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中文摘要
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描述(由申请人提供):Evelyn F. and William L. McKnight视力研究中心(MVRC)是迈阿密大学米勒医学院巴斯科姆帕尔默眼科研究所的研究机构。MCVR汇集了来自迈阿密大学和附近机构的48名眼睛和视觉研究人员。42名调查员在巴斯科姆·帕尔默眼科研究所担任初级职务。这项P30核心中心拨款专门针对MVRC研究人员,以整合视觉系统及其疾病的细胞、分子、功能、解剖、生物物理、计算和临床方面的专业知识,并共享核心资源和教育项目。MVRC团队包括21名NEI资助的首席研究员,持有19项合格的NEI资助,以及27名持有非NEI资助的首席研究员。大部分研究空间位于八层的MVRC内。额外的空间位于邻近的生物医学研究大楼、Rosenstiel大楼、Lois Pope LlFE中心、Sylvester综合癌症中心和临床研究大楼。我们请求继续支持视觉研究核心基金,其具体目标是:1)提供和维持核心资源设施,以提高研究的速度和质量,2)促进不同学科研究者之间的合作研究,3)吸引研究者研究视觉系统及其疾病,
英文摘要
DESCRIPTION (provided by applicant): The Evelyn F. and William L. McKnight Vision Research Center (MVRC) is the research arm of the Bascom Palmer Eye Institute, University of Miami Miller School of Medicine. The MCVR draws together 48 eye and vision research investigators across the University of Miami and nearby institutions. Forty-two investigators hold primary appointments in the Bascom Palmer Eye Institute. This P30 core center grant is specifically directed towards MVRC investigators to integrate expertise on cellular, molecular, functional, anatomical, biophysical, computational, and clinical aspects of the visual system and its disorders, as well as share core resources and educational programs. The MVRC Team includes 21 NEI-funded Principal Investigators holding 19 qualifying NEI grants as well as 27 Principal Investigators holding non-NEI funded grants. Most of the research space is located within the eight-story MVRC. Additional space is located in the adjacent Biomedical Research Building, Rosenstiel building, Lois Pope LlFE center, Sylvester Comprehensive Cancer Center, and Clinical Research Building. We request continuing support for a Vision Research Core Grant whose specific aims are, 1) to provide and sustain core resource facilities to enhance the pace and quality of research, 2) to foster collaborative research among investigators from various disciplines, 3) to attract investigators to research on the visual system and its diseases, 4) to help investigators gathering data for new NIH grant proposals. The core grant will support four modules: I) Shared Equipment: to provide access to instrumentation beyond the reach of single labs, II) Experimental Models: to provide expertise and services on in-vivo procedures and testing. III) Biological imaging: to support the processing of biological specimens for quantitative microscopy analysis, IV) Biostatistics: to provide expertise on research design and data analysis. The Bascom Palmer Eye Institute supports additional shared resources including, V) Ophthalmic Biophysics Center: for consultation, maintenance and construction of ad-hoc instrumentation; VI) Clinical Microbiology Laboratory: providing services for clinical and basic research heeds; Vll) The Mary & Edward Norton Library: housing the world's largest collection on the subject of ophthalmology.
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