Hypertension Training Grant

描述（由申请人提供）：高血压这一长期计划的总体目标仍然是培养高度敬业和有才华的年轻研究人员，他们能够在高血压领域以及与这种常见疾病相关的疾病和器官进行高质量的生物医学研究。我们专注于博士后研究人员在学术研究的职业生涯的准备。我们已经增加了新的教师，以扩大到14名科学家和合作资金的新来源超出了UCSD的范围在新的NIH资助中心赠款方面的计划学院。额外的教师构成年轻，但资金充足的教师与特定的人才和成就的转化和临床研究。我们还指定了一组中学初级教师，以增加辅导过程。我们在医学院和系一级得到了UCSD的额外机构支持。UCSD最近还获得了NIH临床和转化科学奖。该计划将提供一系列的兴趣，技能和方法，从基础，转化到临床研究。我们增加了国际公认的外部咨询委员会的监督，并任命了一名内部副项目主任。我们还增加了职业发展课程，以帮助学员掌握学术技能，包括选择最初的教师任命。高血压的最终共同途径是一个复杂的多因素过程，不仅产生终末器官损伤，而且高血压也由器官过程产生，例如，交感神经系统，代谢和内分泌因素，并受到肾脏反应的严重影响。这是一个有竞争力的继续申请，成功地培训了年轻的研究人员，他们在过去的赠款资助周期中以很高的比例被安置在学术职位上。我们决定取消博士前培训计划，专注于博士后培训，这是一个多年来在医学博士和博士学位的学术安置方面享有杰出记录的计划。博士后培训生是从竞争激烈的肾病-高血压奖学金计划的优秀合格申请人中挑选出来的，也是从该计划教师的申请中挑选出来的。我们要求将博士后职位从每年4个增加到5个。代表新学科的教师的招聘加强了该计划。我们强调了招聘的多样性，并强调了正式的课程要求和机会，包括关于正确开展道德研究活动的课程。圣地亚哥是一个丰富的研究环境，并在基础，转化和临床研究提供了广泛的教育机会。因此，该培训计划已经扩大，并在美国各地的学术生涯中获得了重大成功，并继续提供与高血压广泛领域相关的各种研究学科和调查领域。

DESCRIPTION (provided by applicant): The overall goals of this longstanding program in Hypertension remain the training of highly dedicated and talented young investigators capable of performing high quality biomedical research in the area of hypertension and the diseases and organs associated with this common medical condition. We focus upon the preparation of postdoctoral investigators for a career in academic research. We have added new faculty to expand to a Program Faculty of 14 scientists and new sources of cooperative funding extending beyond the confines of UCSD in terms of new NIH funded Center Grants. The additional faculty constitute younger but well funded faculty with specific talents and accomplishments in translational and clinical research. We also designate a group of secondary junior faculty that add to the mentoring process. We have additional institutional support by UCSD at the School of Medicine and Department levels. UCSD has also been awarded a recent NIH Clinical and Translational Science Award. The program will provide a range of interests, skills and approaches, ranging from basic, translational to clinical research. We have added oversight with an internationally recognized External Advisory Committee and appointment of an internal Associate Program Director. We have also added a Career Development course to assist trainees in academic skills including selection of initial faculty appointment. The final common pathway of hypertension is a complex, multifactorial process which not only produces end organ damage, but hypertension is also generated by organ processes, e.g., sympathetic nervous system, metabolic and endocrine factors, and, critically influenced by the response of the kidney. This is a competitive continuation application which has successfully trained young investigators that have been placed in academic positions at a high rate over the past cycle of grant funding. We have decided to eliminate the predoctoral training program and focus upon postdoctoral training, a program that has enjoyed outstanding record of academic placement of M.D.s and Ph.D.s over many years. Postdoctoral trainees are selected from an excellent pool of well qualified applicants from the competitive Nephrology- Hypertension fellowship program and from applications to members of the Program Faculty. We are requesting an increase in postdoctoral positions from 4 to 5 per year. The recruitment of faculty representing new disciplines have strengthened the program. We have emphasized the diversity of recruitments and have emphasized the formal coursework requirements and opportunities including courses on the proper conduct of ethical research activities. San Diego is a rich research environment and provides a wide spectrum of educational opportunities in basic, translational and clinical investigation. Thus, this training program has been expanded and has enjoyed major success in placing trainees in academic careers throughout the USA and continues to provide a wide variety of research disciplines and fields of investigation pertinent to the broad area of hypertension.