The Association Between Diet and Bowel Preparation

饮食与肠道准备之间的关系

基本信息

批准号：
9116186
负责人：
BRIAN C JACOBSON
金额：
$ 17.58万
依托单位：
BOSTON MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-07-29 至 2018-06-30
项目状态：
已结题

项目摘要

DESCRIPTION (provided by applicant): An estimated 11 to 14 million colonoscopies are performed annually in the United States, yet very limited information exists describing the impact of specific foods consumed on the days prior to the pre-colonoscopy bowel preparation. Consequently, any recommended dietary restrictions that accompany bowel purgatives are based on limited scientific evidence and vary across endoscopy units. These non-standardized dietary restrictions place constraints on people preparing for a colonoscopy and may result in decreased patient satisfaction with the procedure and perhaps decreased compliance with the preparation. If specific dietary restrictions are indeed necessary to ensure maximizing the endoscopist's ability to detect malignant or pre- malignant lesions, then identification of optimal instructions becomes an important public health endeavor. The proposed nutritional study will begin to examine, in a novel and rigorous manner, the effect of diet on adequacy of bowel preparation for colonoscopy. This study will address observed national variability in pre- colonoscopy dietary instructions and permit, for the first time, the development of evidence-based, culturally- sensitive dietary options for patients preparing for colonoscopy. A secondary aim is the validation of a novel, bowel preparation classification scale that describes colonic contents during colonoscopy. This proposed new scale was designed specifically to measure the impact of dietary interventions in the days preceding colonoscopy for nutritional research.

描述（由适用提供）：每年在美国每年进行11至1400万个结肠镜检查，但存在非常有限的信息，这些信息描述了在骨镜检查前肠子准备前几天消耗的特定食物的影响。因此，任何参与肠炼狱的建议饮食限制都是基于有限的科学证据，并且在内窥镜单位之间有所不同。这些非标准化的饮食限制对为结肠镜检查做准备的人限制了限制，并可能导致患者对手术的满意度降低，并可能降低了对制剂的依从性。如果确实需要具体的饮食限制，以确保内窥镜检测恶性肿瘤或恶性病变的能力，则可以识别最佳说明成为重要的公共卫生努力。拟议的营养研究将开始以新颖而严格的方式开始检查饮食对结肠镜检查是否足够的饮食的影响。这项研究将解决观察到的国家术前饮食饮食指示中的国家变异性，并首次允许开发基于证据的，具有文化敏感的饮食选择，以准备进行结肠镜检查。次要目的是对描述结肠镜检查中结肠含量的新颖的肠制备分类量表的验证。该提出的新规模专门旨在衡量结肠镜检查对营养研究的日子的饮食干预措施的影响。