Inductively powering a minimally invasive heart pump

感应式为微创心脏泵供电

• 批准号: 9201810
• 负责人: BOB L PAULY
• 金额: $ 14.95万
• 依托单位: MILLAR, INC.
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-08-15 至 2017-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9201810
• 关键词: Abdomen; Adverse event; Affect; Assisted Circulation; Automobile Driving; Blood flow; Body Temperature; Breathing; Caliber; Caring; Catheters; Clinical Trials; Data; Dependence; Descending aorta; Development; Devices; Diagnosis; Edema; Electricity; Energy Transfer; Fluid overload; Freezing; Goals; Heart; Heart failure; Heating; Hospitals; Implant; Infection; Kidney; Lead; Legal patent; Marketing; Measures; Mechanics; Operative Surgical Procedures; Pacemakers; Patients; Performance; Perfusion; Pharmaceutical Preparations; Population; Pump; Quality of life; Reporting; Research; Risk; Sheep; Skin; Staging; Support System; Surface; Syndrome; System; Technology; Telemetry; Temperature; Testing; Thoracotomy; Translating; Wireless Technology; blood pump; clinical practice; cost; design; experience; improved; magnetic field; minimally invasive; novel; operation; phase 1 study; phase 2 study; phase 3 study; pre-clinical; product development

Heart failure affects over 6 million people in the US alone. Every year, 660,000 new cases are diagnosed with a cost approaching $35 billion. For 2 million of these patients (US), drugs can no longer control the problem and mechanical support for blood flow is the most accessible treatment. However, heart pumps need power, and percutaneous leads used today remain a significant cause of adverse events. We propose eliminating the percutanous lead by using wireless power transfer. Millar (Houston, TX) has develped the technology (US14/432,120) to receive electrical power from a coil inside the body from a magnetic field generated from a coil located outside the body. Our research aim is to show how the merging of the wireless power technology with the Procyrion (Houston, TX) Aortix heart pump can eliminate the risk of percutaneous driveline infections. We will measure the heat generated by the wireless power system when delivering 5W of power over a variable distance of up to 20mm separation between external and implanted coils. This power level is adequate for full pump operation and recharging an internal (short-term) battery. Our long-term goal is make the Aortix the preferred treatment option for stage III HF patients

心力衰竭仅在美国就影响了600多万人。每年有660，000例新病例被诊断为 成本接近350亿美元。对于其中的200万患者（美国），药物已无法控制问题 对血流的机械支持是最容易获得的治疗方法。然而，心脏泵需要动力， 并且目前使用的经皮导线仍然是不良事件的重要原因。我们建议取消 通过使用无线功率传输的经皮电极导线。 Millar（Houston，TX）已经开发了从内部线圈接收电力的技术（US 14/432，120 所述身体不受由位于身体外部的线圈产生的磁场的影响。我们的研究目的是为了证明 无线供电技术与Procyrion（德克萨斯州休斯顿）Aortix心脏泵的合并如何能够 消除经皮传动系统感染的风险。 我们将测量无线电源系统在通过一个 外部线圈和植入线圈之间的距离可变，最多可达20 mm。这个功率水平是足够的 用于全泵运行和内部（短期）电池充电。 我们的长期目标是使Aortix成为III期HF患者的首选治疗选择