Neurobehavior, Neuropathology, and Risk Factors in Alzheimer's Disease

阿尔茨海默病的神经行为、神经病理学和危险因素

• 批准号: 9265401
• 负责人: ELAINE R. PESKIND
• 金额: $ 33.25万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-05-01 至 2021-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9265401
• 关键词: Alzheimer' s Disease; Risk Factors; neurobehavior; neuropathology

 DESCRIPTION (provided by applicant): We are applying for funding of our Alzheimer's disease Training Program (ADTP), "Neurobehavior, Neuropathology, and Risk Factors in Alzheimer's Disease." Our program focuses on translational research in Alzheimer's disease (AD) and related dementias. The objective of our research training program is to provide interdisciplinary training for basic science, clinical, and translational researchers so that they ill be able to advance clinical hypotheses about the etiology, pathophysiology, and treatment of AD and related disorders. Our training program is the only formal program at the University of Washington focused on training investigators to carry out basic, clinical, and translational research in AD and related neurodegenerative dementing disorders. Our program is supported by the rich and interactive research environment of the University of Washington and Veterans Affairs Puget Sound Health Care System, where a critical mass of faculty conduct research across the spectrum of AD and related dementias. The program is requesting training positions for 5 postdoctoral trainees. For postdoctoral trainees our goal is to have ~40% clinical (MD, MD/PhD, or PhD in Clinical Psychology) and ~60% research (PhD) postdoctoral fellows. Incoming MD candidates are expected to have completed a residency, usually in psychiatry, neurology, neuropathology, radiology, internal medicine, or geriatric medicine. Postdoctoral PhD candidates from come a broad range of disciplines, including clinical psychology, neuropsychology, biochemistry, genetics, neurobiology, and pharmacology. Basic science trainees typically join the program during their 1st year of postgraduate training and usually remain for three years. MD and clinician PhD fellows are expected to remain for a two year period, and will be strongly encouraged to remain for a third. We are also requesting training positions for 4 predoctoral candidates. Predoctoral trainees will be recruited from the following UW PhD programs: Genome Sciences, Molecular Basis of Disease, Molecular and Cellular Biology, Neurobiology and Behavior, and Pharmacology, and will join the ADTP program in their 2nd or 3rd year of graduate training. Special recruitment efforts will be made to include underserved minority trainees.

 描述(由申请者提供)：我们正在申请资助我们的阿尔茨海默氏病培训计划(ADTP)，“阿尔茨海默氏病的神经行为，神经病理，和风险因素”。我们的项目专注于阿尔茨海默病(AD)和相关痴呆的翻译研究。我们的研究培训计划的目标是为基础科学、临床和翻译研究人员提供跨学科培训，使他们能够提出关于AD和相关疾病的病因、病理生理学和治疗的临床假说。我们的培训项目是华盛顿大学唯一的正式项目，专注于培训研究人员在AD和相关的神经退行性痴呆障碍方面进行基础、临床和翻译研究。我们的计划得到了华盛顿大学和退伍军人事务部Puget Sound Health Care System丰富和互动的研究环境的支持，在那里，关键的教职员工开展各种AD和相关痴呆症的研究。该计划正在招聘5名博士后实习生的培训职位。对于博士后实习生，我们的目标是拥有~40%的临床(医学博士、医学博士/博士或临床心理学博士)和~60%的博士后研究员。新来的医学博士候选人需要完成住院医师资格，通常是精神病学、神经学、神经病理学、放射学、内科或老年医学。博士后候选人来自广泛的学科，包括临床心理学、神经心理学、生物化学、遗传学、神经生物学和药理学。基础科学实习生通常在研究生培训的第一年参加该项目，通常会停留三年。医学博士和临床博士研究员预计将留任两年，并将强烈鼓励留任第三年。我们还要求提供4名博士前候选人的培训职位。博士前实习生将从以下UW博士项目中招募：基因组科学、疾病分子基础、分子和细胞生物学、神经生物学和行为以及药理学，并将在研究生培训的第二年或第三年加入ADTP计划。将作出特别招聘努力，以吸纳服务不足的少数族裔受训人员。