2018 Plasminogen Activation and Extracellular Proteolysis Gordon Research Conference and Gordon Research Seminar

摘要 为2018年纤溶酶原激活和胞外蛋白分解戈登寻求资金支持 研究会议(GRC)和戈登研究生研究研讨会(GRS)。这些是配对的会议 在同一地点连续举行，GRS为2月10日至11日，GRC为2018年2月11日至16日。 自1990年以来，GRC每两年连续举办一次，在国际上享有杰出的 声誉。我们将讨论在纤溶酶原激活和细胞外蛋白分解方面的突破性发现 血管生物学、中枢神经系统功能和功能障碍、创伤、痴呆、妊娠、组织 动态平衡与再生，造血，干细胞生物学，新陈代谢与肥胖，肿瘤生物学， 心血管功能和血管生成。对于2018年会议，重点将放在翻译 科学将是构成本次会议概念框架的三个“T”的一部分： 翻译性、过渡性和技术性。为了实现我们的翻译目标，我们将做出重大努力 邀请内科医生和科学家讨论需要基础科学产生的特定知识的临床需求 让研究人员感到满足。过渡目标将使我们能够在我们的实地进行非常必要的过渡。 从资深研究人员到年轻研究人员。因此，将作出重大努力，让年轻的调查人员 重点是妇女、少数群体和那些没有机会介绍他们的科学发现的人 在过去的GRC会议上。为了达到技术目标，新的技术进步和切割- 将讨论蛋白水解酶领域中新疗法的前沿。与会者将通过邀请和 来自在线提交的申请。他们将被选为代表不同领域的研究人员，以及 特别强调将妇女和代表性不足的少数群体纳入讨论。 领导人和演讲者，以及海报主持人和与会者。关联的GRS是一种新功能 这将为年轻科学家提供一个分享GRC经验的独特机会。这两天 研讨会将由研究生和博士后研究员在Leading支持下组织 研究人员和GRC主席，并将允许纤溶酶原激活和 胞外蛋白分解走到一起讨论他们目前的研究，同时建立非正式网络 与他们的同龄人合作，可能会导致终身合作和科学成就。

Abstract Funds are sought for partial support for the 2018 Plasminogen Activation and Extracellular Proteolysis Gordon Research Conference (GRC) and Gordon Graduate Research Seminar (GRS). These are paired conferences held sequentially at the same location, on February 10-11 for the GRS, and February 11-16, 2018 for the GRC. The GRC has been held continuously every two years since 1990 and enjoys an outstanding international reputation. We will discuss breakthrough findings in plasminogen activation and extracellular proteolysis in vascular biology, central nervous system function and dysfunction, trauma, dementia, pregnancy, tissue homeostasis and regeneration, hematopoiesis, stem cell biology, metabolism and obesity, tumor biology, cardiovascular function, and angiogenesis. For the 2018 meeting, emphasis will be placed on Translational Science which will be part of the three "T's" that will constitute the conceptual framework for this conference: translational, transitional and technological. To accomplish our translational goal a major effort will be made to bring Physician-Scientists to discuss clinical needs that need specific knowledge generated by basic science researchers to be fulfilled. The transitional goal will allow us to make a very much-needed transition in our field from senior researchers to younger investigators. Thus, a major effort will be made to bring young investigators with emphasis on women, minorities and those who have no had the chance to present their scientific findings in past GRC meetings. To attain the technological objective novel technological advances and the cutting- edge in new therapies in the field of proteases will be discussed. Attendees will be selected by invitation and from applications submitted online. They will be chosen to represent a diverse spectrum of researchers, and a strong emphasis has been made on the inclusion of women and underrepresented minorities as Discussion Leaders and Speakers, as well as on Poster Presenters and Attendees. The associated GRS is a novel feature that will provide a unique opportunity for young scientists to share in the GRC experience. This two-day seminar will be organized by Graduate Students and Postdoctoral Fellows with the support of leading researchers and the GRC Chair, and will allow junior researchers within the field of plasminogen activation and extracellular proteolysis to come together to discuss their current research, while building informal networks with their peers that may lead to a lifetime of collaboration and scientific achievement.