Point-of-care ultrasound solutions improving access to diagnostic information for detection of Abdominal Aortic Aneurysms, Trauma (FAST exam) and Pulmonary Edema

 描述（由申请人提供）：超声已被广泛的临床诊断接受，便携式系统已用于紧急护理中的分诊。我们建议通过两项即时诊断开发从根本上改善对检测腹主动脉瘤、创伤（FAST检查）和肺水肿的高质量成像的访问：设备A：手持式相控阵系统，通过USB连接到商用平板电脑，用于显示和供电。设备B：远程医疗相控阵，可由未经培训的用户操作，并生成用于远程判读的体积数据。设备A具有足够低的成本，可以广泛部署给具有基本超声技能的急诊医生和护理人员。设备B是完全独立于操作者的，并且可以由未经训练的个人在农村、航空、救灾和军事环境中使用。远程医生查看器械B采集的体积数据将做出诊断。为了实现这些医疗效益，我们计划将以下方面的创新结合在一起：换能器，以大幅降低系统功耗。我们建议使用最近开发的微机械（MEMS）设备来实现这一点。图像重建。我们的数学方法与标准超声系统中使用的波束形成不同，可以实现紧凑，低成本的电子设备，同时保持高图像质量。系统设计，以实现一个产品的成本，这将大大拓宽进入超声成像在三个目标的应用。在第一阶段，器械A的设计将降低风险并进行规定。第二阶段的目标是生产和临床评估原型。I期和II期开发的技术将直接应用于器械A和器械B的商业化。

 DESCRIPTION (provided by applicant): Ultrasound has found wide clinical diagnostic acceptance, with portable systems already in use for triage in urgent care. We propose to radically improve access to high-quality imaging for detection of Abdominal Aortic Aneurysms, Trauma (FAST exam) and Pulmonary Edema through two point-of-care developments: Device A: a hand-held phased-array system which connects via USB to a commodity tablet for its display and power. Device B: a telemedicine phased-array which can be operated by an untrained user, and generates volume data for remote interpretation. Device A has a low enough cost to be broadly deployed to urgent-care physicians and paramedics with basic ultrasound skills. Device B is entirely operator- independent and can be used by untrained individuals in rural, aviation, disaster-relief and military settings. A remote physician viewing te volume data Device B acquires will make the diagnosis. To deliver these medical benefits we plan to bring together innovations in: Transducers, to substantially decrease system power consumption. We propose using a recently developed micromechanical (MEMS) device to achieve this. Image reconstruction. Our mathematical approach differs from the beam formation in use in standard ultrasound systems and enables compact, low-cost electronics while maintaining high image quality. System design, to achieve a product cost which will significantly broaden access to ultrasound imaging in the three target applications. In Phase I, Device A's design will be risk-reduced and specified. The goal of Phase II is to produce and clinically evaluate a prototype. The technology developed in Phases I and II will be directly applied to commercialization of Device A and Device B.