International Society for Extracellular Vesicles - Education Day & Meeting

国际细胞外囊泡学会 - 教育日

• 批准号: 8910966
• 负责人: Kenneth W Witwer
• 金额: $ 1.28万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-04-01 至 2016-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8910966
• 关键词: AIDS/HIV problem; Address; Advertisements; Agreement; Ally; American; American Association of Cancer Research; Antigen Presentation; Apoptotic; Area; Attention; Back; Baltimore; Basic Science; Biological Markers; Biology; Biotechnology; Boston; Caliber; Cell Communication; Cells; Cerebrospinal Fluid; Child; Clinical; Clinical Trials; Coagulation Process; Communicable Diseases; Communication; Communities; Consensus; Development; Device or Instrument Development; Diagnosis; Discipline of Nursing; Disease; District of Columbia; Education; Educational workshop; Employee Strikes; Evaluation; Event; Feedback; Fellowship; Funding; HIV; HIV vaccine; Immune; Immune system; Industry; Influentials; Institution; International; Internet; Investigation; Joints; Journals; Knowledge; Language; Lead; Link; Lipids; Malignant Neoplasms; Maryland; Medical; Medical Research; Medical Students; Methods; Minority; Minority Groups; Mothers; Mutation; Neoplasm Metastasis; Oral; Paper; Paris, France; Pathway interactions; Patient Care; Pharmaceutical Preparations; Pharmacologic Substance; Phase; Philadelphia; Plasma; Positioning Attribute; Procedures; Proteins; Publications; RNA; Rare Diseases; Regulation; Research; Research Personnel; Role; Sampling; Scholarship; Scientist; Services; Site; Societies; Specimen; Speech; Staging; Structure; Teaching Hospitals; Techniques; Technology; Therapeutic; Tissues; Translating; Translations; Travel; Underrepresented Minority; United States National Institutes of Health; Universities; Urine; Validation; Vesicle; Washington; Woman; Work; abstracting; base; biobank; cancer therapy; clinical care; comparative; design; empowered; extracellular; fetal; human disease; insight; meetings; member; novel; oncology; outcome forecast; pathogen; posters; public health relevance; response; single cell analysis; symposium; translational study; tumor; tumorigenesis; web site

 DESCRIPTION (provided by applicant): This R13 application supports the Fourth International Meeting of the International Society for Extracellular Vesicles (ISEV) to be held at the Bethesda North Marriott from April 22-26, 2015. The meeting "Extracellular Vesicles : translating basic science to address human disease" will bring together American clinicians from the Baltimore/Washington medical and biotechnology communities to translate to clinical care the work of the 700 basic scientists of ISEV. Extracellular Vesicles (EV, including "exosomes," "microvesicles," apoptotic bodies, and others) range in diameter from 30 nm to one micron and containing proteins, lipids, RNA, and metabolites derived from the cell of origin. EV act locally i tissues but are also secreted into and can be purified from biofluids. ISEV 2015 will address immune regulation, HIV/AIDS, antigen presentation, coagulation, tissue remodeling, the role of EV in cancer metastasis, diagnosis and prognosis as carriers of tumor-specific protein and RNA mutations, and delivery of therapies. The meeting will begin with an Educational Day, April 22, on isolation of EV from clinical samples, in cooperation with the NIH Common Fund Extracellular RNA Communication Consortium. The Educational Day will feature oral presentations as well as technical workshops led by academic and industry representatives. The main meeting, from April 23-26, will witness a keynote speech by 2013 Nobel Laureate James Rothman. Francis Collins of NIH and EV pioneer Xandra Breakefield of Harvard have also been invited as plenary speakers. Three parallel oral sessions will take place, with a total o 27 thematic sessios, will address pressing issues in EV and medical research. A distinguished international panel, including the editors of ISEV's Journal of Extracellular Vesicles and DC-area researchers, will review submitted abstracts for assign more than 100 oral presentations and 300 thematically-grouped posters. Accessibility and service to underrepresented minorities, women, and young and early stage investigators are priorities. The Educational Day and plenary sessions will be web-broadcast to medical students, researchers in allied fields and underrepresented minority institutions. ISEV plans to provide fifteen traveling fellowships to members of underrepresented minority groups and young investigators. The Conference Center is fully accessible and ADA compliant. A dedicated room will be set up for nursing mothers, and information about daycare options for children or dependent seniors will be offered on the ISEV website and on-site. The ISEV 2015 meeting and the R13 that supports it will host 750-1000 attendees and emphasize consensus standards by which to define and isolate EV and their subtypes; strive for agreements on preparative and isolation techniques and normative specimen biorepositories; and strengthen existing consortia and establish new partnerships for biomarker validation and treatment studies in oncology and infectious diseases, among others. No other meeting offers the scope and participation of ISEV 2015 to address timely questions in the EV field. ISEV 2015 provides an opportunity to combine the international intensity of ISEV's basic and clinical scientists with the vibrant and growing American community of EV investigators in what will surely be the most influential event of 2015 in the EV field.

 描述（由申请人提供）：本R13申请支持将于2015年4月22日至26日在贝塞斯达北万豪酒店举行的国际细胞外囊泡学会（ISEV）第四届国际会议。会议“细胞外囊泡：翻译基础科学，以解决人类疾病”将汇集来自巴尔的摩/华盛顿医疗和生物技术社区的美国临床医生翻译临床护理的700名基础科学家的ISEV的工作。细胞外囊泡（EV，包括“外来体”、“微囊泡”、凋亡小体等）的直径在30 nm至1微米的范围内，并且含有来源于细胞的蛋白质、脂质、RNA和代谢物。EV在组织中局部作用，但也分泌到生物流体中并可从生物流体中纯化。ISEV 2015将解决免疫调节，HIV/AIDS，抗原呈递，凝血，组织重塑，EV在癌症转移中的作用，作为肿瘤特异性蛋白质和RNA突变载体的诊断和预后，以及治疗方法。会议将开始与教育日，4月22日，从临床样本中分离EV，与美国国立卫生研究院共同基金胞外RNA通讯联盟合作。教育日将包括口头报告以及由学术和行业代表领导的技术研讨会。4月23日至26日的主要会议将见证2013年诺贝尔奖得主詹姆斯·罗斯曼的主题演讲。美国国立卫生研究院的弗朗西斯柯林斯和哈佛大学的电动汽车先驱桑德拉·布雷克菲尔德也被邀请作为全体会议的发言人。三个平行的口头会议将举行，共27个专题会议，将解决电动汽车和医学研究中的紧迫问题。一个杰出的国际小组，包括ISEV的细胞外囊泡杂志和DC地区研究人员的编辑，将审查提交的摘要，分配100多个口头报告和300个主题分组海报。优先事项是为代表性不足的少数民族、妇女以及年轻和早期调查人员提供服务。教育日和全体会议将通过网络向医学生、相关领域的研究人员和代表性不足的少数民族机构广播。ISEV计划为代表性不足的少数群体和年轻研究人员提供15个旅行奖学金。会议中心完全无障碍，符合ADA标准。将为哺乳母亲设立一个专门的房间，并在ISEV网站和现场提供有关儿童或受抚养老年人日托选择的信息。ISEV 2015会议和支持它的R13将接待750-1000名与会者，并强调定义和分离EV及其亚型的共识标准;争取就制备和分离技术以及规范的标本生物储存库达成协议;加强现有的联盟，并建立肿瘤学和传染病生物标志物验证和治疗研究的新伙伴关系。没有其他会议提供ISEV 2015的范围和参与度来及时解决电动汽车领域的问题。ISEV 2015提供了一个机会，将ISEV的基础和临床科学家的国际强度与充满活力和不断增长的美国EV研究人员社区相结合，这必将成为2015年EV领域最具影响力的事件。