The University of Washington Patient Centered Outcomes Research Partnership (PCOR

描述（由申请人提供）：美国的医疗保健系统面临着关于哪些医疗保健决策真正改善人口健康的复杂问题。为了回答这些问题，我们需要新的研究人员，他们可以对以患者为中心的结果和药物治疗的比较有效性进行创新，务实的研究。这些研究人员必须能够在各种复杂的医疗环境中实施比较有效性研究（CER）和以患者为中心的结局研究（PCOR）的结果。我们建议制定一个由知识产权持有人驱动的教育和体验式培训计划，为科学家和临床医生开展CER和PCOR做好准备。我们的计划包括关注美国印第安人和阿拉斯加原住民的社区医疗保健，这是一个服务不足的人口。学员将受益于体验式培训，这些培训由华盛顿大学的CER/PCOR专家指导，并由我们的四个合作伙伴指导：城市印第安人健康研究所、阿拉斯加中南部基金会、瑞典医疗中心以及华盛顿、怀俄明州、阿拉斯加、蒙大拿州和爱达荷州实践和研究网络。我们的具体目标是：（1）与我们的伙伴组织合作，修订现有的核证的排减量/变革和组织振兴方案课程，并开发满足我们的伙伴需要的新的面对面培训课程;（2）开发非同步在线培训模块，以补充我们的面对面培训;（3）从我们的伙伴组织招聘并培训24名缺乏或需要改进核证的排减量/变革和组织振兴方案技能的新学员。我们还将为华盛顿大学和其他西雅图研究和临床组织的K和T32项目的参与者提供CER/PCOR培训。我们将帮助所有受训人员开展合作性CER/PCOR试点研究; 4）与我们的合作伙伴共同开发有指导的培训经验; 5）开发一个先进的同行培训网络，该网络将侧重于观察数据，启发利益相关者和患者的观点，并在研究和实践中开发和使用以患者为中心的成果;和6）使用创新的方法，包括持续的流程改进和社会网络分析，以评估我们的计划，并努力将其转化为可在美国其他地点实施的可持续努力。我们的总体目标是为以患者为中心的成果研究伙伴关系开发一个合作伙伴驱动的模型。该伙伴关系还将努力制定和开展减少健康差距的CER/PCOR研究。我们的努力将直接影响公共卫生和医疗保健系统的质量，并发展可持续的合作，以改善我们地区的医疗保健。

DESCRIPTION (provided by applicant): Healthcare systems in the US face complex questions regarding what healthcare decisions truly improve population health. To answer such questions, we need new investigators who can conduct innovative, pragmatic research on patient-centered outcomes and on the comparative effectiveness of medical treatments. These investigators must be able to implement the findings of comparative effectiveness research (CER) and patient-centered outcomes research (PCOR) in varied and complex healthcare settings. We propose to have a stakeholder-driven educational and experiential training program to prepare scientists and clinicians for conducting CER and PCOR. Our program includes a focus on community-based healthcare for American Indians and Alaska Natives, a largely underserved population. Trainees will benefit from experiential training mentored by experts in CER/PCOR at the University of Washington and also mentored by our four partners: the Urban Indian Health Institute, Southcentral Foundation of Alaska, Swedish Medical Center, and the Washington, Wyoming, Alaska, Montana, and Idaho Practice and Research Network. Our specific aims are to: 1) Collaborate with our partner organizations, revise an existing CER/PCOR curricula and develop new in-person training sessions that meet our partners' needs; 2) Develop asynchronous, online training modules that complement our in-person training; 3) Recruit and train a cadre of 24 new trainees from our partner organizations who lack or need improved CER/PCOR skills. We will also offer CER/PCOR training to participants in K and T32 programs at UW and other Seattle-based research and clinical organizations. We will help all trainees develop collaborative CER/PCOR pilot studies; 4) Develop a mentored training experience jointly with our partners; 5) Develop an advanced peer-training network that will focus on observational data, on eliciting stakeholder and patient perspectives, and on developing and using patient-centered outcomes in research and practice; and 6) Use innovative approaches, including continuous process improvement and social network analysis, to evaluate our program and strive to translate it into a sustainable effort that can be implemented in other sites across the US. Our overarching goal is to develop a partner-driven model for a Patient-Centered Outcomes Research Partnership. This Partnership will also strive to develop and conduct CER/PCOR studies that will reduce health disparities. Our effort will directly affect the quality of public health and healthcare systems and develop sustainable collaborations to improve healthcare in our region.