Development of LEAP for the Homeless with Alcohol Problems

为有酗酒问题的无家可归者开发 LEAP

基本信息

  • 批准号:
    8817220
  • 负责人:
  • 金额:
    $ 17.44万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2013
  • 资助国家:
    美国
  • 起止时间:
    2013-02-01 至 2016-01-31
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): Since receiving my doctorate in Cognitive and Experimental Psychology in 2003, I have been designing, conducting and publishing high-quality experimental alcohol research. Over the past few years, I have become increasingly interested in applying my alcohol research skills to addressing "real-world" clinical problems. I am therefore submitting this proposal for a K01 Mentored Career Development Award to support my burgeoning interest and independent research program in community-based, clinically focused alcohol intervention research. The K01 will facilitate my acquisition of trainin and knowledge in community and clinical theory, research and design and compliment my foundation in experimental alcohol research, which will thereby help me reach my research training goals and longer-term career objectives. The career development plan that I am proposing for the K01 includes a) obtaining training in community and clinical theory, research and practice; b) enhancing my scientific publication and research dissemination record in community-based, clinically focused alcohol intervention research; and c) honing my grant-writing skills to secure independent funding in this new area. My primary mentor, Dr. Mary Larimer, is a well-established leader in clinically focused alcohol intervention research, and my proposed team of expert collaborators and consultants is well-qualified to provide me with the supervision and support I need to work towards my career objectives and successfully complete the proposed research. Additionally, the UW research and academic environment, where the proposed career and research plans will be implemented, is internationally recognized for its collegial environment and excellence in research and academic training. Most important, my proposed research and career goals are relevant to larger public health issues, because I intend to design, implement, evaluate and disseminate alcohol-specific interventions to improve alcohol, health and quality-of-life outcomes for severely affected, costly and marginalized populations. With my strong background in alcohol research and my burgeoning interest in clinically focused and community-based interventions, I believe I am a strong candidate for this K01 award mechanism. Within the context of the proposed K01, I will be designing, implementing, evaluating, leading, and disseminating innovative and clinically significant, community-based alcohol intervention research. Specifically, I am proposing to work with a community-based agency, the Downtown Emergency Service Center (DESC), and use a CBPR paradigm to develop and evaluate a comprehensive life enhancing alcohol- management program (LEAP) to improve alcohol, health and quality-of-life outcomes for formerly chronically homeless individuals with alcohol problems. Chronically homeless individuals with alcohol problems often have co-occurring medical and psychiatric disorders, which can translate into increased public costs due to greater use of emergency medical services, criminal arrests, and incarceration. DESC uses an innovative approach, project-based housing first (HF), to provide supportive housing for this severely affected and marginalized population. In project-based HF, individuals are offered permanent, low-barrier housing without preconditions such as alcohol abstinence or treatment attendance. This approach has been associated with reduced costs and improved alcohol, health and quality-of-life outcomes. While HF approaches are associated with improved outcomes for the target population and the larger community, most residents continue to consume alcohol and report clinically significant alcohol- related problems. This population also encounters various barriers to alcohol treatment, and traditional treatment options are generally ineffective. One reason why traditional treatment may not engage this population is that its exclusive focus on abstinence neglects individuals' overall quality of life and the larger biopsychosocial context for their alcohol use. To more comprehensively and effectively address the needs of this population, I am proposing a 5-year project to develop and test the treatment effectiveness and integrity of the LEAP in improving alcohol, health and quality-of-life outcomes. This intervention will be compatible with and integrated into the low- barrier HF approach currently in place in DESC housing. Phase I will involve baseline qualitative data collection to identify potential points for intervention enhancement (year 1). Phase II will entail community-based LEAP manual development (year 2). Phase III will consist of a 12-month, nonrandomized controlled trial (NRCT) testing LEAP effectiveness compared to a project-based HF control (years 3,4). Latent growth models will be used to test LEAP effectiveness compared to IAU in improving alcohol-use, health, and quality-of-life outcomes from baseline through the 3-, 6- and 12-month follow-ups. Phase IV will comprise treatment integrity analyses, including manual adherence and competence as well as participants' treatment receipt and enactment (years 4,5). This study will build a foundation for longer- term research objectives: a multisite, cluster-randomized controlled trial of the LEAP and wider dissemination of this comprehensive, evidence-based program. In summary, my proposed career development and research plan are an excellent fit with the K01 mechanism as well as with the NIAAA mission to further scientific knowledge to improve and address public health-related research needs of our nation.
简介(申请人提供):自2003年获得认知和实验心理学博士学位以来,我一直在设计、进行和出版高质量的实验酒精研究。在过去的几年里,我越来越有兴趣将我的酒精研究技能应用于解决“现实世界”的临床问题。因此,我提交了这份关于K01导师职业发展奖的提案,以支持我对以社区为基础、以临床为重点的酒精干预研究日益增长的兴趣和独立研究计划。K01将促进我获得社区和临床理论、研究和设计方面的培训和知识,并补充我在实验酒精研究方面的基础,从而帮助我实现我的研究培训目标和长期职业目标。我为K01提出的职业发展计划包括a)获得社区和临床理论、研究和实践方面的培训;b)加强我在以社区为基础、以临床为重点的酒精干预研究方面的科学出版和研究传播记录;以及c)磨练我的拨款撰写技能,以确保这一新领域的独立资金。我的主要导师玛丽·拉里默博士是临床酒精干预研究领域的知名领导者,我建议的专家合作者和顾问团队完全有资格为我提供所需的监督和支持,以实现我的职业目标并成功完成建议的研究。此外,华盛顿大学的研究和学术环境将在这里实施拟议的职业和研究计划,该环境因其大学环境和在研究和学术培训方面的卓越而得到国际认可。最重要的是,我提出的研究和职业目标与更大的公共卫生问题相关,因为我打算设计、实施、评估和传播针对酒精的干预措施,以改善受严重影响、成本高昂和边缘化人群的酒精、健康和生活质量结果。凭借我在酒精研究方面的深厚背景,以及我对以临床为重点和以社区为基础的干预措施日益增长的兴趣,我相信我是K01奖励机制的有力候选人。在拟议的K01的背景下,我将设计、实施、评估、领导和传播创新的、具有临床意义的、基于社区的酒精干预研究。具体地说,我提议与社区机构市中心紧急服务中心(DESC)合作,并使用CBPR范式来开发和评估一项全面的提高生活酒精管理计划(LEAP),以改善以前患有酒精问题的长期无家可归者的酒精、健康和生活质量。长期无家可归、有酒精问题的人往往同时患有医疗和精神障碍,这可能会转化为公共成本增加,因为更多地使用紧急医疗服务、刑事逮捕和监禁。DESC使用一种创新的方法,以项目为基础的住房优先(HF),为这些严重受影响和边缘化的人口提供支持性住房。在以项目为基础的HF项目中,向个人提供永久的低障碍住房,而不需要戒酒或参加治疗等先决条件。这种方法与降低成本和改善酒精、健康和生活质量结果有关。虽然HF方法与改善目标人群和更大社区的预后有关,但大多数居民继续饮酒,并报告了临床上与酒精相关的重大问题。这一人群在酒精治疗方面也遇到了各种障碍,传统的治疗方案通常无效。传统治疗可能无法吸引这一群体的一个原因是,它只关注禁欲,忽视了个人的整体生活质量和他们饮酒的更大的生物心理社会背景。为了更全面、更有效地满足这一人群的需求,我提出了一个为期5年的项目,以开发和测试在改善酒精、健康和生活质量方面的飞跃的治疗有效性和完整性。这一干预措施将与DESC住房目前采用的低障碍高频方法相兼容,并纳入其中。第一阶段将涉及基线定性数据收集,以确定潜在的加强干预措施点(第1年)。第二阶段将需要以社区为基础的LEAP手册开发(第2年)。第三阶段将包括为期12个月的非随机对照试验(NRCT),测试与基于项目的心力衰竭控制(3年、4年)相比的LEAP有效性。潜在增长模型将被用来测试与IAU相比,在改善酒精使用、健康和生活质量结果方面的LEAP有效性,从基线到3、6和12个月的随访。第四阶段将包括治疗完整性分析,包括手动遵守和能力以及参与者的治疗收据和颁布(第4、5年)。这项研究将为更长期的研究目标奠定基础:LEAP的多点、整群随机对照试验和这一全面的、以证据为基础的计划的更广泛传播。总而言之,我提出的职业发展和研究计划非常符合K01机制以及NIAAA的使命,即进一步提高科学知识,以改善和满足我国与公共卫生相关的研究需求。

项目成果

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Seema Lisa Clifasefi其他文献

Seema Lisa Clifasefi的其他文献

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{{ truncateString('Seema Lisa Clifasefi', 18)}}的其他基金

Social-Ecological Resilience: Adapting a Measure for Individuals with Lived Experience of AUD and Homelessness.
社会生态复原力:针对有澳元和无家可归经历的个人采取措施。
  • 批准号:
    10402620
  • 财政年份:
    2021
  • 资助金额:
    $ 17.44万
  • 项目类别:
A cluster-randomized controlled trial testing the effectiveness of the Life Enhancing Alcohol-management Program (LEAP) for Housing First residents
一项整群随机对照试验,测试住房第一居民的生活改善酒精管理计划 (LEAP) 的有效性
  • 批准号:
    10578691
  • 财政年份:
    2019
  • 资助金额:
    $ 17.44万
  • 项目类别:
A cluster-randomized controlled trial testing the effectiveness of the Life Enhancing Alcohol-management Program (LEAP) for Housing First residents
一项整群随机对照试验,测试住房第一居民的生活改善酒精管理计划 (LEAP) 的有效性
  • 批准号:
    10357932
  • 财政年份:
    2019
  • 资助金额:
    $ 17.44万
  • 项目类别:
A cluster-randomized controlled trial testing the effectiveness of the Life Enhancing Alcohol-management Program (LEAP) for Housing First residents
一项整群随机对照试验,测试住房第一居民的生活改善酒精管理计划 (LEAP) 的有效性
  • 批准号:
    10529057
  • 财政年份:
    2019
  • 资助金额:
    $ 17.44万
  • 项目类别:
A cluster-randomized controlled trial testing the effectiveness of the Life Enhancing Alcohol-management Program (LEAP) for Housing First residents
一项整群随机对照试验,测试住房第一居民的生活改善酒精管理计划 (LEAP) 的有效性
  • 批准号:
    10116236
  • 财政年份:
    2019
  • 资助金额:
    $ 17.44万
  • 项目类别:
Development of LEAP for the Homeless with Alcohol Problems
为有酗酒问题的无家可归者开发 LEAP
  • 批准号:
    8440268
  • 财政年份:
    2013
  • 资助金额:
    $ 17.44万
  • 项目类别:
Development of LEAP for the Homeless with Alcohol Problems
为有酗酒问题的无家可归者开发 LEAP
  • 批准号:
    9000079
  • 财政年份:
    2013
  • 资助金额:
    $ 17.44万
  • 项目类别:
Development of LEAP for the Homeless with Alcohol Problems
为有酗酒问题的无家可归者开发 LEAP
  • 批准号:
    9210029
  • 财政年份:
    2013
  • 资助金额:
    $ 17.44万
  • 项目类别:
The Effects of Alcohol & Placebos on Eyewitness Memory
酒精的影响
  • 批准号:
    7000116
  • 财政年份:
    2005
  • 资助金额:
    $ 17.44万
  • 项目类别:

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儿童健康治疗进展学术培训 (ATTACH)
  • 批准号:
    10409796
  • 财政年份:
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    2008
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