Techniplast Sealsafe Plus Mouse Rack System (LAMb)

Techniplast Sealsafe Plus 鼠标架系统 (LAMb)

• 批准号: 8951325
• 负责人: Philip S Tsao
• 金额: --
• 依托单位: VETERANS ADMIN PALO ALTO HEALTH CARE SYS
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-01-01 至 2015-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8951325
• 关键词: Air; Allergens; Ammonia; Animal Experimentation; Animal Housing; Animal Husbandry; Animal Welfare; Animals; Area; Award; Carbon Dioxide; Characteristics; Consumption; Containment; Docking; Duct (organ) structure; Dust; Ensure; Environment; Equipment; Floor; Growth; Health; Heating; House mice; Housing; Individual; Label; Length; Manufacturer Name; Mental Depression; Microprocessor; Modeling; Mus; Noise; Oxygen; Performance; Plastics; Population; Price; Research Personnel; Research Project Grants; Rodent; Safety; Side; Silicones; Stainless Steel; Stress; System; Visual; Water; Water consumption; Weight; animal colony; anxious behavior; cost; flexibility; pathogen; polysulphone; prevent; programs; public health relevance; touchscreen

 DESCRIPTION (provided by applicant): In order to maintain the health of the animal colony, principles of animal husbandry that provide an ideal environment for the animals is essential. Consistent with federal mandated practices, the requested equipment will maximize the comfort and health of the animals, minimize moisture and ammonia levels in the cages, and provide an effective barrier from possible pathogens. The requested individual ventilated caging provides an ideal microenvironment for the animal. If this request is awarded, we can house all our mice in ventilated racks, except for mice housed in our BSL-2 suite that cannot accommodate a ventilated rack. Not only will these racks enhance the husbandry of the animals, it will also allow us to expand our housing capacity by 13%, which is essential to keep up with the growth of our animal program (currently we house approximately 18,000 mice. Expanding the number of ventilated racks will enhance our abilities to ensure the welfare of the animals, as well as, provide increased flexibility to respond to the changing needs of the investigators. As the ventilated cages house more animals than standard racks, which accommodates the growing animal usage needs of our expanding animal research program. Housing rodents in ventilated racks like Sealsafe Plus will protect them from infective agents and protect the animal users from allergens and requires a high volume of air to be blown into the cages so as to provide the optimal micro-environment, thus aiming to maintain a low concentration of ammonia, carbon dioxide and a stable concentration of oxygen.

 描述（由申请人提供）： 为了保持动物群体的健康，为动物提供理想环境的畜牧业原则至关重要。根据联邦规定的做法，所要求的设备将最大限度地提高动物的舒适度和健康，最大限度地降低笼中的水分和氨水平，并提供有效的屏障，防止可能的病原体。所要求的单独通风笼舍为动物提供了理想的微环境。如果这一请求获得批准，我们可以将所有小鼠安置在通风机架中，但安置在我们的BSL-2套件中的小鼠无法容纳通风机架。这些架子不仅可以提高动物的饲养能力，还可以让我们通过以下方式扩大住房容量： 13%，这对于跟上我们动物项目的增长至关重要（目前我们大约有18，000只小鼠。增加通风架的数量将提高我们确保动物福利的能力，并提供更大的灵活性，以应对研究者不断变化的需求。由于通风笼比标准笼架容纳更多的动物，这满足了我们不断扩大的动物研究计划中不断增长的动物使用需求。将啮齿动物饲养在Sealsafe Plus等通风架上，可保护它们免受感染性病原体的侵害，并保护动物使用者免受过敏原的侵害，并需要向笼内吹入大量空气，以提供最佳的微环境，从而旨在保持低浓度的氨，二氧化碳和稳定的氧气浓度。