Research Program: Cancer Epidemiology, Prevention and Control

研究项目：癌症流行病学、预防与控制

• 批准号: 8804795
• 负责人: POLLY A NEWCOMB
• 金额: $ 7.13万
• 依托单位: FRED HUTCHINSON CANCER RESEARCH CENTER
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-02-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8804795
• 关键词: Appointment; Biological Markers; Biometry; Cancer Center Support Grant; Cancer Survivorship; Child; Clinical; Clinical Trials; Clinical Trials Cooperative Group; Communication; Communities; Contracts; Data; Discipline; Faculty; Funding; General Population; Genetic; Genomics; Goals; Grant; Health Policy; Human; Incidence; Institution; Internal Medicine; Intervention Studies; Laboratories; Leadership; Malignant Neoplasms; Medical Oncology; Medical Surveillance; Mission; Molecular Epidemiology; Morbidity - disease rate; Outcome; Paper; Peer Review; Play; Population; Prevention; Psychology; Publishing; Quality of life; Recruitment Activity; Research; Research Contracts; Research Personnel; Research Project Grants; Resource Sharing; Resources; Risk Reduction; Role; Scientist; Screening for cancer; Sociology; Surveillance Methods; Target Populations; Testing; Training; Translating; Treatment Effectiveness; Underserved Population; Women' s Health; anticancer research; base; cancer epidemiology; cancer therapy; clinical practice; cohort; computer infrastructure; genetic epidemiology; health economics; improved; member; mortality; neoplasm registry; next generation; nutrition; programs; repository; sound

Description and Lay Summary The Cancer Epidemiology, Prevention and Control (CEPC) Program seeks to reduce cancer incidence and mortality through research on environmental and genetic causes of cancer, early detection, risk reduction, and improved outcomes and quality of life. To accomplish this mission, our large, multi-disciplinary faculty conducts clinical and community-based studies in the general population, as well as in targeted and often underserved populations. The CEPC Program currently has 76 members from 14 departments and all three Consortium member institutions, representing multiple scientific disciplines, including epidemiology, genetics, sociology, psychology, internal medicine, medical oncology, communications, nutrition, biostatistics, and health economics. Thirty- nine CEPC faculty have primary appointments at FHCRC, 36 have primary appointments at UW, and one is based at Seattle Children's. CEPC faculty have been successful in obtaining independent funding to support their research: 93% have peer-reviewed cancer related research grants or contracts, are PI on a clinical trial, or are newly recruited investigators, resulting in a research portfolio (direct) totaling $25,984,344 in grants/contract funding, of which $21,616,050 is peer reviewed and $12,793,467 is from NCI. During the previous grant period, CEPC Program faculty published a total of 1655 papers, 25% of which were intra- programmatic, 32% were inter-programmatic, and 17% were inter-institutional. Important program resources include: the Puget Sound Surveillance Epidemiology and End Results (SEER) Cancer Registry, the Molecular Epidemiology and Biomarker Laboratories, large well-maintained cohorts such as the Women's Health Initiative (WHI), clinical trial groups including national coordinating centers, extensive data and biospecimen repositories, the Prevention Center Shared Resource, computational infrastructure and leadership, and nationally-recognized expertise with analysis and interpretation of genomic data. The CEPC Program continues to play an important role in the training of the next generation of cancer research/population scientists.

描述和概述 癌症流行病学、预防和控制（CEPC）计划旨在降低癌症发病率， 通过研究癌症的环境和遗传原因，早期发现，降低风险， 改善结果和生活质量。为了完成这一使命，我们的大型，多学科的教师 在一般人群中进行临床和社区研究，以及在有针对性的， 服务不足的人群。 CEPC计划目前有来自14个部门的76个成员，所有三个联盟成员 机构，代表多个科学学科，包括流行病学，遗传学，社会学，心理学， 内科学、内科肿瘤学、通信学、营养学、生物统计学和卫生经济学。三十- 9名CEPC教师在FHCRC获得主要任命，36名在华盛顿大学获得主要任命，还有1名是 总部设在西雅图儿童医院CEPC教师已成功地获得独立的资金，以支持 他们的研究：93%有同行评审的癌症相关研究赠款或合同，是临床试验的PI， 或者是新招募的研究人员，导致研究组合（直接）总额为25，984，344美元， 赠款/合同供资，其中21，616，050美元经过同行审查，12，793，467美元来自国家癌症研究所。期间 上一个资助期，CEPC计划教师共发表了1655篇论文，其中25%是内部的， 方案性的占32%，方案间的占17%，机构间的占17%。重要方案资源 包括：普吉湾监测流行病学和最终结果（SEER）癌症登记处，分子 流行病学和生物标志物实验室，大型维护良好的队列，如妇女健康 倡议（WHI），临床试验组，包括国家协调中心，广泛的数据和生物标本 存储库、预防中心共享资源、计算基础设施和领导力，以及 国家认可的基因组数据分析和解释专业知识。CEPC计划 继续在培养下一代癌症研究/人口方面发挥重要作用 科学家