MULTIMODAL PRECLINICAL CANCER IMAGING AND THERAPY RESEARCH SPECIALIST

多模式临床前癌症影像和治疗研究专家

基本信息

批准号：
9354417
负责人：
Walter John Akers
金额：
$ 17万
依托单位：
ST. JUDE CHILDREN'S RESEARCH HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-09-19 至 2021-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9354417
关键词：
Anatomy Animal Cancer Model Animal Diseases Animals Award Biochemical Biological Biology Biomedical Engineering Biomedical Research Cancer Biology Complex Comprehension Contrast Media Data Detection Development Diagnosis Disease Education Engineering Environment Event Faculty Foundations Funding Goals Grant Human Image Imagery Knowledge Laboratories Malignant Neoplasms Medicine Molecular Nanotechnology Optics Organism Physiology Process Radiology Specialty Research Research Training Resource Sharing Signal Transduction Specialist Technology Therapeutic Studies Translating United States National Institutes of Health Universities Veterinarians Veterinary Medicine Washington Work anticancer research bioimaging cancer imaging cancer therapy career clinical application combat experience flexibility gene therapy imaging agent imaging approach imaging detection imaging scientist improved in vivo innovation medical schools member minimally invasive molecular imaging multimodality novel optical imaging pre-clinical programs theranostics tumor immunology

项目摘要

Project Summary Earning a doctorate and practicing veterinary medicine equipped Dr. Akers with knowledge in anatomy, physiology and diagnosis and treatment of animal diseases. He sought to further advance my research training by completing a biomedical engineering education emphasizing optical contrast agents and biomedical imaging. The complex interplay of signaling events in cancer biology is multidimensional, requiring a broad and flexible comprehension in approaching molecular imaging of cancer. Dr. Akers' career goal is to combine his education and experience as veterinarian and biological imaging scientist to combat cancer and other diseases through developing novel preclinical and translational molecular imaging approaches and improving our ability to diagnose, stage and treat disease processes. His work at Washington University is achieving this goal through development of new molecular imaging agents and detection strategies to illuminate biochemical and cellular events in vivo using non-invasive or minimally invasive detection technologies. His experience with many animal models of cancer and expertise in optical and multimodal molecular imaging has opened opportunities for innovative and collaborative biomedical research across disparate fields including tumor immunology, gene therapy and theranostic nanotechnology. Dr. Akers has therefore driven himself, through multiple collaborative studies, becoming an expert in cancer biology, animal and human. As the Assistant Director of Optical Imaging Shared Resource (OISR) and faculty member in the Optical Radiology Laboratory (ORL), he provides specialized expertise to many research programs at Washington University School of Medicine. By enabling him to continue research without disruption from inevitable changes grant funding, the NIH Specialist Award will provide continuity and autonomy to develop new imaging strategies to better accomplish the goals of funded projects and acquire preliminary data to support new research directions in cancer imaging and therapy, accelerating the Washington University School of Medicine cancer research enterprise.

项目摘要获得博士学位和实践兽医医学，为阿克斯博士提供了解剖学知识，动物疾病的生理，诊断和治疗。他试图进一步推进我的研究培训通过完成强调光学对比剂和生物医学成像的生物医学工程教育。癌症生物学中信号事件的复杂相互作用是多维的，需要广泛而灵活接近癌症分子成像的理解。阿克斯博士的职业目标是结合他的教育以及作为兽医和生物成像科学家的经验，可以通过开发新颖的临床前和翻译分子成像方法，并提高我们的能力诊断，阶段和治疗疾病过程。他在华盛顿大学的工作正在实现这一目标开发新的分子成像剂和检测策略，以阐明生化和细胞使用非侵入性或微创检测技术在体内事件。他与许多动物的经历癌症和多模式分子成像方面的癌症模型和专业知识为跨不同领域的创新和协作生物医学研究，包括肿瘤免疫学，基因治疗和治疗纳米技术。因此，阿克斯博士通过多次合作驱使自己研究，成为癌症生物学，动物和人类的专家。作为光学成像的助理主管他提供的光放射学实验室（ORL）的共享资源（OISR）和教师提供华盛顿大学医学院许多研究计划的专业知识。通过使他能够为了继续研究而不会受到不可避免的变更赠款资金的干扰，NIH专业奖将提供连续性和自主权来制定新的成像策略，以更好地实现资助的目标项目并获取初步数据，以支持癌症成像和治疗中的新研究方向，加速华盛顿大学医学院癌症研究企业。