PINPOINT: Gaming technology to engage adolescent sickle cell patients in precision pain management

PINPOINT：游戏技术让青少年镰状细胞病患者参与精准疼痛管理

• 批准号: 9045962
• 负责人: Valerie H Myers
• 金额: $ 22.62万
• 依托单位: KLEIN BUENDEL, INC.
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-01-12 至 2017-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9045962
• 关键词: 17 year old; Abnormal Hemoglobins; Acute; Admission activity; Adolescent; Affect; African American; Age; Arteries; Assessment tool; Blood Vessels; Blood flow; Caring; Cellular Phone; Child; Childhood; Clinical; Cognitive; Collection; Comorbidity; Data; Data Analyses; Development; Elements; Erythrocytes; Focus Groups; Frequencies; Future; Goals; Health; Healthcare; Hematological Disease; Hemoglobin; Hereditary Disease; Hispanics; Hospitals; Hour; Individual; Inherited; Interview; Learning; Left; Life; Measures; Mechanics; Medicine; Methods; Morbidity - disease rate; Multimedia; Names; Organ; Organ failure; Outcome; Pain; Pain Assessment Tool; Pain Measurement; Pain intensity; Pain management; Patient Self-Report; Patients; Personal Satisfaction; Phase; Physicians; Play; Quality of life; Randomized Clinical Trials; Reporter; Research; Research Personnel; Self Care; Series; Severities; Shapes; Sickle Cell; Sickle Cell Anemia; Sickle Hemoglobin; Small Business Innovation Research Grant; Staging; Suggestion; Symptoms; Tablets; Target Populations; Technology; Teenagers; Testing; Thinking; Tissues; Translating; Treatment outcome; Work; acute chest syndrome; adolescent patient; associated symptom; base; clinically significant; cognitive ability; design; digital; effective therapy; experience; health care service utilization; health data; improved; innovation; member; mobile application; mortality; novel strategies; programs; prototype; satisfaction; sickling; social; theories; tool; tool development; treatment choice; usability; user centered design

 DESCRIPTION (provided by applicant): Sickle cell disease (SCD) is the most common inherited blood disorder in the U.S. and disproportionately affects African Americans and Hispanics. Approximately, 1,000 U.S. children are born with SCD annually. SCD results from abnormal hemoglobin and causes red blood cells (RBCs) to become misshaped ("sickle-shaped"). Sickled cells can block the flow of blood in small arteries causing tissue and organ damage and other life- threatening comorbidities. SCD complications can be serious and have a significant impact upon well-being and quality of life. Pain is the hallmark symptom associated with SCD, and is the most common clinical problem seen in children and the number one cause of SCD-related hospital admissions. If left untreated, these painful episodes can result in morbidity and mortality. Accurate assessment of pain specifiers (type, frequency, and intensity of pain) can help with ameliorating pain quickly and effectively. Despite children being accurate self-reporters of their pain, strategies which are effective and engaging to assist with pain identification are lacking. Reducing barriers to collection and promoting the value of accurate SCD pain assessment is a need in pediatric medicine. Pinpoint will be an innovative interactive assessment tool that engages patients while allowing physicians to collect important health data. This project will test the feasibility of applying gamification principles to develop a table application ("app") for 13-17 year olds with SCD. Specifically, this Phase I SBIR project will (1) develop a Pain Assessment Tool (PAT) to describe and categorize specific types of pain experienced by adolescents with SCD; and (2) create an app ("Pinpoint"), that will translate the PAT into gamified technology. The goal of Pinpoint is to engage adolescent patients and improve pain specification by developing a game-based pain assessment tool delivered via a tablet app to engage adolescent SCD patients, improve their pain specification self-report, and improve pain management by clinicians. The PAT will be developed using expert guidance from preeminent SCD clinicians. User-centered Design theory will be applied in the development of the app and will be guided by iterative cognitive interviews and focus groups with members of the target population, SCD teens. The project specific aims are to (1) develop the PAT using guidance from an Expert Advisory Board (EAB) of SCD clinicians; (2) conduct a series of cognitive interviews with adolescent SCD patients to guide and refine PAT development; (3) conduct iterative focus groups with adolescent SCD patients to guide and refine user interface design of the Pinpoint app; (4) program a functional Pinpoint prototype; and (5) conduct usability testing of the prototype with 13-17 year old SCD patients to assess functionality, navigation, and satisfaction. This project is innovative and timely. Pinpoint will be the first tablet app to identfy and translate specific pain types for SCD into a gamified app using applied gamification principles.

 描述（由申请人提供）：镰状细胞病（SCD）是美国最常见的遗传性血液疾病，不成比例地影响非洲裔美国人和西班牙裔。每年大约有1,000名美国儿童出生时患有SCD。SCD由异常血红蛋白引起，并导致红细胞（RBC）变形（“镰刀形”）。镰状细胞可以阻塞小动脉中的血液流动，导致组织和器官损伤以及其他危及生命的合并症。SCD并发症可能是严重的，并对健康和生活质量产生重大影响。疼痛是与SCD相关的标志性症状，是儿童中最常见的临床问题，也是SCD相关住院的头号原因。如果不及时治疗，这些疼痛发作可导致发病率和死亡率。准确评估疼痛说明符（疼痛的类型，频率和强度）可以帮助快速有效地改善疼痛。尽管儿童是准确的自我报告他们的疼痛，有效的和参与，以协助疼痛识别的策略是缺乏的。减少收集障碍和促进准确SCD疼痛评估的价值是儿科医学的需要。Pinpoint将是一个创新的交互式评估工具，可以吸引患者，同时允许医生收集重要的健康数据。该项目将测试应用游戏化原则为13-17岁的SCD儿童开发桌面应用程序（“应用程序”）的可行性。具体而言，该I期SBIR项目将（1）开发疼痛评估工具（PAT），以描述和分类患有SCD的青少年经历的特定类型的疼痛;以及（2）创建一个应用程序（“Pinpoint”），将PAT转化为游戏化技术。Pinpoint的目标是通过开发一种基于游戏的疼痛评估工具来吸引青少年患者并改善疼痛规范，该工具通过平板电脑应用程序提供，以吸引青少年SCD患者，改善他们的疼痛规范自我报告，并改善临床医生的疼痛管理。PAT将在杰出SCD临床医生的专家指导下制定。以用户为中心的设计理论将应用于应用程序的开发，并将通过迭代认知访谈和目标人群（SCD青少年）的焦点小组进行指导。该项目的具体目标是：（1）使用SCD临床医生专家咨询委员会（EAB）的指导开发PAT;（2）对青少年SCD患者进行一系列认知访谈，以指导和完善PAT开发;（3）对青少年SCD患者进行迭代焦点小组，以指导和完善Pinpoint应用程序的用户界面设计;（4）对功能性Pinpoint原型进行编程;和（5）对13-17岁SCD患者进行原型的可用性测试，以评估功能、导航和满意度。该项目具有创新性和及时性。Pinpoint将是第一款使用应用游戏化原则识别SCD的特定疼痛类型并将其转换为游戏化应用程序的平板电脑应用程序。