Agricultural intervention for food security and HIV healthoutcomes in Kenya
肯尼亚粮食安全和艾滋病毒健康结果的农业干预
基本信息
- 批准号:8922460
- 负责人:
- 金额:$ 104万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2015
- 资助国家:美国
- 起止时间:2015-05-07 至 2020-04-30
- 项目状态:已结题
- 来源:
- 关键词:AIDS/HIV problemAccountingAddressAdultAfrica South of the SaharaAgricultureBehavioralCD4 Lymphocyte CountCaringCharacteristicsChildClinicClinicalComorbidityCost Effectiveness AnalysisCountryDataDevelopmentDietDiseaseEducationEffectiveness of InterventionsEnrollmentEpidemicEvaluationFamily SizesFarming environmentFemaleFertilizersFoodFundingFutureGenderGoalsGrowthHIVHealthHealth StatusHealth care facilityHip region structureHospitalizationHouseholdHumanHungerImmunologicsIncomeIndividualInternationalInterventionIntervention TrialKenyaLeadLifeMediator of activation proteinMental DepressionMental HealthMethodsModelingMorbidity - disease rateNational Institute of Mental HealthNutritionalNutritional statusOccupational activity of managing financesOutcomeParticipantPathway interactionsPatientsPesticidesPilot ProjectsPopulationPovertyProcessPumpRandomizedRandomized Controlled TrialsRiskRouteRural PopulationSamplingSeedsStagingSupport GroupsTechnologyTestingTheoretical modelTreatment FailureUnited States National Institutes of HealthViral Load resultWaterWorkantiretroviral therapyarmbasebehavioral outcomecombatcostcost effectivecost effectivenessdisability-adjusted life yearseconomic indicatorempowermentexperiencefarmerfollow-upfood securityhealth economicshigh riskimprovedintervention effectmortalityphysical conditioningpreventprimary outcomeresponsescale upsecondary outcometherapy adherencetransmission process
项目摘要
DESCRIPTION (provided by applicant): Despite major advances in care and treatment for those living with HIV, morbidity and mortality among people living with HIV/AIDS (PLHIV) remain unacceptably high in sub-Saharan Africa (SSA), largely due to the parallel challenges of poverty and food insecurity. Food insecurity and poverty contribute to higher morbidity and mortality among PLHIV, and there has been increasing international recognition of the need to address these factors for a successful global response to the HIV epidemic. Yet, to date there have been few studies to systematically evaluate the impact and cost-effectiveness of promising food security interventions on health outcomes among PLHIV. To address these gaps, together with KickStart, a non-governmental organization based in SSA, we have developed a multisectoral intervention in Nyanza Region, Kenya that includes: a) a microfinance loan (~$175) for purchasing agricultural implements and commodities; b) agricultural implements to be purchased with the loan including a human-powered water pump, seeds, fertilizers and pesticides; and c) education in financial management and sustainable farming practices. We successfully completed an NIH- funded pilot intervention trial that showed that the intervention was feasible, acceptable and may improve HIV- related health. We now plan to conduct a cluster randomized controlled trial (RCT) of this intervention with the following specific aims: Ai 1: To determine the impact of a multisectoral agricultural intervention among HIV- infected farmers on ART on HIV clinical outcomes. We hypothesize that the intervention will lead to improved viral load suppression (primary outcome) and decreased HIV-related morbidity in the intervention arm
描述(由申请人提供):尽管在艾滋病毒感染者的护理和治疗方面取得了重大进展,但在撒哈拉以南非洲(SSA),艾滋病毒/艾滋病感染者(PLHIV)的发病率和死亡率仍然高得令人无法接受,这主要是由于贫困和粮食不安全的并行挑战。粮食不安全和贫穷是艾滋病毒感染者发病率和死亡率较高的原因,国际社会日益认识到,要成功地在全球应对艾滋病毒流行病,就必须解决这些因素。然而,迄今为止,很少有研究系统地评估有希望的粮食安全干预措施对艾滋病毒感染者健康结果的影响和成本效益。为了弥补这些差距,我们与设在撒南非洲的非政府组织KickStart一起,在肯尼亚尼扬扎地区制定了多部门干预措施,其中包括:a)小额贷款(约175美元),用于购买农具和商品; B)用贷款购买农具,包括人力水泵、种子、化肥和杀虫剂;以及c)财务管理和可持续耕作方法的教育。我们成功地完成了一项由美国国立卫生研究院资助的试点干预试验,该试验表明该干预措施是可行的,可接受的,并可能改善艾滋病毒相关的健康。我们现在计划对这种干预进行一项随机对照试验(RCT),具体目标如下:Ai 1:确定艾滋病毒感染农民中多部门农业干预对ART对艾滋病毒临床结果的影响。我们假设,干预将导致改善病毒载量抑制(主要结局)和降低干预组的HIV相关发病率
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
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CRAIG R COHEN其他文献
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{{ truncateString('CRAIG R COHEN', 18)}}的其他基金
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- 资助金额:
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10406532 - 财政年份:2021
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10253430 - 财政年份:2021
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Phase 2 placebo-controlled randomized trial of LACTIN-V (Lactobacillus crispatus CTV-05) among women at high risk of HIV acquisition in Durban, South Africa
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10372975 - 财政年份:2019
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$ 104万 - 项目类别:
Phase 2 placebo-controlled randomized trial of LACTIN-V (Lactobacillus crispatus CTV-05) among women at high risk of HIV acquisition in Durban, South Africa
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- 批准号:
10617632 - 财政年份:2019
- 资助金额:
$ 104万 - 项目类别:
Phase 2 placebo-controlled randomized trial of LACTIN-V (Lactobacillus crispatus CTV-05) among women at high risk of HIV acquisition in Durban, South Africa
在南非德班感染艾滋病毒高危女性中进行的 LACTIN-V(卷曲乳杆菌 CTV-05)的 2 期安慰剂对照随机试验
- 批准号:
10488446 - 财政年份:2019
- 资助金额:
$ 104万 - 项目类别:
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- 批准号:
9277256 - 财政年份:2016
- 资助金额:
$ 104万 - 项目类别:
Agricultural intervention for food security and HIV healthoutcomes in Kenya
肯尼亚粮食安全和艾滋病毒健康结果的农业干预
- 批准号:
9064868 - 财政年份:2015
- 资助金额:
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