Conference and Workshop on New Frontiers in diagnosis, screening and management of inherited cancer syndromes

遗传性癌症综合征诊断、筛查和管理新领域会议和研讨会

• 批准号: 9133834
• 负责人: OLUFUNMILAYO F. OLOPADE
• 金额: $ 1万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-04-01 至 2018-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9133834
• 关键词: Address; Advisory Committees; Advocate; Area; Award; Cancer Patient; Case Based Learning; Chicago; Cities; Clinical; Collaborations; Communication; Communities; Complex; Data; Development; Diagnosis; Educational workshop; Evaluation; Faculty; Family; Family member; Gastroenterologist; Generations; Genes; Genetic; Genetic Counseling; Genetic screening method; Genome; Genomics; Goals; Gynecologist; Health Personnel; Healthcare; Inherited; International; Knowledge; Leadership; Location; Malignant Neoplasms; Manuscripts; Mentors; Minority; Nature; Nurses; Oncologist; Participant; Patient risk; Patients; Physician Assistants; Physicians; Prevention; Prevention approach; Primary Care Physician; Professional Education; Publishing; Research; Research Personnel; Risk; Risk Assessment; Schedule; Series; Surgeon; Syndrome; System; Technology; Testing; Travel; Universities; Update; Woman; base; cancer care; cancer genetics; cancer prevention; cancer risk; career; clinical care; clinical practice; evidence base; exome; exome sequencing; frontier; genetic counselor; genetic pedigree; genetic variant; genome sequencing; high risk; improved; individualized prevention; innovation; interest; learning community; lectures; member; multidisciplinary; next generation sequencing; novel; novel strategies; personalized health care; posters; public health relevance; response; screening; symposium; targeted cancer therapy

 DESCRIPTION (provided by applicant): Rapid advances in genetic and genomic technologies have revolutionized our approach to cancer risk assessment, screening, prevention and targeted cancer therapies, heralding the era of precision healthcare. The introduction of affordable next generation sequencing (NGS) testing including multi-gene panels and whole exome or genome sequencing provides a wealth of data on both rare and common genetic variants. While these technologies enable personalized cancer risk assessment and cancer prevention, they also require novel approaches to genetic counseling, interpretation of results and responsible communication of this complex information. While professional education in the technology and application of genomics to clinical care is urgently needed especially for community practitioners and trainees, it is not readily available and there are no opportunities for hands-on case based learning. To address the changing landscape and provide evidence-based professional education, we propose a unique interdisciplinary yearly conference series to highlight clinical innovations in cancer risk assessment and prevention. The format will include state-of the art lectures, panel discussions, small breakout sessions for case based learning and poster presentations. Our overall goal is to improve the quality of cancer risk assessment and precision prevention approaches by providing an interdisciplinary educational forum in which to disseminate new knowledge in translational genomics and evidence-based clinical care of high-risk patients and their at risk family members. In addition to our leadership team, a conference advisory committee (CAC) composed of external members with exceptional expertise in cancer genetics, who will advise on the conference agendas and speakers. Each year, we will feature different invited faculty who are experts in their field to provide state-of- the-art lectures and participate in panel and case discussions. At each subsequent conference, we will address our specific aims by disseminating updates at the cutting edge of research and clinical developments in the field. To develop a learning community, we will curate Pedigrees with accompanying clinical information submitted by workshop participants and publish an annual conference Proceedings. Our target audience includes interdisciplinary health care providers for cancer patients (oncologists, gastroenterologists, gynecologists, primary care physicians and surgeons), nurses, physician assistants and genetic counselors from community and academic practices. By offering merit- and need-based travel awards, we will provide special opportunities for trainees, junior investigators, women and minorities to participate fully in the workshops and publish with senior mentors. The locations will alternate between downtown Chicago (2016, 2018 and 2020) and City of Hope in Duarte, CA (2017 and 2019). By tracking a number of metrics and due to the dynamic nature of the emerging field of Precision Healthcare, we will alter our conference agenda to accommodate new developments and remain up-to-date and relevant to clinical practice.

 描述(申请人提供)：基因和基因组技术的快速发展彻底改变了我们对癌症风险评估、筛查、预防和有针对性的癌症治疗的方法，预示着精准医疗时代的到来。负担得起的下一代测序(NGS)测试的引入，包括多基因面板和整个外显子组或基因组测序，提供了关于稀有和常见遗传变异的丰富数据。虽然这些技术能够实现个性化的癌症风险评估和癌症预防，但它们也需要新的方法来进行遗传咨询、结果解释和对这些复杂信息进行负责任的沟通。虽然迫切需要基因组学技术和临床护理应用方面的专业教育，特别是对社区从业者和受训人员，但这种教育并不容易获得，也没有机会进行基于案例的实践学习。为了应对不断变化的形势并提供以证据为基础的专业教育，我们提出了一个独特的跨学科年度会议系列，以突出癌症风险评估和预防方面的临床创新。这种形式将包括最先进的讲座、小组讨论、基于案例的学习的小型分组会议和海报演示。我们的总体目标是通过提供一个跨学科的教育论坛，在其中传播高危患者及其高危家庭成员的翻译基因组学和循证临床护理方面的新知识，从而提高癌症风险评估和精确预防方法的质量。除了我们的领导团队，会议咨询委员会(CAC)由在癌症遗传学方面拥有非凡专业知识的外部成员组成，他们将就会议议程和演讲者提供建议。每年，我们都会有不同的特邀教师，他们是各自领域的专家，提供最先进的讲座，并参与小组和案例讨论。在随后的每一次会议上，我们将通过传播该领域研究和临床发展的最新进展来解决我们的具体目标。为了建立一个学习社区，我们将根据研讨会参与者提交的临床信息整理家谱，并出版年度会议论文集。我们的目标受众包括为癌症患者提供跨学科保健服务的人员(肿瘤学家、胃肠病专家、妇科医生、初级保健医生和外科医生)、护士、医生助理以及来自社区和学术实践的遗传咨询师。通过提供基于功绩和需要的旅行奖励，我们将为受训人员、初级调查人员、妇女和少数族裔提供特殊机会，让他们充分参与研讨会并与高级导师一起出版。地点将在芝加哥市中心(2016年、2018年和2020年)和加利福尼亚州杜阿尔特的希望之城(2017年和2019年)之间交替。通过跟踪一系列指标，并考虑到精密医疗这一新兴领域的动态特性，我们将改变会议议程以适应新的发展，并保持与临床实践相关的最新情况。