Small molecules with large effect: The dual role of nitrogen-containing metabolites in stress tolerance and nutrient recycling

本项目的主要目的是确定耐性小麦对干旱和营养缺乏的反应途径，并为育种计划提供标记，以便于选择优良的育种品系。该项目建立在对水稻进行的一项初步研究的基础上，在该研究中，确定了耐受的特定代谢物，这些代谢物代表了与通过活性氧(ROS)保护细胞免受伤害和胁迫下营养(氮、磷、糖)循环相关的途径。现有数据表明，这些途径在小麦中也是相关的。定量代谢组学、遗传学和分子工具将被用来向育种者提供基于DNA的或代谢组学标记。

The main objective of this project is to identify drought and nutrient-deficiency responsive pathways in tolerant wheat and to provide markers to breeding programs that facilitate selection of superior breeding lines. This project builds on a pilot study conducted in rice in which tolerant-specific metabolites were identified which are representative of pathways relevant for the protection of cells from damage through reactive oxygen species (ROS) and for nutrient (nitrogen, phosphorus, sugars) recycling under stress. Available data suggest that these pathways are also relevant in wheat. Quantitative metabolomics, genetics, and molecular tools will be used to deliver either DNA-based or metabolomics markers to breeders.