Mobile Technology and Online Tools to Improve Asthma Control in Adolescents

移动技术和在线工具可改善青少年哮喘控制

• 批准号: 8905986
• 负责人: Jean-Marie Bruzzese
• 金额: $ 63.99万
• 依托单位: 3-C INSTITUTE FOR SOCIAL DEVELOPMENT
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-06-01 至 2017-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8905986
• 关键词: Accident and Emergency department; Address; Adolescent; Affect; Age; Asthma; Caring; Child; Chronic Disease; Clinic; Collaborations; Computer software; Consultations; Diabetes Mellitus; Dose; E-learning; Elements; Evaluation; Exercise; Feedback; Focus Groups; Funding; Goals; Health Insurance; Health Personnel; Healthcare; High School Student; Intervention; Learning; Market Research; Marketing; Medical; Methods; Morbidity - disease rate; National Heart, Lung, and Blood Institute; Online Systems; Outcome; Participant; Persons; Pharmaceutical Preparations; Phase; Pilot Projects; Prevalence; Process; Public Health; Randomized; Randomized Controlled Trials; Recommendation; Relative (related person); Research; Resources; Rest; Risk; Sales; School Nursing; School-Age Population; Schools; Self Management; Services; Small Business Innovation Research Grant; Students; Symptoms; Technology; Testing; Time; Training; Translating; Youth; base; cloud based; commercialization; comparative; design; disability-adjusted life years; eHealth; economic impact; effective intervention; evidence base; experience; health care service utilization; health organization; high school; improved; indexing; intervention effect; mortality; motivational enhancement therapy; novel; pilot trial; post intervention; programs; public health relevance; research and development; response; skills; social cognitive theory; success; tool; twelfth grade; usability

 DESCRIPTION (provided by applicant): Background and Rationale: Asthma is the most common chronic illness affecting youth, with prevalence and morbidity being significant among adolescents. School-based and web-based asthma interventions have been shown to be effective with younger children. Yet, few interventions have been developed and tested with high school students, with only one currently deployed online. The efficacy of Asthma Self-Management for Adolescents (ASMA), an in-person evidence-based high school based intervention, has been established; we have also successfully commercialized technology products for youth that are built on 3C's dynamic e-learning platform (DELP). Objective: This Direct to Phase II SBIR project will fully develop and preliminarily validate ASMA 2.0, an empirically-based dynamic e-health intervention to assist adolescents with uncontrolled asthma to learn how to manage their illness and improve their asthma control. We will apply our demonstrated DELP platform to deploy this demonstrated asthma intervention. Building on ASMA's success, ASMA 2.0 will be grounded in social cognitive theory, motivational interviewing, and best practices for user interface design to create a product that can be disseminated to a broad audience of users. We will accomplish three specific aims: (1) to fully develop ASMA 2.0, including eight modules with core instructional topics, tailored sessions, and embedded interactive activities; (2) to conduct a two group randomized pilot trial with 70, 9th - 12th graders with uncontrolled asthma from two NYC public high schools in order to assess the preliminary intervention effects of ASMA 2.0, and to evaluate the feasibility and acceptability of ASMA 2.0; and (3) to finalize and prepare ASMA 2.0 for commercialization based on feedback from adolescents who participated in the pilot test of ASMA 2.0 and stakeholders who treat and/or educate adolescents with asthma or who are likely payers. We will also evaluate the reach, acceptability, feasibility, and sustainability of the ASMA 2.0 product. Hypotheses: Over two months post-intervention, relative to controls, ASMA 2.0 participants will show significantly greater improvement in asthma-related outcomes. We also hypothesize that ratings and software usage indices will demonstrate that ASMA 2.0 is a feasible, usable, and acceptable intervention for use with adolescents. We will also explore evidence of a dose-response in which participants who spend more time engaged with the e- training materials show greater positive change. Significance: ASMA 2.0 will be the first dynamically adaptive, personalized, interactive software product specifically designed for improving management of asthma and asthma control in adolescents with uncontrolled asthma. As detailed in the Commercialization Plan, ASMA 2.0 will be a unique commercial offering within a large potential market, with revenue being generated through sales to schools, clinics, emergency departments, health insurance companies, and professional health organizations (e.g., local ALA chapters, asthma coalitions).

 描述（由适用提供）：背景和理由：哮喘是影响青年的最常见的慢性疾病，青少年的流行和发病率很高。基于学校和基于Web的哮喘干预措施已被证明对年幼的孩子有效。然而，很少有干预措施与高中生进行了测试，目前仅在网上部署了干预措施。已经建立了哮喘自我管理（ASMA）的哮喘自我管理的效率，这是一种基于循证的高中基于循证的干预措施；我们还成功地为3C的动态电子学习平台（DELP）建立的青年商业化技术产品。目的：这一直接进入第二阶段SBIR项目将充分发展并初步验证ASMA 2.0，这是一种基于经验的动态电子健康干预措施，以帮助青少年不受控制的哮喘，以学习如何管理疾病并改善哮喘的控制。我们将应用我们演示的DELP平台部署这种证明的哮喘干预措施。在ASMA成功的基础上，ASMA 2.0将基于社会认知理论，动机访谈以及用户界面设计的最佳实践，以创建可以传播给广泛用户的产品。我们将完成三个具体目标：（1）充分开发ASMA 2.0，包括八个具有核心教学主题的模块，量身定制的会话和嵌入式互动活动； （2）为了评估ASMA 2.0的初步干预效果，并评估ASMA 2.0的可行性和可接受性； （3）基于参加ASMA 2.0试点测试的青少年的反馈以及对治疗和/或受过教育的青少年患有哮喘或可能是付款人的利益相关者的反馈，以最终确定和准备ASMA 2.0进行商业化。我们还将评估ASMA 2.0产品的覆盖范围，可接受性，可行性和可持续性。假设：在干预后两个月，相对于对照组，ASMA 2.0参与者将在与哮喘相关的结果方面显示出更大的改善。我们还假设评级和软件使用指标将证明ASMA 2.0是可与青少年一起使用的可行，可用且可接受的干预措施。我们还将探讨剂量反应的证据，在这种剂量反应中，花更多时间与电子训练材料互动的参与者显示出更大的积极变化。意义：ASMA 2.0将是第一个动态自适应，个性化的交互式软件产品，专门设计用于改善患有不受控制哮喘的青少年的哮喘和哮喘控制的管理。正如商业化计划中详细介绍的那样，ASMA 2.0将是大型潜在市场中的独特商业产品，通过向学校，诊所，急诊部门，健康保险公司和专业保健组织（例如，当地ALA章节，哮喘联盟）销售收入。