The Cooperative Re-Engagement Controlled Trial (CoRECT

合作再参与对照试验 (CoRECT

• 批准号: 9327689
• 负责人: ALFRED DEMARIA
• 金额: $ 64.55万
• 依托单位: MASSACHUSETTS STATE DEPT OF PUB HEALTH
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-01 至 2019-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9327689
• 关键词: Cooperative; Re; Engagement; Controlled; Trial

DESCRIPTION (provided by applicant): The Massachusetts Department of Public Health (MDPH) Bureau of Infectious Disease (BID) will evaluate the effectiveness of a novel public health delivered intervention, driven by use of surveillance data, to (re-)engage PLWHA identified as out-of-care. The proposed research project, the "Massachusetts Retention, Engagement, and Adherence to Care for Health" (MassREACH), could significantly improve care engagement and adherence to ART, thereby contributing to reduced incidence, individual and population level improvements in health outcomes, and reductions in health disparities. Specific Aims Aim 1: Establish data sharing partnerships to identify out-of-care Aim 2: Implement an engagement in care intervention Aim 3: Calculate the number and percentage of out-of-care PLWH engaged and retained in care, and who achieve viral suppression Aim 4: Describe the important components and feasibility of a health department-clinic collaboration to identify out- of-care PLWHA Aim 5: Measure the cost-effectiveness of the intervention arm in terms of improved health of re-engaged individuals and reduced forward transmission Aim 6: Describe reasons that explain care status misclassifications Aim 7: Measure viral suppression at the beginning and end of the study to estimate the potential impact of this intervention at the community level. The MDPH proposes MassREACH as a strategy to evaluate the effectiveness of a novel public health delivered intervention to (re-)engage PLWHA identified as out-of-care. The project will build upon the existing public health infrastructure for HIV and STD prevention and control, and will complement existing linkage and engagement activities through use of novel strategies and techniques.

描述（由申请人提供）：马萨诸塞州公共卫生部（MDPH）传染病局（BID）将评估一种新的公共卫生干预措施的有效性，该干预措施由监测数据驱动，以（重新）接触被确定为脱离护理的PLWHA。拟议的研究项目，“马萨诸塞州保留，参与和坚持保健”（MassREACH），可以显着提高护理参与和坚持抗逆转录病毒疗法，从而有助于降低发病率，个人和人口水平的改善健康结果，并减少健康差距。具体目标目标1：建立数据共享伙伴关系，以识别护理外目标2：实施护理干预的参与目标3：计算护理外艾滋病毒携带者和艾滋病病毒携带者的数量和百分比，以及获得病毒抑制的人数和百分比目标4：描述卫生部门-诊所合作的重要组成部分和可行性，以识别护理外艾滋病毒携带者和艾滋病病毒携带者目标5：衡量干预组在改善重新参与个体的健康和减少前向传播方面的成本效益目标6：描述解释护理状态错误分类的原因目标7：在研究开始和结束时测量病毒抑制，以估计这种干预在社区水平上的潜在影响。MDPH建议将MassREACH作为一项战略，以评估一种新的公共卫生干预措施的有效性，以（重新）参与被确定为脱离护理的艾滋病毒/艾滋病感染者。该项目将利用现有的艾滋病毒和性传播疾病预防和控制公共卫生基础设施，并将通过使用新的战略和技术补充现有的联系和参与活动。