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MULTIMODAL PRECLINICAL CANCER IMAGING AND THERAPY RESEARCH SPECIALIST

多模式临床前癌症影像和治疗研究专家

基本信息

批准号：
9762878
负责人：
Walter John Akers
金额：
$ 17万
依托单位：
ST. JUDE CHILDREN'S RESEARCH HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-09-19 至 2021-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9762878
关键词：
Anatomy Animal Cancer Model Animal Diseases Animals Award Biochemical Biological Biology Biomedical Engineering Biomedical Research Cancer Biology Complex Comprehension Contrast Media Data Detection Development Diagnosis Disease Education Engineering Environment Event Faculty Foundations Funding Goals Grant Human Image Imagery Knowledge Laboratories Malignant Neoplasms Medicine Molecular Nanotechnology Optics Organism Physiology Process Radiology Specialty Research Research Training Resource Sharing Signal Transduction Specialist Technology Therapeutic Studies Translating United States National Institutes of Health Universities Veterinarians Veterinary Medicine Washington Work anticancer research bioimaging cancer imaging cancer therapy career clinical application combat experience flexibility gene therapy imaging agent imaging approach imaging detection imaging scientist improved in vivo innovation medical schools member minimally invasive molecular imaging multimodality novel optical imaging pre-clinical programs theranostics tumor immunology

项目摘要

Project Summary Earning a doctorate and practicing veterinary medicine equipped Dr. Akers with knowledge in anatomy, physiology and diagnosis and treatment of animal diseases. He sought to further advance my research training by completing a biomedical engineering education emphasizing optical contrast agents and biomedical imaging. The complex interplay of signaling events in cancer biology is multidimensional, requiring a broad and flexible comprehension in approaching molecular imaging of cancer. Dr. Akers' career goal is to combine his education and experience as veterinarian and biological imaging scientist to combat cancer and other diseases through developing novel preclinical and translational molecular imaging approaches and improving our ability to diagnose, stage and treat disease processes. His work at Washington University is achieving this goal through development of new molecular imaging agents and detection strategies to illuminate biochemical and cellular events in vivo using non-invasive or minimally invasive detection technologies. His experience with many animal models of cancer and expertise in optical and multimodal molecular imaging has opened opportunities for innovative and collaborative biomedical research across disparate fields including tumor immunology, gene therapy and theranostic nanotechnology. Dr. Akers has therefore driven himself, through multiple collaborative studies, becoming an expert in cancer biology, animal and human. As the Assistant Director of Optical Imaging Shared Resource (OISR) and faculty member in the Optical Radiology Laboratory (ORL), he provides specialized expertise to many research programs at Washington University School of Medicine. By enabling him to continue research without disruption from inevitable changes grant funding, the NIH Specialist Award will provide continuity and autonomy to develop new imaging strategies to better accomplish the goals of funded projects and acquire preliminary data to support new research directions in cancer imaging and therapy, accelerating the Washington University School of Medicine cancer research enterprise.

项目摘要获得博士学位和从事兽医工作使阿克斯博士具备了解剖学知识，生理学和动物疾病的诊断和治疗。他试图进一步推进我的研究训练通过完成生物医学工程教育，强调光学造影剂和生物医学成像。癌症生物学中信号事件的复杂相互作用是多维的，需要广泛而灵活的对癌症分子成像的理解。埃克斯博士的职业目标是将他的教育联合收割机作为兽医和生物成像科学家，开发新的临床前和转化分子成像方法，提高我们的能力，诊断、分期和治疗疾病过程。他在华盛顿大学的工作就是通过开发新的分子成像剂和检测策略，使用非侵入性或微创检测技术在体内检测事件。他与许多动物相处的经验癌症模型以及光学和多模式分子成像的专业知识为跨不同领域的创新和合作生物医学研究，包括肿瘤免疫学，基因治疗和治疗诊断纳米技术。因此，埃克斯博士通过多种合作，研究，成为癌症生物学，动物和人类的专家。作为光学成像部的助理主任共享资源（OISR）和教员在光学放射学实验室（ORL），他提供在华盛顿大学医学院的许多研究项目中，他拥有专业知识。通过让他为了继续研究而不受不可避免的变化的影响，NIH专家奖将提供连续性和自主性，以制定新的成像策略，以更好地实现受资助的目标项目和获取初步数据，以支持癌症成像和治疗的新研究方向，加速了华盛顿大学医学院的癌症研究事业。