肯尼亚粮食安全和艾滋病毒健康结果的农业干预-猫眼课题宝

肯尼亚粮食安全和艾滋病毒健康结果的农业干预

批准号：

9064868

负责人：

CRAIG R COHEN

金额：

$96.84万

依托单位：

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO

依托单位国家：

美国

项目类别：

财政年份：

2015

资助国家：

美国

项目状态：

已结题

起止时间：

2015-05-07 至 2020-04-30

来源：

https://reporter.nih.gov/project-details/9064868

关键词：

AIDS/HIV problem Accounting Address Adult Africa South of the Sahara Agriculture Behavioral CD4 Lymphocyte Count Caring Characteristics Child Clinic Clinical Comorbidity Cost Effectiveness Analysis Country Data Development Diet Disease Education Effectiveness of Interventions Enrollment Epidemic Evaluation Family Sizes Farming environment Female Fertilizers Food Funding Future Gender Goals Growth HIV Health Health Status Health care facility Hip region structure Hospitalization Household Human Hunger Immunologics Income Individual International Intervention Intervention Trial Kenya Lead Life Mediator of activation protein Mental Depression Mental Health Methods Modeling Morbidity - disease rate National Institute of Mental Health Nutritional Nutritional status Occupational activity of managing finances Outcome Participant Pathway interactions Patients Pesticides Pilot Projects Population Poverty Process Pump Randomized Randomized Controlled Trials Risk Route Rural Population Sampling Seeds Staging Support Groups Technology Testing Theoretical model Treatment Failure United States National Institutes of Health Viral Load result Water Work antiretroviral therapy arm base behavioral outcome combat cost cost effective cost effectiveness disability-adjusted life years economic indicator empowerment experience farmer follow-up food security health economics high risk improved improved outcome intervention effect mortality physical conditioning prevent primary outcome response scale up secondary outcome therapy adherence transmission process

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DESCRIPTION (provided by applicant): Despite major advances in care and treatment for those living with HIV, morbidity and mortality among people living with HIV/AIDS (PLHIV) remain unacceptably high in sub-Saharan Africa (SSA), largely due to the parallel challenges of poverty and food insecurity. Food insecurity and poverty contribute to higher morbidity and mortality among PLHIV, and there has been increasing international recognition of the need to address these factors for a successful global response to the HIV epidemic. Yet, to date there have been few studies to systematically evaluate the impact and cost-effectiveness of promising food security interventions on health outcomes among PLHIV. To address these gaps, together with KickStart, a non-governmental organization based in SSA, we have developed a multisectoral intervention in Nyanza Region, Kenya that includes: a) a microfinance loan (~$175) for purchasing agricultural implements and commodities; b) agricultural implements to be purchased with the loan including a human-powered water pump, seeds, fertilizers and pesticides; and c) education in financial management and sustainable farming practices. We successfully completed an NIH- funded pilot intervention trial that showed that the intervention was feasible, acceptable and may improve HIV- related health. We now plan to conduct a cluster randomized controlled trial (RCT) of this intervention with the following specific aims: Ai 1: To determine the impact of a multisectoral agricultural intervention among HIV- infected farmers on ART on HIV clinical outcomes. We hypothesize that the intervention will lead to improved viral load suppression (primary outcome) and decreased HIV-related morbidity in the intervention arm

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