Developing and testing the feasibility, acceptability and initial efficacy of a brief peer-led intervention to improve reproductive health among women in opioid medication-assisted treatment

开发和测试由同行主导的简短干预措施的可行性、可接受性和初步疗效，以改善阿片类药物辅助治疗中妇女的生殖健康

• 批准号: 9035139
• 负责人: Deborah Rinehart
• 金额: $ 23.06万
• 依托单位: DENVER HEALTH AND HOSPITAL AUTHORITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-06-15 至 2019-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9035139
• 关键词: AIDS prevention; Address; Age; Alcohol or Other Drugs use; Behavior; Behavior Therapy; Behavioral; Child; Child health care; Cognitive; Colorado; Contraception Behavior; Contraceptive Agents; Contraceptive Usage; Contraceptive methods; Coupled; Data; Decision Making; Development; Elements; Family Planning; Female of child bearing age; Focus Groups; Fostering; Goals; Health; Health education; Implant; Individual; Influentials; Intention; Intervention; Intervention Studies; Interview; Intrauterine Devices; Knowledge; Life Experience; Low income; Medicaid; Methods; Modeling; Motivation; Opioid; Participant; Phase; Population; Predisposition; Pregnancy; Pregnant Women; Preventive Intervention; Qualitative Research; Randomized Controlled Trials; Recording of previous events; Reproductive Health; Research; Self Efficacy; Severities; Site; Staging; Structure; Substance Use Disorder; Target Populations; Testing; To specify; Treatment Efficacy; Trust; Visit; Woman; Women' s Health; addiction; base; follow-up; group intervention; health belief; high risk; improved; intervention program; medication-assisted treatment; peer; prevent; reproductive; reproductive health intervention; reversible contraceptive; social; social norm; theories; therapy development; treatment as usual; treatment program; unintended pregnancy; uptake

 DESCRIPTION (provided by applicant): Developing effective reproductive health interventions for women in treatment for substance use disorders has tremendous potential to improve women and children's health. In the US nearly half (51%) of all pregnancies are unplanned (Finer and Zolna, 2014) and a recent study of pregnant women entering opioid medication-assisted treatment found much higher proportions - 86% described their current pregnancy as being unintended (Heil et al., 2011). Women with unintended pregnancies had higher rates of recent substance use and almost all (90%) had a history of prior treatment for substance use disorders. Thus, substance use treatment programs may be promising sites to address contraception and reproductive health. There is a paucity of interventions that specifically focus on preventing unintended pregnancies among women with substance use disorders. This study proposes to use the Health Belief Model (HBM; Rosenstock, 1974) to guide the development of a brief peer-led reproductive health intervention that will be integrated into the substance use treatment setting. Additionally, the intervention will specifically focus on uptake of long acting reversible contraceptive methods as they are considered to be the most effective method of reducing rates of unintended pregnancies (Trussel et al., 2009; Trussell, 2012). Through using mixed methods this study will address the following aims: 1) to use formative methods to better understand contraceptive behaviors and to develop a brief peer-led intervention to prevent unintended pregnancies among women of reproductive age entering opioid medication-assisted treatment; 2) to assess acceptability, feasibility and initial efficacy of the behavioral interventon; and 3) to conduct exploratory analyses to identify the HBM constructs that are most influential on LARC use. Intention-to-treat analyses will be used to assess change in LARC use between baseline and 3 and 6 month follow-up and will test the following hypotheses: participants in the intervention group will be more likely to follow-up with a family planning visit; and participants n the intervention group will be more likely to initiate LARC methods. The long-term goals of this Stage I project are: 1) an intervention that can be tested formally in a larger scale Stage II tria and 2) an enhanced understanding of the HBM constructs involved in contraception decision making and LARC uptake and use.

 描述(由申请人提供)：为治疗药物使用障碍的妇女开发有效的生殖健康干预措施，对改善妇女和儿童的健康具有巨大的潜力。在美国，近一半(51%)的怀孕是计划外怀孕(Finer和Zolna，2014)，最近一项对进入阿片类药物辅助治疗的孕妇的研究发现，这一比例要高得多-86%的人称她们目前的怀孕是意外怀孕(Heil等人，2011年)。意外怀孕的妇女最近的药物使用率较高，几乎所有(90%)都有药物使用障碍的既往治疗史。因此，物质使用治疗方案可能是解决避孕和生殖健康问题的有希望的场所。专门侧重于预防有药物使用障碍的妇女意外怀孕的干预措施很少。这项研究建议使用健康信念模式(HBM；Rosenstock，1974)来指导发展一种简短的同伴主导的生殖健康干预措施，该干预措施将被整合到药物使用治疗环境中。此外，干预将特别侧重于采用长效可逆避孕方法，因为它们被认为是降低意外怀孕率的最有效方法(Trussel等人，2009年；Trussell，2012年)。通过使用混合方法，这项研究将达到以下目标：1)使用形成性方法更好地了解避孕行为，并开发一种简短的同行领导的干预措施，以防止进入阿片类药物辅助治疗的育龄妇女意外怀孕；2)评估行为干预的可接受性、可行性和初步效果；以及3)进行探索性分析，以确定对LARC使用最有影响的HBM结构。意向治疗分析将被用来评估基线和3至6个月随访期间LARC使用的变化，并将检验以下假设：干预组的参与者更有可能后续进行计划生育访问；干预组的参与者更有可能启动LARC方法。这一第一阶段项目的长期目标是：1)可以在更大规模的第二阶段试验中进行正式测试的干预措施；2)加强对涉及避孕决策和LARC吸收和使用的HBM结构的理解。