The Cooperative Re-Engagement Controlled Trial (CoRECT

描述（由申请人提供）：马萨诸塞州公共卫生部（MDPH）传染病局（BID）将通过使用监测数据来评估一种新的公共卫生干预措施的有效性，以（重新）参与确定为护理外的PLWHA。拟议的研究项目“马萨诸塞州对健康护理的保留、参与和坚持”（MassREACH）可以显著提高对ART的护理参与和坚持，从而有助于降低发病率，改善个人和人口水平的健康结果，并减少健康差距。具体目标目标1：建立数据共享伙伴关系，以确定护理外的目标目标2：实施参与护理干预目标3：计算参与和保留护理的护理外的艾滋病病毒卫生工作者的数量和百分比，并实现病毒抑制目标4：描述卫生部门-诊所合作的重要组成部分和可行性，以确定护理外的艾滋病病毒卫生工作者从改善再参与个体的健康状况和减少向前传播方面衡量干预组的成本效益。目的6：描述解释护理状况错误分类的原因。目的7：在研究开始和结束时测量病毒抑制情况，以估计该干预在社区一级的潜在影响。MDPH建议将MassREACH作为一项战略，以评估一种新的公共卫生干预措施的有效性，以（重新）参与被确定为脱离护理的艾滋病患者。该项目将以预防和控制艾滋病毒和性传播疾病的现有公共卫生基础设施为基础，并将通过使用新的战略和技术补充现有的联系和参与活动。

DESCRIPTION (provided by applicant): The Massachusetts Department of Public Health (MDPH) Bureau of Infectious Disease (BID) will evaluate the effectiveness of a novel public health delivered intervention, driven by use of surveillance data, to (re-)engage PLWHA identified as out-of-care. The proposed research project, the "Massachusetts Retention, Engagement, and Adherence to Care for Health" (MassREACH), could significantly improve care engagement and adherence to ART, thereby contributing to reduced incidence, individual and population level improvements in health outcomes, and reductions in health disparities. Specific Aims Aim 1: Establish data sharing partnerships to identify out-of-care Aim 2: Implement an engagement in care intervention Aim 3: Calculate the number and percentage of out-of-care PLWH engaged and retained in care, and who achieve viral suppression Aim 4: Describe the important components and feasibility of a health department-clinic collaboration to identify out- of-care PLWHA Aim 5: Measure the cost-effectiveness of the intervention arm in terms of improved health of re-engaged individuals and reduced forward transmission Aim 6: Describe reasons that explain care status misclassifications Aim 7: Measure viral suppression at the beginning and end of the study to estimate the potential impact of this intervention at the community level. The MDPH proposes MassREACH as a strategy to evaluate the effectiveness of a novel public health delivered intervention to (re-)engage PLWHA identified as out-of-care. The project will build upon the existing public health infrastructure for HIV and STD prevention and control, and will complement existing linkage and engagement activities through use of novel strategies and techniques.