2016 Signal Transduction Gordon Research Conference & Gordon Research Seminar

 描述(由申请者提供)：戈登研究会议(GRC)关于工程细胞外基质信号转导的会议成立于2000年，已成为生物工程和干细胞生物学交叉点的首要会议。2010年，戈登-凯南关于工程细胞外基质信号转导的研究研讨会(GRS)启动，现在与GRC一起讨论这一主题。2016年会议将于6月26日至7月1日在ME的新英格兰大学举行，会议强调了重要的新方向：将计算和实验发育生物学和系统生物学与合成基质的设计原则相结合，以及扩大ECM谱以包括粘液。会议主席将由琳达·格里菲斯博士担任，副主席将由萨拉·海尔肖恩博士担任。会议的科学目标将是分享以下方面的最新研究：细胞微环境的发展和调节；工程微环境对个体和集体细胞功能的控制；先进和动态材料的开发；以及将这些见解直接(再生医学)或间接(人类疾病的体外模型)应用于人类临床治疗。因此，这次会议必须聚集生物学(包括干细胞和发育生物学)、化学、系统生物学和工程学等不同领域的研究人员，以了解细胞的功能，以及如何利用细胞功能来修复和替换因疾病或损伤而丢失或损坏的组织，这有助于鼓励跨学科思维。演讲者将包括该领域的知名领导人以及年轻的新兴调查人员，包括那些根据摘要提交的应邀发言的人。在主要会议之前，还将举行一次周末会议，由这一日益增长的跨学科领域的博士后和博士后实习生计划举行。本次会议前的戈登-凯南研究生研究研讨会将为这些未来该领域的领导者提供一个论坛，以演讲和海报的形式展示他们的工作，在一个合作和互动的环境中，这将为他们的整体GRC体验增加突出的价值。总体而言，会议将为发展长期的跨学科互动提供一个平台，并让学生和年轻的专业人员接触到信号转导、分子和细胞生物学、生物材料和组织工程等领域的最新想法和机会。

 DESCRIPTION (provided by applicant): The Gordon Research Conference (GRC) on Signal Transduction by Engineered Extracellular Matrices was established in 2000 and has become the premier meeting at the intersection of bioengineering and stem cell biology. In 2010, the Gordon-Kenan Research Seminar (GRS) on Signal Transduction by Engineered Extracellular Matrices was initiated and now accompanies the GRC on the topic. The 2016 meeting, to be held June 26-July 1 at the University of New England in ME, emphasizes important new directions: integration of computational and experimental developmental and systems biology with design principles for synthetic matrices, and an expansion of the ECM spectrum to include mucus. The meeting Chair will be Dr. Linda Griffith and the Vice-Chair will be Dr. Sarah Heilshorn. The scientific objective of the conference will be to share the newest research on: the development and regulation of cellular microenvironments; the control of individual and collective cell functions by engineered microenvironments; the development of advanced and dynamic materials; and application of such insights to human clinical therapies directly (regenerative medicine) or indirectly (in vitro models of human disease). Thus, this meeting necessarily brings together researchers in diverse fields of biology (including stem cell and developmental biology), chemistry, systems biology and engineering for both the understanding of cellular function and how this can be harnessed for the repair and replacement of tissues lost or damaged due to disease or injury, which serves to encourage cross-disciplinary thinking. Speakers will include well-established leaders in the field as well as young emerging investigators, including those that are invited to present based on abstract submissions. The main conference will also be preceded by a weekend meeting planned by and for pre-doctoral and post-doctoral trainees in this growing interdisciplinary field. This pre-meeting, the Gordon-Kenan Graduate Research Seminar, will provide a forum for these future leaders in the field to present their work in talks and posters, in a collegial and interactive environment that will add outstanding value to their overall GRC experience. Overall, the meeting will provide a platform for the development of long term interdisciplinary interactions, and expose students and young professionals to the latest ideas and opportunities at the confluence of signal transduction, molecular and cellular biology, biomaterials and tissue engineering.