Training in Emerging Multidisciplinary Approaches to Mental Health and Disease

描述(由申请者提供)：“心理健康和疾病的新兴多学科方法培训(组长)”代表了一个十年之久的培训计划的演变，该培训计划侧重于培训精神病学遗传学领域的博士后研究员。这份续订申请包含了几项实质性的更改和改进。首先，我们正在提议更换领导层。具体地说，亚伯拉罕·帕尔默博士和南希·考克斯博士(多PI)将接替埃利奥特·格尔森博士，后者在过去10年中一直担任项目主任。Gershon博士现年70多岁，继续经营着一家活跃的研究实验室，但将辞去项目主任一职。他将继续留在执行委员会，并将向帕尔默和考克斯博士提供建议，以确保平稳过渡。自培训计划开始以来，南希·考克斯博士一直是该计划的合作伙伴，她将特别参与确定该计划的课程；帕尔默博士也将有大量的智力投入，并将负责“日常”操作。其次，在过去的十年里，这个培训项目只有两个博士后名额，使得它变得异常狭小，使其无法达到临界质量。因此，我们建议大幅扩大该计划，将博士后名额从2个增加到4个。此外，我们还为研究生增加了4个名额，他们将在第二年开始申请资助， 一旦他们加入了我们的一名培训教师的实验室，并选择了一个属于本培训计划范围的项目。第三，培训计划的重点已经扩大并重新聚焦，着眼于满足下一代科学家在未来几十年将面临的需求。例如，对统计和计算方法的重视程度要高得多，这与最近资助的Conte计算系统神经精神病学表型基因组学中心和正在发展中的格罗斯曼研究所的密切整合是相辅相成的。为了实现该计划的新目标，已经招募了更多的培训人员，特别是来自人类遗传学系的培训人员。由于这些变化，培训教师的总体规模几乎翻了一番。学生将获得为期两年的资助。名额的数量是基于博士后和博士后水平的极高质量的申请者。博士生预科生将 来自不同的相关部门和研究生项目。芝加哥大学提供了一个独特的环境，具有悠久的跨学科合作历史，这将使学员受益。学员之间的科学互动将是广泛的，并将是 通过纳入更大的博士后和博士后队列来加强这一点。正式的机制将包括学生正在进行的工作和日记俱乐部的陈述，实习生邀请的演讲者，以及教学课程，这些课程将被重新安排为全天的静修活动，并将包括一次社交午餐。将在招募任职人数不足的少数群体和开展研究道德培训方面作出更大和适当的努力。

DESCRIPTION (provided by applicant): The "Training in Emerging Multidisciplinary Approaches to Mental Health and Disease (TEAM HEAD)" represents the evolution of a ten year old training program that has focused on training postdoctoral fellows in the area of psychiatric genetics. This renewal application contains several substantial changes and improvements. First, we are proposing a change of leadership. Specifically, Drs. Abraham Palmer and Nancy Cox (multiple-PIs) will replace Dr. Elliot Gershon, who has served as Program Director for the last 10 years. Dr. Gershon, who is now in his 70s, continues to run an active research lab, but is stepping down as Program Director. He will remain on the executive committee and will provide advice to Drs. Palmer and Cox to assure a smooth transition. Dr. Nancy Cox has been a co-I since the training program's inception and will be particularly involved in determining the program's curriculum; Dr. Palmer will also have significant intellectual input and will be responsible for "day-to-day" operations. Second, for the past ten years this training program has only had two postdoctoral slots, making it unusually small and preventing it from obtaining a critical mass. Thus, we are proposing to substantially expand the program by increasing the number of postdoctoral slots from 2 to 4. Furthermore, we are adding four slots for graduate students, who will apply for support at the beginning of their second year, once they have joined the lab of one of our training faculty and selected a project that is within the scope of this training program. Third, the focus of the training program has been broadened and refocused with an eye towards meeting the demands that the next generation of scientist will face in the coming decades. For example, there is a much greater emphasis on statistical and computational approaches, which is complimented by close integration with a recently funded Conte Center for Computational Systems Genomics of Neuropsychiatric Phenotypes and the developing Grossman Institute. Additional training faculty, particularly from the Department of Human Genetics, have been recruited to meet the new goals of the program. The overall size of the training faculty has almost doubled as a result of these changes. Students will be supported for 2 years. The number of slots is based on the extremely high quality pool of applicants at both the pre- and post-doctoral levels. Pre-doctoral students will be drawn from a variety of relevant departments and graduate programs. The University of Chicago provides a unique environment with a long history of interdisciplinary collaboration that will benefit the trainees. The scientific interactions among the trainees will be extensive, and will be enhanced by inclusion of a larger cohort of both pre- and post-doctoral students. Formal mechanisms will include student work-in-progress and journal club presentations, trainee- invited speakers, and didactic classes that will be re-structured as full-day retreats and will include a social luncheon. Expanded and appropriate efforts will be made with regard to recruitment of underrepresented minorities and training in ethical conduct of research.