Comp C-Eval of Best Urologic Management for Newborns with SB

描述(申请人提供)：脊柱裂(SB)是一种严重的出生缺陷，也是最常见的神经管缺陷(NTDS)。患有脊髓脊膜膨出(MM)的婴儿通常会因SB而出现膀胱问题。这些问题，如果处理不当，可能会导致严重的肾脏损害。一种新的针对SB患儿的膀胱管理方案已经制定。本提案旨在评估脊髓脊膜膨出新生儿的膀胱治疗方案的有效性。该项目的目标是：1)为所有在SCH接受住院护理的MM新生儿实施该方案，2)评估该方案在生命的头五年预防膀胱和肾脏问题的有效性。在SCH接受脊髓脊膜膨出住院治疗的新生儿，以前没有住院过，将有资格参加。将使用医院电子和纸质医疗记录中记录的数据，在每位参与者的后续访问中收集数据。将收集有关儿童的诊断、治疗和健康结果的信息。数据分析将由研究协调委员会指导，并将确定该方案执行得如何，以及儿童出现肾脏和膀胱问题的频率。

DESCRIPTION (provided by applicant): Spina bifida (SB) is a serious birth defect, and is the most common of the neural tube defects (NTDs). Infants who have myelomeningocele (MM), a type of SB, often have bladder problems resulting from their SB. These problems, if not managed properly, can lead to serious kidney damage. A new protocol for bladder management for children with SB has been developed. This proposal is to evaluate the effectiveness of the bladder management protocol in newborn infants with myelomeningocele. The objectives of this project are: 1) To implement this protocol at for all newborns with MM receiving inpatient care at SCH, 2) To evaluate the effectiveness of the protocol in preventing bladder and kidney problems in the first five years of life. Newborn infants who are receiving inpatient care at SCH for myelomeningocele and have not been hospitalized before will be eligible to participate. Data will be collected for each participant at their follow up visits, using data recorded in the hospitl electronic and paper medical record. Information about the child's diagnosis, treatment, and health outcomes will be collected. Data analysis will be guided by the study coordinating committee, and will be to identify how well the protocol was implemented and how often children develop kidney and bladder problems.