Malaria Operations Research to Improve Malaria Control and Reduce Morbidity and Mortality in Malawi

RFA-GH-19-015医学院疟疾警报中心 项目总结 马拉维的疟疾发病率和死亡率仍然高得令人无法接受，尽管规模有所扩大。 不同的疟疾控制干预措施。这种高负担可能是由于1)中的问题造成的 方案执行，2)吸收和利用干预措施，3)缺乏适当的 计划监测和评估，以及可能的4)缺乏相关研究来支持 程序。医学院疟疾警报中心正在申请进行一项合作 与美国疾病控制和预防中心达成协议，支持马拉维 卫生部为减少疟疾相关发病率和死亡率所做的努力。这个合作社 协议提案有五个主要目标。目标1包括疟疾的行为 马拉维的业务研究、监测和评价活动。卫生部 除五岁以下儿童和孕妇外，学龄儿童也是弱势群体 女性--这一点在这项提案中得到了高度重视。目标2将制定和验证影响 经修订的、加强的或新颖的干预措施将有助于在#年有效控制疟疾 马拉维。由于马拉维有许多并存的疾病，目标3包括支持 卫生部在将许多业务研究成果转化为政策的同时，客观地 4和5将改进疟疾监测系统，并在卫生部建设这些系统的能力 分别进行了分析。 为了实现这些目标，人们建议进行一些实地和实验室研究。一个 还提出了若干监测和评价活动，包括努力建立 评估计划的能力。大多数拟议的活动都是独一无二的，与 国家和全球疟疾控制议程。这些活动将与以下机构合作进行 在疾病控制中心的技术支持下，国家疟疾控制计划 和预防(美国)和其他卓越中心。这一合作将建立起合理的 代表卫生部开展未来疟疾研究的地方能力。数据和 吸取的经验教训将与卫生部、美国国际开发署疟疾倡议主席分享 和其他疟疾执行伙伴进行更广泛的传播，以促进执行 以证据为基础的疟疾干预措施。

RFA-GH-19-015 College of Medicine Malaria Alert Center PROJECT SUMMARY Morbidity and mortality from malaria remains unacceptably high in Malawi, despite the scale up of various malaria control interventions. This high burden could be as a result of problems in 1) program implementation, 2) uptake and utilization of interventions, 3) absence of a proper program monitoring and evaluation and possibly 4) lack of relevant research to support the program. The College of Medicine Malaria Alert Centre is applying to undertake a cooperative agreement with the Centers for Disease Control and Prevention, USA to support the Malawi Ministry of Health’s efforts to reduce malaria related morbidity and mortality. This cooperative agreement proposal has five main objectives. Objective 1 consists of the conduct of malaria operational research and monitoring and evaluation activities in Malawi. The Ministry of Health has identified school children as a vulnerable group on top of under-five children and pregnant women - this is featured highly in this proposal. Objective 2 will develop and validate the impact of revised, enhanced or novel interventions that will contribute to effective malaria control in Malawi. Since there is a lot of co-morbidities in Malawi, objective 3 consists of supporting the Ministry of Health in translating the many operational research findings into policy whilst objective 4 and 5 will improve malaria surveillance systems and build capacity for these in the ministry respectively. In order to achieve these, a number of field and laboratory studies have been suggested. A number of monitoring and evaluation activities have also been proposed, including efforts to build capacity to evaluate the program. Most of the proposed activities are unique and relevant to the national and global malaria control agenda. The activities will be conducted in collaboration with the National Malaria Control Program, with technical support from the Centers for Disease Control and Prevention (USA) and other centers of excellence. This cooperation will build reasonable local capacity to undertake future malaria research on behalf of the Ministry of Health. Data and lessons learnt will be shared with the Ministry of Health, President Malaria Initiative (PMI), USAID and other malaria implementing partners for wider dissemination, to promote the implementation of evidence based malaria interventions.