Research Training Program in Disease-Oriented Neuroscience

描述(由申请人提供)：这项面向疾病的神经科学研究培训计划旨在促进神经学研究生培训和以研究为基础的职业生涯之间的过渡。R25项目实习生将接受经验丰富的神经病学临床科学家和基础研究人员的职业指导，以及宾夕法尼亚大学多个系和学校的临床和实验室研究人员的研究指导。从部门和机构计划中提取的重点教育计划将补充实验室研究，该计划已在前一个项目期间开发和完善，包括翻译研究方法、应用程序和负责任的研究行为方面的培训。该项目是在一家以研究为导向的大型机构进行的，该机构拥有领先的成人和儿童神经病学住院医师项目，培训美国一些最优秀的候选人。在成人和儿童神经病学之间，我们有100多名教职员工，从临床硕士、临床教育工作者、临床研究人员到医生/科学家和基础科学家。在过去的15年里，超过80%的毕业住院医生留在了学术医学领域，许多人选择了临床科学家的职业。佩雷尔曼医学院的宾夕法尼亚大学医院和费城儿童医院是大部分临床实习和奖学金培训的所在地，位于西费城一个高度紧凑的大学校园内，跨度不到半英里。宾夕法尼亚大学也是美国第一个神经科学研究所-马奥尼神经科学研究所，该研究所整合了来自32个系和6所学校的150多名教职员工，从事宾夕法尼亚大学的神经科学研究。因此，我们的R25学员的研究机会范围可以扩展到神经内科内外更广泛的神经科学社区，方法是与从事与NINDS任务相关的研究的学员共同指导，以减轻神经疾病的负担。

DESCRIPTION (provided by applicant): This Research Training Program in Disease Oriented Neuroscience is designed to facilitate the transition between graduate training and a research-based career in neurology. R25 program trainees will receive career mentoring from experienced clinician scientists and basic researchers in Neurology along with research mentoring from clinical and laboratory research faculty in multiple departments and schools within the University of Pennsylvania. A focused educational program drawn from departmental as well as institutional programs will supplement laboratory research has been developed and refined over the prior project period, and includes training in translational research methods, applications, and the responsible conduct of research. The program is conducted in a large research-oriented institution with leading residency programs in adult and child neurology that trains some of the best candidates in the country. Between adult and child neurology, there are over 100 faculty members in our department, ranging from master clinicians, clinical educators, and clinical investigators to physician/scientists and basic scientists. Over 80% of graduating residents over the past 15 years have remained in academic medicine, and many have chosen careers as clinician scientists. The Hospital of the University of Pennsylvania and Children's Hospital of Philadelphia at the Perelman School of Medicine, where most of the clinical residency and fellowship training occurs, are located within a highly compact university campus in West Philadelphia spanning less than one half mile. Penn is also home to the first neuroscience institute in the country, the Mahoney Institute for Neurosciences, which consolidates over 150 faculty members from 32 departments and six schools pursuing neuroscience research at Penn. The range of research opportunities for our R25 trainees can thus be extended to the wider neuroscience community inside and outside the Department of Neurology through co-mentorship of trainees with a diverse array of eminent scientists carrying out research relevant to the NINDS mission to reduce the burden of neurological disease.