STRENGTHENING NATIONAL CAPACITY IN MALARIA

描述（由申请方提供）：尽管扩大了各种疟疾控制干预措施，但马拉维的疟疾发病率和死亡率仍然高得不可接受。这种高负担可能是由于以下问题造成的：1）方案执行，2）干预措施的吸收和利用，3）缺乏适当的方案监测和评估，以及可能4）缺乏支持方案的相关研究。疟疾预警中心代表马拉维大学医学院申请与美国疾病控制和预防中心签订合作协议，以支持马拉维卫生部努力降低与疟疾有关的发病率和死亡率。该合作协议提案有六个主要目标。目标1包括在马拉维开展疟疾业务研究以及监测和评价活动。卫生部已将收集昆虫学指标确定为该建议中高度重视的关键监测和评估活动之一。目标2将 制定和验证经修订、加强或新的干预措施的影响，这些措施将有助于在马拉维有效控制疟疾。由于马拉维有许多合并症，目标3将评估减少其他传染病负担的战略。目标4包括支持卫生部将许多业务研究结果转化为政策，而目标4和5将改善疟疾监测系统，并建设这些系统的能力， 魔法部为了实现这些目标，已建议进行一些实地和实验室研究。该中心还将建立一个知识中心，促进研究人员和政策制定者之间的沟通，以支持将知识转化为政策。还提出了一些监测和评价活动，包括努力建设能力， 程序.大多数拟议活动都是独特的，与国家和全球疟疾防治议程相关。这些活动将与国家疟疾控制计划合作进行，并得到美国疾病控制和预防中心和其他卓越中心的技术支持。这种合作将建立合理的地方能力，以便今后代表卫生部进行疟疾研究。将与卫生部、总统疟疾倡议、美国国际开发署和其他疟疾执行伙伴分享数据和经验教训，以便更广泛地传播，促进实施循证疟疾干预措施。

DESCRIPTION (provided by the applicant): Morbidity and mortality from malaria remains unacceptably high in Malawi, despite the scale up of various malaria control interventions. This high burden could be as a result of problems in 1) program implementation, 2) uptake and utilization of interventions, 3) absence of a proper program monitoring and evaluation and possibly 4) lack of relevant research to support the program. The Malaria Alert Centre is applying on behalf of the College of Medicine; University of Malawi to undertake a cooperative agreement with the Centers for Disease Control and Prevention, USA to support the Malawi Ministry of Health's efforts to reduce malaria related morbidity and mortality. This cooperative agreement proposal has six main objectives. Objective 1 consists of the conduct of malaria operational research and monitoring and evaluation activities in Malawi. The Ministry of Health has identified collection of entomological indicators as one of the key monitoring and evaluation activities featured highly in this proposal. Objective 2 will develop and validate the impact of revised, enhanced or novel Interventions that will contribute to effective malaria control in Malawi. Since there is a lot of co-morbidities in Malawi, objective 3 will assess strategies to reduce the burden of other infectious diseases. Objective 4 consists of supporting the Ministry of Health in translating the many operational research findings into policy whilst objective 4 and 5 will improve malaria surveillance systems and build capacity for these in the ministry. In order to achieve these, a number of field and laboratory studies have been suggested. The center will also establish a knowledge hub to facilitate communication between researchers and policy makers to support the translation of knowledge into policy. A number of monitoring and evaluation activities have also been proposed, including efforts to build capacity to evaluate the program. Most of the proposed activities are unique and relevant to the national and global malaria control agenda. The activities will be conducted in collaboration with the National Malaria Control Program, with technical support from the Centers for Disease Control and Prevention (USA) and other centers of excellence. This cooperation will build reasonable local capacity to undertake future malaria research on behalf of the Ministry of Health. Data and lessons learnt will be shared with the Ministry of Health, President Malaria Initiative (PMI), USAID and other malaria implementing partners for wider dissemination, to promote the implementation of evidence based malaria interventions.