FASEB's "The 5th International Conference on Retinoids"

FASEB“第五届类维生素A国际会议”

• 批准号: 9993697
• 负责人: MAUREEN A KANE
• 金额: $ 1.44万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-01 至 2022-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9993697
• 关键词: Address; Alzheimer' s Disease; American; Area; Award; Biochemical; Biological Process; Biology; Clinical; Collaborations; Databases; Development; Diabetes Mellitus; Discipline; Disease; Embryonic Development; Ensure; Enzymatic Biochemistry; Funding; Goals; Health; Homeostasis; Human; Immune System Diseases; Immunity; Immunologist; Immunology; Individual; International; Malignant Neoplasms; Mediating; Metabolic Diseases; Metabolic dysfunction; Metabolism; Molecular; Molecular Immunology; Nutritional; Oral; Pathology; Pharmacology; Physiological; Postdoctoral Fellow; Process; Reporter; Reporting; Reproduction; Request for Applications; Research; Research Activity; Research Personnel; Research Project Grants; Resort; Retinoid Receptor; Retinoids; Science; Scientist; Senior Scientist; Signal Transduction; Societies; Structural Biologist; Therapeutic; Time; Training; Translational Research; Travel; Underrepresented Populations; United States National Institutes of Health; Update; Vision; Visual; Vitamin A; Woman; Work; base; bench to bedside; capsule; career; cell type; disorder prevention; equity diversity and inclusion; fundamental research; graduate student; meetings; nervous system disorder; novel; nutrition; posters; regenerative biology; skin disorder; stem cell biology; stem cells; symposium; training opportunity

PROJECT SUMMARY / ABSTRACT This NIH R13 application requests partial support for the Federation of American Societies for Experimental Biology (FASEB) 5th International Conference on Retinoids that will be held at Loews Ventana Resort, Tuscon, AZ from June 14, 2020 to June 19, 2020. The FASEB Science Research Conference on Retinoids has been held every other year since 1982 where the meeting planned for 2020 will be the 20th FASEB Science Research Conference on Retinoids. This biennial research conference has been very well attended (ranging from 100 to 200 attendees over the past 38 years) and remains the only major national and international conference committed to focus on the studies of retinoids, and to comprehensively address the broad spectrum of retinoid actions and application in an integrative manner. While the mechanisms of action and the biological functions of retinoids have been intensively studied, there is an increasing need for understanding and applying retinoids in human nutrition and diseases. Currently, a great deal of research activity is supported by the NIH (the NIH RePORTER database indicates 1666 NIH funded individual research grants involving aspects of retinoid/vitamin A biology). The main topics to be addressed include both basic and translational fronts of retinoid biology: 3 sessions on retinoid mechanisms (I, Retinoid receptors, retinoid receptor-mediated biology; II, Retinoid metabolism, homeostasis, and enzymology; III, Development, stem cell and regenerative biology); 3 sessions on retinoids and disease (I, Immune disorders and immunology; II, Signaling and metabolic dysfunction; III, Cancer and related pathologies), and 2 sessions on molecular therapeutics (I, Retinoid mechanisms and novel targets; II, Rexinoids and novel pharmacological applications). The overall goal is to bring together a group of committed investigators (senior scientists, mid-career scientists, junior scientists, postdoctoral fellows, and graduate students), who work in diverse disciplines (as biochemists, molecular biologists, nutritional scientists, cancer researchers, vision researchers, stem cell biologists, biophysicists, structural biologists, immunologists, chemists, and clinicians) to present and discuss their latest research findings that share a common focus on the retinoids. To encourage new/young investigators and trainees to attend this meeting, we plan to offer six career- oriented training sessions and six meet-the-expert sessions. To increase visibility of trainees through oral presentations, we plan twenty-four 5-min capsule reports based on posters as well as five 5-min poster award presentations. This meeting has been strongly supported by NIH in the past. The 2020 Retinoid Conference will allow young investigators and trainees to obtain much needed updates on the current state of the various branches of the field and will most certainly stimulate their careers as well as collaborations with basic scientists and clinicians. We respectfully request partial support for the 2020 FASEB Retinoid Conference to increase the attendance by under-represented and women scientists, trainees, postdoctoral fellows, and early-stage investigators to facilitate entry into this research area in order to spur interdisciplinary and translational science.

项目概要/摘要 此 NIH R13 申请请求美国实验协会联合会的部分支持 生物学 (FASEB) 第五届类视黄醇国际会议将在图森洛斯本塔纳度假村举行 AZ从2020年6月14日到2020年6月19日。FASEB类维生素A科学研究会议已举办 自 1982 年以来每隔一年举行一次，计划于 2020 年举行的会议将是第 20 届 FASEB 科学研究 类维生素A会议。这个两年一度的研究会议出席人数非常多（从 100 到 过去 38 年有 200 名与会者），仍然是唯一的大型国内和国际会议 致力于专注于类维生素A的研究，全面解决类维生素A的广谱问题 行动与应用相结合。虽然作用机制和生物学功能 类视黄醇已被深入研究，人们越来越需要了解和应用类视黄醇 人类营养与疾病。目前，大量的研究活动得到了美国国立卫生研究院（NIH）的支持。 RePORTER 数据库显示 1666 项 NIH 资助的个人研究经费涉及类维生素A/维生素方面 生物学）。讨论的主要主题包括类维生素A生物学的基础和转化前沿：3 关于类维生素A机制的会议（I，类维生素A受体，类维生素A受体介导的生物学；II，类维生素A 新陈代谢、体内平衡和酶学； III、发育、干细胞和再生生物学）； 3 节课 类维生素A与疾病（I，免疫性疾病和免疫学；II，信号传导和代谢功能障碍；III， 癌症和相关病理学），以及 2 场分子疗法课程（I，类视黄醇机制和新型 目标； II，Rexinoids 和新的药理学应用）。总体目标是聚集一群 忠诚的研究人员（高级科学家、职业中期科学家、初级科学家、博士后研究员和 研究生），在不同学科工作（如生物化学家、分子生物学家、营养科学家、 癌症研究人员、视觉研究人员、干细胞生物学家、生物物理学家、结构生物学家、免疫学家、 化学家和临床医生）展示并讨论他们共同关注的最新研究成果 类维生素A。为了鼓励新的/年轻的研究者和实习生参加这次会议，我们计划提供六种职业- 定向培训课程和六次专家见面会。通过口述提高学员的知名度 演讲中，我们计划了 24 个基于海报的 5 分钟胶囊报告以及 5 个 5 分钟海报奖 演示文稿。本次会议历来得到了NIH的大力支持。 2020 年 Retinoid 会议将 允许年轻的调查人员和受训人员获得有关各种现状的急需的最新信息 该领域的分支，肯定会刺激他们的职业生涯以及与基础科学家的合作 和临床医生。我们谨请求对 2020 年 FASEB 类视黄醇会议提供部分支持，以增加 代表性不足的女性科学家、实习生、博士后研究员和早期阶段人员的出席 促进研究人员进入这一研究领域，以促进跨学科和转化科学。