Malaria Operations Research to Improve Malaria Control and Reduce Morbidity and Mortality in Malawi

RFA-GH-19-015医学院疟疾预警中心 项目摘要 马拉维的疟疾发病率和死亡率仍然高得令人无法接受， 各种疟疾控制干预措施。这种高负担可能是由于以下问题造成的： 方案实施，2）采取和利用干预措施，3）缺乏适当的 方案监测和评价，以及可能4）缺乏相关研究，以支持 程序.医学院疟疾预警中心正在申请开展一项合作， 与美国疾病控制和预防中心达成协议，支持马拉维 卫生部为降低疟疾相关发病率和死亡率所做的努力。这种合作 协议有五个主要目标。目标1包括开展疟疾防治工作 在马拉维开展业务研究、监测和评价活动。卫生部 已确定学龄儿童是五岁以下儿童和孕妇之外的弱势群体， 妇女-这一点在本提案中占有重要地位。目标2将发展和验证影响 * 修订、加强或新的干预措施，以促进有效控制疟疾， 马拉维.由于马拉维有许多合并症，目标3包括支持 卫生部将许多业务研究结果转化为政策， 4和5将改善疟疾监测系统，并在该部建立这些系统的能力 分别 为了实现这些目标，已建议进行一些实地和实验室研究。一 还提出了一些监测和评价活动，包括努力建立 评估方案的能力。大多数拟议的活动都是独特的，与 国家和全球疟疾防治议程。这些活动将与下列机构合作开展： 在疾病控制中心的技术支持下， 和预防（美国）和其他卓越中心。这种合作将建立合理的 代表卫生部加强当地今后开展疟疾研究的能力。数据和 将与卫生部、总统疟疾倡议（PMI）、美国国际开发署（USAID）分享所吸取的经验教训。 和其他疟疾执行伙伴进行更广泛的传播，以促进执行 基于证据的疟疾干预措施。

RFA-GH-19-015 College of Medicine Malaria Alert Center PROJECT SUMMARY Morbidity and mortality from malaria remains unacceptably high in Malawi, despite the scale up of various malaria control interventions. This high burden could be as a result of problems in 1) program implementation, 2) uptake and utilization of interventions, 3) absence of a proper program monitoring and evaluation and possibly 4) lack of relevant research to support the program. The College of Medicine Malaria Alert Centre is applying to undertake a cooperative agreement with the Centers for Disease Control and Prevention, USA to support the Malawi Ministry of Health’s efforts to reduce malaria related morbidity and mortality. This cooperative agreement proposal has five main objectives. Objective 1 consists of the conduct of malaria operational research and monitoring and evaluation activities in Malawi. The Ministry of Health has identified school children as a vulnerable group on top of under-five children and pregnant women - this is featured highly in this proposal. Objective 2 will develop and validate the impact of revised, enhanced or novel interventions that will contribute to effective malaria control in Malawi. Since there is a lot of co-morbidities in Malawi, objective 3 consists of supporting the Ministry of Health in translating the many operational research findings into policy whilst objective 4 and 5 will improve malaria surveillance systems and build capacity for these in the ministry respectively. In order to achieve these, a number of field and laboratory studies have been suggested. A number of monitoring and evaluation activities have also been proposed, including efforts to build capacity to evaluate the program. Most of the proposed activities are unique and relevant to the national and global malaria control agenda. The activities will be conducted in collaboration with the National Malaria Control Program, with technical support from the Centers for Disease Control and Prevention (USA) and other centers of excellence. This cooperation will build reasonable local capacity to undertake future malaria research on behalf of the Ministry of Health. Data and lessons learnt will be shared with the Ministry of Health, President Malaria Initiative (PMI), USAID and other malaria implementing partners for wider dissemination, to promote the implementation of evidence based malaria interventions.