INITIatE: International Collaboration to increase Traumatic Brain Injury Surveillance in Europe

INITIatE：国际合作加强欧洲创伤性脑损伤监测

• 批准号: 9408955
• 负责人: CORINNE PEEK-ASA
• 金额: $ 16.04万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-08-01 至 2019-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9408955
• 关键词: Accident and Emergency department; Admission activity; Affect; Age; Area; Armenia; Brain Injuries; Caring; Case Study; Central Asia; Characteristics; Child; Childhood; Clinical; Clinical Trials; Code; Collaborations; Country; Craniocerebral Trauma; Data; Data Analyses; Data Base Management; Data Collection; Data Quality; Databases; Degree program; Development; Diagnosis; Dictionary; Doctor of Philosophy; Employee Strikes; Ensure; Europe; European; European Union; Evaluation; Family; Follow-Up Studies; Foundations; Funding; Gender; Glasgow Coma Scale; Goals; Grant; Guidelines; Head; Health; Health Policy; Hospitals; Incidence; Income; Individual; Information Systems; Injury; International; Intervention Trial; Iowa; Knowledge; Lead; Life; Location; Longevity; Longitudinal Studies; Maps; Measures; Medical; Middle East; Modeling; Moldova; Monitor; Occupational; Outcome; Patients; Phase; Practice Guidelines; Prevalence; Prevention; Prevention Research; Prevention program; Procedures; Process; Program Development; Protocols documentation; Public Health; Registries; Reporting; Research; Research Activity; Research Infrastructure; Research Methodology; Risk Factors; Romania; Russia; Scanning; Severities; Site; Solid; Standardization; Surveillance Program; System; Training; Training Activity; Training Programs; Translating; Trauma; Traumatic Brain Injury; Traumatic Brain Injury recovery; Treatment Protocols; Treatment outcome; United States; United States National Institutes of Health; Universities; Work; World Health Organization; base; comparative; disability; evidence base; experience; improved; injured; injury burden; injury prevention; innovation; intervention program; low and middle-income countries; low income country; member; pediatric trauma; population based; prevent; prospective; screening; standard care; young adult

The burden of Traumatic Brain Injury (TBI) disproportionately affects low and middle income countries (LMIC), in which TBI prevalence is high and patients are twice as likely to die from their TBI as those in high income countries. LMICs in Eastern European and Central Asia are characterized by growing economies but relatively poor health infrastructures. Consequently, health needs are great, as is potential for improvement. The University of Iowa's Injury Prevention Research Center and Babes-Bolyai University's Center for Health Policy and Public Health located in Cluj-Napoca, Romania are collaborating on this proposed transnational project to increase research capacity in three LMICs, focusing on traumatic brain injury (TBI) data capacity. The project will capitalize on an existing network of research collaborations held by Babes-Bolyai University at three academic centers and hospitals located in Armenia, Georgia, and Moldova: three countries strategically located between Europe, Russia, and the Middle East. The goal of the project is to strengthen institutional research capacity and partnerships among participating countries and to lay a solid foundation on which to build evidence-based prospective research to reduce the incidence and reduce the consequences of TBI. The specific aims are to: 1) identify and describe current TBI data collection practices; 2) develop a comparable TBI registry system; and 3) to conduct comparative analyses of TBI data. The project will be implemented in a number of phases, each of which integrates participatory practices. The first phase will involve an environmental scan and comparative map that identifies current TBI reporting practices and capacity. A comprehensive registry protocol will next be developed by the research team, and implementation of the registry will occur through a monitored process to ensure high data quality. Comparative data analysis to identify the prevalence, patient and injury characteristics, and treatments and procedures will then be conducted. After completing the scope of work outlined in this proposal, we anticipate that our partner countries will have high quality, comparable TBI data and will be ready to initiate clinical and intervention trials. The proposal is innovative in that it will engage US and European experts along with practitioners in LMICs to improve TBI data infrastructure and research capacity using successful models. The project builds on a successful model of collaboration and a team with more than 25 years of experience in research and training activities, including the training of international scholars in research methodology, development of injury registry and surveillance programs, and the development of several international masters and PhD degree programs.

创伤性脑损伤（TBI）的负担不成比例地影响中低收入者 LMIC国家，其中TBI患病率高，患者死于TBI的可能性是LMIC国家的两倍。 与高收入国家的TBI一样。东欧和中亚的中低收入国家是 其特点是经济不断增长，但卫生基础设施相对薄弱。因此，委员会认为， 保健需求很大，改进的潜力也很大。爱荷华州大学的受伤 预防研究中心和婴儿-Bolyai大学卫生政策和公共卫生中心 位于罗马尼亚克卢伊-纳波卡的卫生部正在合作实施这一拟议的跨国项目 提高三个中低收入国家的研究能力，重点关注创伤性脑损伤（TBI）数据 容量该项目将利用现有的研究合作网络，由 Babes-Bolyai大学位于亚美尼亚，格鲁吉亚， 摩尔多瓦：位于欧洲、俄罗斯和中东之间的三个战略性国家 东该项目的目标是加强机构研究能力和伙伴关系 并奠定坚实的基础，在此基础上建立以证据为基础的 前瞻性研究，以减少TBI的发病率和后果。具体 目的是：1）确定和描述当前的TBI数据收集实践; 2）制定一个 可比较的TBI登记系统;以及3）对TBI数据进行比较分析。的 项目将分若干阶段实施，每个阶段都纳入参与性活动， 实践第一阶段将包括环境扫描和比较地图， 确定当前的TBI报告实践和能力。全面的登记研究方案将 下一步将由研究小组制定，登记册的实施将通过一个 监控过程以确保高数据质量。比较数据分析， 患病率，病人和受伤的特点，治疗和程序，然后将 进行。在完成本提案中概述的工作范围后，我们预计， 伙伴国家将拥有高质量、可比的TBI数据，并准备启动临床试验。 和干预试验。该提案的创新之处在于，它将吸引美国和欧洲的专家参与， 沿着与中低收入国家的从业人员一起，利用 成功的模式。该项目建立在一个成功的合作模式和一个团队， 超过25年的研究和培训活动经验，包括培训 国际学者在研究方法，发展伤害登记和监测 课程，并开发了几个国际硕士和博士学位课程。