Developmental Research Program
发展研究计划
基本信息
- 批准号:9146633
- 负责人:
- 金额:$ 15.15万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2003
- 资助国家:美国
- 起止时间:2003-09-01 至 2021-08-31
- 项目状态:已结题
- 来源:
- 关键词:AddressAwardBasic ScienceBudgetsCancer BiologyCancer PatientClinicalClinical InvestigatorClinical ResearchCollaborationsCommunitiesCommunity DevelopmentsDevelopmentDisciplineDoctor of MedicineDoctor of PhilosophyEarly DiagnosisEducational ActivitiesEndometrialEndometrial CarcinomaFinancial SupportFosteringFundingFutureGenomicsGoalsGynecologicHumanIncidenceInterventionLaboratoriesLeadLettersMalignant NeoplasmsMethodologyMicroRNAsNatureOutcomePathologyPilot ProjectsPlant RootsPreventionPrevention strategyProcessProgram Research Project GrantsQuality of lifeRecruitment ActivityResearchResearch PersonnelResearch Project GrantsResourcesRestScientistSignal TransductionTranslational ResearchUterine CancerWorkanticancer researchbaseeffective therapyflexibilityhigh riskimprovedimproved outcomeinnovationinstrumentationmortalitynovelprofessorprogramssoundsuccesstranslational study
项目摘要
Developmental Research Program SUMMARY/ ABSTRACT
The purpose of the Developmental Research Program (DRP) is to fund promising projects by investigators
whose current work may not focus exclusively on endometrial cancer, but who propose highly innovative
translational studies of endometrial cancer that could become full SPORE projects or compete successfully for
funding outside of the SPORE mechanism. The DRP provides a unique venue for making available significant
financial support, and for demonstrating active institutional support, through a program that is rapidly
responsive to new ideas or initiatives. Moreover, this program is rooted in a spirit of collaboration espoused by
the SPORE investigators, who have an extensive track-record of bringing investigators from other disciplines
into the field of endometrial cancer research. The strength of the Developmental Research Program rests in its
ability to make available financial support and access all the critical expertise and resources within the entire
SPORE, including SPORE Cores. This will allow us to develop important collaborative, multi-investigator, multi-
institutional research projects with the support of innovative, investigator-initiated projects that have the
potential to flourish into reliable and productive translational research projects for the SPORE. Pre-proposals
in the form of 1 page letters of intent will be solicited by the Program, and applicants with pre-proposals that
are highly competitive for the goals of this program will be invited to submit a full proposal for review. The DRP
Directors will help investigators submitting proposals to formulate relevant translational research aims and
plans, as many applicants may not have prior expertise in this type of research. This process will therefore be
a major educational activity that is further anticipated to stimulate translational research in endometrial cancer
and encourage the participation of both basic science researchers and clinical investigators in translational
research. The DRP will be led by Thomas Burke, M.D., the founding Endometrial Cancer SPORE PI and
current Vice President of the MD Anderson Cancer Network, and Wei Zhang, Ph.D., a Professor in the
Department of Pathology with specific expertise in cancer biology, genomics, and construction of miRNA
signaling networks. Russell Broaddus, M.D., Ph.D., SPORE Co-PI, will provide oversight to the DRP. The
DRP is critical to the continued success of the SPORE, as shown by four former DRP awardees now involved
as research project Co-PIs in this application, and a fifth is an important co-investigator on a SPORE project.
Two other former DRP awardees will provide their scientific expertise by serving on the External Advisory
Board.
发展研究计划摘要/摘要
发展研究计划 (DRP) 的目的是资助研究人员有前途的项目
他们目前的工作可能不仅仅专注于子宫内膜癌,但他们提出了高度创新的建议
子宫内膜癌的转化研究可能成为完整的 SPORE 项目或成功竞争
SPORE 机制之外的资金。 DRP 提供了一个独特的场所来提供重要的信息
财政支持,并通过一项迅速实施的计划展示积极的机构支持
对新想法或倡议做出反应。此外,该计划植根于以下组织所倡导的合作精神:
SPORE 调查员,他们在引进其他学科的调查员方面拥有广泛的记录
进入子宫内膜癌研究领域。发展研究计划的优势在于其
有能力提供财务支持并获得整个组织内的所有关键专业知识和资源
SPORE,包括 SPORE 核心。这将使我们能够开展重要的协作、多研究者、多研究
机构研究项目得到了研究者发起的创新项目的支持,这些项目具有
潜力为 SPORE 发展成为可靠且富有成效的转化研究项目。预提案
该计划将征集一页意向书的形式,并提出预提案的申请人
对于该计划的目标具有高度竞争力的人将被邀请提交完整的提案以供审查。发展计划
主任将帮助研究者提交提案,制定相关的转化研究目标和
计划,因为许多申请人可能没有此类研究的先前专业知识。因此,这个过程将是
一项主要的教育活动,预计将进一步促进子宫内膜癌的转化研究
并鼓励基础科学研究人员和临床研究人员参与转化
研究。 DRP 将由子宫内膜癌 SPORE PI 创始人 Thomas Burke 医学博士领导
MD 安德森癌症网络现任副主席,张伟博士,该中心教授
病理学系在癌症生物学、基因组学和 miRNA 构建方面拥有专业知识
信令网络。 Russell Broaddus,医学博士、哲学博士、SPORE 联合首席研究员,将对 DRP 进行监督。这
DRP 对于 SPORE 的持续成功至关重要,四位前 DRP 获奖者现在参与其中表明了这一点
作为该应用程序中的研究项目联合负责人,第五位是 SPORE 项目的重要联合研究员。
另外两名前 DRP 获奖者将通过担任外部顾问来提供他们的科学专业知识
木板。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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THOMAS BURKE其他文献
THOMAS BURKE的其他文献
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{{ truncateString('THOMAS BURKE', 18)}}的其他基金
REGIONAL ACADEMIC ENVIRONMENTAL PUBLIC HEALTH CENTERS
地区学术环境公共卫生中心
- 批准号:
7401639 - 财政年份:2004
- 资助金额:
$ 15.15万 - 项目类别:
REGIONAL ACADEMIC ENVIRONMENTAL PUBLIC HEALTH CENTERS
地区学术环境公共卫生中心
- 批准号:
7401637 - 财政年份:2004
- 资助金额:
$ 15.15万 - 项目类别:
REGIONAL ACADEMIC ENVIRONMENTAL PUBLIC HEALTH CENTERS
地区学术环境公共卫生中心
- 批准号:
7401638 - 财政年份:2004
- 资助金额:
$ 15.15万 - 项目类别:
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