college; coping; distress tolerance; drinking; emotion regulation; experience; follow-up; handheld mobile device; innovative technologies; men; negative mood; novel; psychological distress; research study; sex; sexual assault; sexual trauma; skills; stressor; symposium; therapy development; treatment adherence; treatment effect; web site

DESCRIPTION (provided by applicant): Dr. Cynthia Stappenbeck has a strong foundation in alcohol research with an emphasis on examining the associations among alcohol use, trauma exposure, interpersonal aggression, and emotion regulation. Her long-term career goal is to build upon her previous experience conducting laboratory and experimental research to become an independent clinical scientist able to make a substantive contribution to the field of alcohol research by developing, evaluating, and widely disseminating therapeutic interventions among individuals at risk for problems associated with heavy drinking. Through her 5-year training plan and complementary research plan, the Mentored Clinical Scientist Research Career Development Award provides an opportunity for her to achieve this goal. Aims of the training plan include gaining experience conducting randomized controlled trials, continuing to develop advanced multivariate statistical skills, gaining knowledge on how to leverage technology for the administration and dissemination of therapeutic interventions, and presenting and disseminating data. These more immediate goals will be achieved through an interactive training plan comprised of direct mentorship, formal coursework, seminars, workshops, attendance at national conferences, and manuscript and grant writing. Dr. Stappenbeck's knowledge gained through the activities outlined in the training plan will be augmented by the proposed research. The goal of the research plan is to develop and empirically evaluate a web-based intervention to reduce heavy drinking among college women with a history of sexual assault who display elevated levels of psychological distress. College women with a history of sexual assault often report more heavy drinking and psychological distress than women without a history of assault. Moreover, women with assault histories often have difficulty regulating their emotions and tolerating distress which can lead to a pattern of drinking to cope distress. Trauma exposure, negative mood, and poor coping strategies have been associated with poor treatment outcomes and relapse following alcohol treatment. Incorporating distress tolerance and emotion regulation skills with an alcohol intervention may enhance treatment effects among women with a history of sexual assault by decreasing their motivation to drink to cope with depression or anxiety and by building adaptive coping strategies. Therefore, the web-based intervention will include cognitive behavioral skills for reducing alcohol consumption and incorporate emotion regulation and distress tolerance skills from Dialectical Behavior Therapy. The first phase of this research includes the initial development and continued refinement of the web-based intervention modules using an iterative process in which participant and expert feedback on intervention material is received and then an open trial is conducted to further refine the intervention and website. The second phase consists of a randomized controlled trial in which heavy drinking college women with a history of sexual assault and elevated levels of psychological distress will be recruited and randomized to receive the intervention or an assessment only control. Web-based surveys will be administered at baseline and post-treatment as well as 1- month and 6-months post-treatment in order to provide a more thorough examination of the mechanisms of change associated with the intervention. Drs. Debra Kaysen, Dennis Donovan, Melanie Harned, and David Atkins will serve as mentors on this award and Dr. William George will serve as an advisor. Collectively the mentorship team will provide expertise in the content areas, the conduct of randomized clinical trials, advanced statistical analyses, and use of technology to deliver interventions. Resources at the University of Washington provide an environment conducive to developing a career in alcohol research and gaining the skills necessary to launch a career as an independent scientist. The proposed award will provide pilot data for Dr. Stappenbeck's first R01 submission to NIAAA to more rigorously test this intervention against active controls with a larger sample and is consistent with NIH's goal of increasing and maintaining a strong cohort of investigators to address the Nation's behavioral and clinical research needs.

描述(由申请人提供)：辛西娅·斯塔彭贝克博士在酒精研究方面有很强的基础，重点研究酒精使用、创伤暴露、人际攻击和情绪调节之间的联系。她的长期职业目标是以她之前进行实验室和实验研究的经验为基础，成为一名独立的临床科学家，能够通过开发、评估和广泛传播治疗干预措施来为酒精研究领域做出实质性贡献，这些干预措施是针对与酗酒相关的问题的高危人群。通过她的5年培训计划和补充研究计划，导师临床科学家研究职业发展奖为她提供了实现这一目标的机会。培训计划的目标包括获得进行随机对照试验的经验，继续发展先进的多变量统计技能，获得关于如何利用技术管理和传播治疗干预措施的知识，以及提供和传播数据。这些更直接的目标将通过互动式培训计划实现，该计划包括直接指导、正式课程作业、研讨会、讲习班、出席国家会议以及撰写手稿和赠款。斯塔彭贝克博士通过培训计划中概述的活动获得的知识将因拟议的研究而得到加强。这项研究计划的目标是开发一种基于网络的干预措施，并对其进行实证评估，以减少有性侵病史的大学女性大量饮酒，这些女性表现出更高的心理痛苦水平。与没有性侵病史的女性相比，有性侵病史的大学女生报告的酗酒和心理困扰往往更多。此外，有性侵历史的女性往往难以控制自己的情绪，难以忍受痛苦，这可能导致一种饮酒来应对痛苦的模式。创伤暴露、消极情绪和糟糕的应对策略与不良的治疗结果和酒精治疗后的复发有关。将痛苦耐受性和情绪调节技能与酒精干预结合起来，可能会通过降低女性饮酒动机来应对抑郁或焦虑，并通过建立适应性应对策略来增强对有性侵病史的女性的治疗效果。因此，基于网络的干预将包括减少饮酒的认知行为技能，并纳入辩证行为疗法的情绪调节和承受痛苦的技能。这项研究的第一阶段包括利用迭代过程初步开发和继续完善基于网络的干预模块，在迭代过程中，接收参与者和专家对干预材料的反馈，然后进行公开试验，以进一步完善干预和网站。第二阶段包括一项随机对照试验，在该试验中，将招募有性侵病史和心理困扰水平升高的酗酒女大学生，并随机接受干预或仅接受评估的对照。将在基线和治疗后以及治疗后1个月和6个月进行网上调查，以便更彻底地审查与干预有关的变化机制。黛布拉·凯森博士、丹尼斯·多诺万博士、梅勒妮·哈内德博士和大卫·阿特金斯博士将担任该奖项的导师，威廉·乔治博士将担任顾问。指导团队将共同提供内容领域的专业知识、进行随机临床试验、先进的统计分析以及使用技术提供干预措施。华盛顿大学的资源提供了一个有利于发展酒精研究事业的环境，并获得了作为一名独立科学家开始职业生涯所需的技能。拟议的奖励将为斯塔彭贝克博士向NIAAA提交的第一份R01报告提供试点数据，以便通过更大的样本更严格地测试这种针对主动控制的干预措施，并与NIH增加和保持强大的研究人员队列的目标一致，以满足国家的行为和临床研究需求。