Data Coordinating and Operations Center (DCOC) for the IDeA States Pediatric Clinical Trials Network
IDeA 州儿科临床试验网络数据协调和运营中心 (DCOC)
基本信息
- 批准号:9263498
- 负责人:
- 金额:$ 15.71万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2016
- 资助国家:美国
- 起止时间:2016-09-21 至 2016-09-22
- 项目状态:已结题
- 来源:
- 关键词:Academic Medical CentersAddressAdministratorAgreementAreaArkansasBiomedical ResearchBiometryCenters of Research ExcellenceChildChild health careChildhoodClinicalClinical InvestigatorClinical ResearchClinical TrialsClinical Trials NetworkCongenital AbnormalityCountryCountyDataData CollectionDevelopmentEnrollmentEnsureEnvironmentFacultyFundingHealthHousingHuman ResourcesIndividualInfantInfant MortalityInformaticsInternationalInvestmentsLeadershipLearningLifeLocationLogisticsMedicalMedical EthicsMentorsMolecular EpidemiologyNational Children&aposs StudyNational Institute of Child Health and Human DevelopmentNational Institute of General Medical SciencesOutcomeParticipantPediatric ResearchPopulationPositioning AttributePovertyPreventionProcessProgram DevelopmentPublic HealthRecording of previous eventsRecruitment ActivityResearchResearch InfrastructureResearch PersonnelRuralScienceScientistSiteSystemTechnologyUnited States National Institutes of HealthUniversitiesWorkbiobankbiomedical informaticsclinical careclinical research sitecost effectivedata managementdata sharingdesignexperiencehealth literacyimprovedinnovationmedically underservedmemberoperationprogramsrural areasample collectionsuccessunderserved rural area
项目摘要
PROJECT SUMMARY/ABSTRACT
Each year in Lafayette County, Arkansas, 16 of every 1,000 infants die before their first birthday;1 this infant
mortality rate is greater than that of many second-world countries. Thirty-six percent of Arkansas residents live
in rural areas, almost one in three children lives in poverty, and all counties are medically underserved.2 Arkansas
is an IDeA state and is joined in these disparities by similarly rural states. Infants and children living in rural and
medically underserved IDeA states are less likely than those living in urban states to be enrolled in and benefit
from clinical research, especially clinical trials.3-5 To address this disparity in pediatric research, the
Environmental Influences on Children Health Outcomes (ECHO) initiatives will establish the IDeA States
Pediatric Clinical Trials Network (ISPCTN) to increase representation of and access to clinical trials by children
in underserved states with disproportionately low NIH funding. Up to 15 clinical sites located in IDeA states will
be funded and supported by one Data Coordinating and Operations Center (DCOC). As such, the University of
Arkansas for Medical Sciences (UAMS) proposes to create the DCOC. Being an academic medical center with
a robust clinical research portfolio and experience with conducting research in rural and underserved areas, the
proposed team at UAMS is well positioned to serve as the DCOC. The key personnel work across the four ECHO
priority areas and are prepared to help ISPCTN sites do the same. The DCOC will work collaboratively with
ISPCTN clinical centers to build capability for and increase access to pediatric clinical research in IDeA states
to increase generalizability of trial results. To establish the DCOC, UAMS will:
Specific Aim 1: Establish a coordinating center infrastructure to support trials conducted by the
IDeA States Pediatric Clinical Trials Network. The proposed DCOC will create a cost-effective
operations and data-coordinating infrastructure to support ISPCTN clinical trials.
Specific Aim 2: Execute the operational tasks and scientific responsibilities of the DCOC as
required within the collaborative agreement. The DCOC will support the operations, logistics, data
management, and biostatistics needs of the ISPCTN.
Specific Aim 3: Develop and implement relevant professional development programs to establish
highly competent pediatric clinical trial teams in IDeA states. The DCOC will leverage existing
infrastructure to provide professional development and mentoring.
The objective of the DCOC is to support the development and implementation of clinical research within the
ISPCTN. The UAMS team will work collaboratively with clinical investigators at the ISPCTN sites, Project
Scientists, Program Officials, and other NIGMS and NICHD staff to select or design, implement and oversee
clinical trials addressing the ECHO priority areas and the health needs of children living in IDeA states.
项目总结/文摘
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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{{ truncateString('CHARLOTTE A HOBBS', 18)}}的其他基金
Active Surveillance of Pregnancies Ending in Stillbirths in Arkansas
对阿肯色州以死产告终的妊娠进行主动监测
- 批准号:
9038133 - 财政年份:2015
- 资助金额:
$ 15.71万 - 项目类别:
Birth Defects Study To Evaluate Pregnancy exposureS
评估妊娠暴露的出生缺陷研究
- 批准号:
8911697 - 财政年份:2013
- 资助金额:
$ 15.71万 - 项目类别:
Birth Defects Study To Evaluate Pregnancy exposureS
评估妊娠暴露的出生缺陷研究
- 批准号:
8722863 - 财政年份:2013
- 资助金额:
$ 15.71万 - 项目类别:
Birth Defects Study To Evaluate Pregnancy exposureS
评估妊娠暴露的出生缺陷研究
- 批准号:
8610677 - 财政年份:2013
- 资助金额:
$ 15.71万 - 项目类别:
Genetic and Metabolic Determinants of Congenital Heart Defect Risk
先天性心脏病风险的遗传和代谢决定因素
- 批准号:
7863983 - 财政年份:2009
- 资助金额:
$ 15.71万 - 项目类别:
Centers for Birth Defects Research and Prevention (CBDRPs)
出生缺陷研究和预防中心 (CBDRP)
- 批准号:
7742237 - 财政年份:2008
- 资助金额:
$ 15.71万 - 项目类别:
Centers for Birth Defects Research and Prevention (CBDRPs)
出生缺陷研究和预防中心 (CBDRP)
- 批准号:
8194835 - 财政年份:2008
- 资助金额:
$ 15.71万 - 项目类别:
Centers for Birth Defects Research and Prevention (CBDRPs)
出生缺陷研究和预防中心 (CBDRP)
- 批准号:
8398909 - 财政年份:2008
- 资助金额:
$ 15.71万 - 项目类别:
Centers for Birth Defects Research and Prevention (CBDRPs)
出生缺陷研究和预防中心 (CBDRP)
- 批准号:
7996634 - 财政年份:2008
- 资助金额:
$ 15.71万 - 项目类别:
Centers for Birth Defects Research and Prevention (CBDRPs)
出生缺陷研究和预防中心 (CBDRP)
- 批准号:
7671902 - 财政年份:2008
- 资助金额:
$ 15.71万 - 项目类别:
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