Multidisciplinary Training Program in Basic Diabetes Research

描述（由申请人提供）：糖尿病及其并发症的负担强调了学术研究机构和糖尿病研究人员需要培养合格的研究科学家，以开发治疗，预防和治愈糖尿病的新途径。该培训基金的主要目标是通过多学科和全面的学习经验，科学互动和指导，培养博士基础科学家从事糖尿病研究，以加深对糖尿病分子方面的理解。该培训项目嵌入了密歇根大学丰富的研究环境中，其中包括一个高度合议的跨学科糖尿病研究社区和优秀的生物医学研究核心资源。培训计划建立在糖尿病发病机制及其并发症不同组成部分的独特专业知识的基础上。培训补助金的受训者可分为六个主要兴趣组——胰岛生物学、自身免疫性糖尿病、脂肪细胞生物学、下丘脑代谢调节、胰岛素抵抗和代谢控制机制（肝脏、脂肪细胞和肌肉群）以及糖尿病并发症。该计划包括在个别实验室的培训，但辅以糖尿病分子发病机制的核心课程，以及一系列跨学科和合作的教育项目会议、研讨会、活动

DESCRIPTION (provided by applicant): The burden of diabetes and its complications stresses the need for academic research institutions and diabetes researchers to train well-qualified research scientists to develop new avenues for the treatment, prevention and cure of diabetes. The primary goal of this training grant is to train PhD basic scientists for careers in diabetes research using a multidisciplinary and comprehensive learning experience, scientific interactions and mentorship to develop a deep understanding of the molecular aspects of diabetes. This training program is embedded within the rich research environment of the University of Michigan, which includes a highly collegial, and interdisciplinary diabetes research community and excellent core resources for biomedical research. The training program builds on the unique expertise of the group of preceptors in different components of the pathogenesis diabetes and its complications. Training grant preceptors fall into six major interest groups - islt biology, autoimmune diabetes, adipocyte biology, hypothalamic regulation of metabolism, mechanisms of Insulin resistance and metabolic control (liver, adipocyte and muscle groups) and diabetes complications. The program includes training in the individual laboratory but is supplemented by a core curriculum in molecular pathogenesis of diabetes as well as an interdisciplinary and collaborative series of educational project meetings, seminars, activities in grant writing, career advance and research methodologies. This training will provide the necessary tools for transition to independence. This program includes 18 mentors in a highly collaborative environment with stable extramural funding who have appointments in nine separate departments in the School of Medicine and two Divisions within the Department of Internal Medicine. This program will provide a significant complement for the training mission of the Michigan Diabetes Research Center and the Nutrition and Obesity Research Center. The training program will be administered through the Division of Metabolism Endocrinology and Diabetes, and will be overseen by an executive committee comprising the Principal Investigator, one co-director and four members of whom are senior investigators with strong mentoring track records.