Miami Center for Vision Research

描述(由申请人提供)：伊夫林·F·麦克奈特和威廉·L·麦克奈特视力研究中心(MVRC)是迈阿密米勒大学医学院巴斯科姆·帕尔默眼科研究所的研究机构。MCVR汇集了迈阿密大学和附近机构的48名眼睛和视觉研究人员。42名研究人员在巴斯科姆·帕尔默眼科研究所担任主要职务。这项P30核心中心赠款专门针对MVRC研究人员，以整合视觉系统及其疾病的细胞、分子、功能、解剖、生物物理、计算和临床方面的专业知识，并共享核心资源和教育计划。MVRC团队包括21名由NEI资助的首席调查员，持有19笔合格的NEI补助金，以及27名持有非NEI资助的补助金的首席调查员。大部分研究空间位于八层楼高的MVRC内。额外的空间位于邻近的生物医学研究大楼、罗森斯蒂尔大楼、洛伊斯·波普生命中心、西尔维斯特综合癌症中心和临床研究大楼。我们请求继续支持视力研究核心补助金，其具体目标是：1)提供和维持核心资源设施，以提高研究的速度和质量；2)促进不同学科研究人员之间的合作研究；3)吸引研究人员研究视觉系统及其疾病， 4)帮助调查人员为新的NIH拨款提案收集数据。核心赠款将支持四个模块：i)共享设备：提供单个实验室无法获得的仪器；ii)实验模型：提供体内程序和测试方面的专业知识和服务。三)生物成像：支持生物标本的处理以进行定量显微镜分析，四)生物统计学：提供研究设计和数据分析方面的专门知识。巴斯科姆·帕尔默眼科研究所支持更多的共享资源，包括：v)眼科生物物理中心：用于咨询、维护和建造特别仪器；vi)临床微生物学实验室：为临床和基础研究提供服务；Vll)玛丽和爱德华·诺顿图书馆：收藏世界上最大的眼科学科藏品。

DESCRIPTION (provided by applicant): The Evelyn F. and William L. McKnight Vision Research Center (MVRC) is the research arm of the Bascom Palmer Eye Institute, University of Miami Miller School of Medicine. The MCVR draws together 48 eye and vision research investigators across the University of Miami and nearby institutions. Forty-two investigators hold primary appointments in the Bascom Palmer Eye Institute. This P30 core center grant is specifically directed towards MVRC investigators to integrate expertise on cellular, molecular, functional, anatomical, biophysical, computational, and clinical aspects of the visual system and its disorders, as well as share core resources and educational programs. The MVRC Team includes 21 NEI-funded Principal Investigators holding 19 qualifying NEI grants as well as 27 Principal Investigators holding non-NEI funded grants. Most of the research space is located within the eight-story MVRC. Additional space is located in the adjacent Biomedical Research Building, Rosenstiel building, Lois Pope LlFE center, Sylvester Comprehensive Cancer Center, and Clinical Research Building. We request continuing support for a Vision Research Core Grant whose specific aims are, 1) to provide and sustain core resource facilities to enhance the pace and quality of research, 2) to foster collaborative research among investigators from various disciplines, 3) to attract investigators to research on the visual system and its diseases, 4) to help investigators gathering data for new NIH grant proposals. The core grant will support four modules: I) Shared Equipment: to provide access to instrumentation beyond the reach of single labs, II) Experimental Models: to provide expertise and services on in-vivo procedures and testing. III) Biological imaging: to support the processing of biological specimens for quantitative microscopy analysis, IV) Biostatistics: to provide expertise on research design and data analysis. The Bascom Palmer Eye Institute supports additional shared resources including, V) Ophthalmic Biophysics Center: for consultation, maintenance and construction of ad-hoc instrumentation; VI) Clinical Microbiology Laboratory: providing services for clinical and basic research heeds; Vll) The Mary & Edward Norton Library: housing the world's largest collection on the subject of ophthalmology.