Understanding somatic mutation in plants: new methods, new software, new data.

了解植物体细胞突变：新方法、新软件、新数据。

• 批准号: FT140100843
• 负责人: Prof Robert Lanfear
• 金额: $ 53.02万
• 依托单位: The Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: ARC Future Fellowships
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-09-08 至 2018-09-07
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FT140100843
• 关键词: Understanding; somatic; mutation; plants; new

Somatic mutations accumulate as plants grow, affecting everything from short-term ecological interactions to long-term evolutionary dynamics. These mutations have important consequences for plant industry and conservation, but because they are so hard to measure almost nothing is known about them. This project aims to develop new methods and software to detect, analyse, and compare the genome-wide history of somatic mutation in individual plants, providing an unprecedented level of detail into an important but understudied source of biological variation. By applying these methods to an iconic experimental population, This project aims to provide the first insights into the genome-wide causes and consequences of somatic mutation in plants.

体细胞突变随着植物的生长而积累，影响从短期生态相互作用到长期进化动力学的一切。这些突变对植物工业和保护有着重要的影响，但由于它们很难测量，人们对它们几乎一无所知。该项目旨在开发新的方法和软件来检测、分析和比较单个植物体细胞突变的全基因组历史，为生物变异的重要但尚未得到充分研究的来源提供前所未有的详细信息。通过将这些方法应用于一个标志性的实验群体，该项目旨在首次深入了解植物体细胞突变的全基因组原因和后果。