Clinical Sciences Core (Core C)

临床科学核心(C)项目摘要/摘要 临床科学核心(核心C)由拉斐尔·坎波博士担任主任，查尔斯·米切尔博士和玛格丽特博士领导 Fischl担任联席主任，David Ludwig博士担任生物统计分核心负责人。在过去的4年中，Core C 提供基本服务，既提高了新老调查人员的工作效率，又 促进基础、翻译、行为、社会和临床科学家之间的协作研究。核心C 为70多个项目提供了支持和服务，这些项目得到了NIH各研究所和网络、美国疾病控制与预防中心、 HRSA和制药业，以及试点奖项。在值得注意的核心C成功中，我们有 通过与不同利益相关者的协同互动增加了第二个临床研究单位，我们拥有 确定了将为研究提供新途径的大型数据库。核心C的使命和目标被驱动 由迈阿密CFAR调查人员的研究优先事项，核心尽一切可能支持 这些需求以促进CFAR核心和调查人员之间的协同与合作的方式进行 产生规模经济和努力。核心C提供的支持对我们的调查人员来说是不可或缺的 特别是对我们年轻的调查人员，因为在许多情况下，这种支持不会是 如果不是因为CFAR的存在，它是可用的。具体目标是：目标1.提供最先进的设施 实施临床研究和服务，包括样本和数据收集，并促进培训 /初级调查人员的教育。目标2.提供研究设计方法和技术援助，以满足 涉及人类受试者、人类数据和生物标本的研究的管理标准，以及 3.通过CFAR生物统计分核心提供研究设计和生物统计支持。核心C将服务于 作为一种有价值的资源，提供现有的调查工具和指导支持 通过常规的赠款机制。

Clinical Sciences Core (C) Project Summary/Abstract The Clinical Sciences Core (Core C) is led by Dr. Rafael Campo as Director, Drs. Charles Mitchell and Margaret Fischl as Co- Directors, and Dr. David Ludwig as Biostatistical Subcore leader. During the past 4 years, Core C provided essential services that both enhanced the productivity of new and established investigators and fostered collaborative research among basic, translational, behavioral, social, and clinical scientists. Core C provided support and services for over 70 projects supported by various NIH institutes and networks, the CDC, the HRSA, and the pharmaceutical industry, as well as pilot awards. Among notable Core C successes, we have added a second clinical research unit through synergistic interactions with diverse stakeholders and we have identified large databases that will offer new avenues for research. The mission and goals of Core C are driven by the research priorities of the Miami CFAR investigators, and the Core makes every possible effort to support these needs in a manner that fosters synergy and collaboration between CFAR cores and investigators and produces economies of scale and effort. The support provided by Core C is indispensable to our investigators in general and to our young investigators in particular because, in many instances, this support would not be available were it not for the existence of the CFAR. Specific aims are: Aim 1. Provide state-of-the-art facilities for implementation of, clinical research and services including sample and data collection and to facilitate training /education of junior investigators. Aim 2. Provide research design methodology and technical assistance to meet regulatory standards in research that involves human subjects, human data, and biological specimens, and; Aim 3. Provide research design and biostatistical support through a CFAR Biostatistics Sub-core. Core C will serve as a valuable resource that provides investigative tools and mentoring support beyond that which is available through routine grant mechanisms.