Clinical and Translational Science Award

临床和转化科学奖

• 批准号: 9309130
• 负责人: Muredach P Reilly
• 金额: $ 934.07万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-01 至 2021-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9309130
• 关键词: Abbreviations; Academic Medical Centers; Achievement; Applications Grants; Area; Award; Biomedical Research; Clinical; Clinical Investigator; Clinical Research; Clinical Sciences; Clinical and Translational Science Awards; Collaborations; Communities; Consultations; Dental; Education; Educational Status; Ensure; Environment; Ethics; Evolution; Faculty; Freedom; Funding; Gifts; Goals; Grant; Health; Health Professional; Hospitals; Individual; Information Dissemination; Information Technology; Inpatients; Institutes; Investigation; Knowledge; Laboratories; Left; Link; Medical Research; Medical center; Medicine; Methodology; Mission; National Center for Research Resources; New York; Nurses; Nursing Research; Outpatients; Participant; Patients; Physicians; Precision Medicine Initiative; Presbyterian Church; Privacy; Process; Provider; Public Health Schools; Recording of previous events; Recruitment Activity; Research; Research Infrastructure; Research Personnel; Research Support; Research Training; Resources; Rewards; School Nursing; Science; Scientist; Source; Speed; Structure; Students; Surgeon; System; Testing; Text; Therapeutic; Time; Training; Training Support; Translational Research; Trust; Trustees; United States National Institutes of Health; Universities; Vision; Washington; base; career; clinical care; college; cost; improved; innovation; insight; interest; member; multidisciplinary; next generation; novel; novel therapeutics; precision medicine; programs; senior faculty; skills; success; tool; translational scientist; web site

Contact PD/PI: GINSBERG, HENRY N OVERALL ABSTRACT Our CTSA Hub is situated in the Irving Institute for Clinical and Translational Research (Irving Institute) of Columbia University (CU), and based at the CU Medical Center (CUMC) in Northern Manhattan (NM). The CU College of Physicians and Surgeons (P&S), Mailman School of Public Health (MSPH), College of Dental Medicine (CDM), and School of Nursing (SON) are all at CUMC together with major components of New York Presbyterian Hospital (NYP) and the New York State Psychiatric Institute (NYSPI). The vision of the Irving Institute is: 1) to transform the culture of biomedical research enabling CUMC investigators to develop new treatments faster and deliver those treatments to patients more efficiently, effectively, and safely than ever before; 2) to utilize medical research advances to benefit patients and the community, converting knowledge into practice; and 3) to recruit, train, support and nurture the next generation of clinical and translational investigators in multi- and interdisciplinary team science environments. Since first receiving CTSA funding in 2006, we embraced a vision that would impact maximally on a) individuals, particularly junior faculty and trainees, b) groups of faculty and trainees working in common areas of interest but often in relative isolation, and 3) the institutional culture. We believed that this bottom-up approach was necessary if we were to move CUMC from a system that rewarded individual effort more than the achievements of groups. After nine years, we are certain that we have changed the environment significantly, and that CUMC and NYP both understand that multidisciplinary team efforts are essential for success in this era of greater complexity both in science and in clinical care. Additionally, we all have come to understand that only by engaging our patients early in the research process, particularly those individuals in the communities of Northern Manhattan (NM), will we gain their trust and enthusiasm, two keys to their participation in the revolution generated by Precision Medicine. Our aim is to expand, enhance, and improve the Irving Institute's CTSA Hub, to ensure that we create an outstanding environment where junior and senior faculty, trainees, clinical research coordinators, nurses, support staff, and patients, particularly members of the underserved and underrepresent communities of NM are all engaged in, and benefit from, our efforts to meet the exciting and unique opportunities afforded by the CU/NYP Precision Medicine Initiative and the extraordinary advancements in information technologies, `omics', and therapeutic possibilities. Innovations and achievements at our Hub will be disseminated for the benefit of our local neighboring Hubs and the CTSA Hub Network. Project Summary/Abstract Page 162 Contact PD/PI: GINSBERG, HENRY N Narrative The Clinical and Translational Science Award (CTSA) allows Columbia University to support novel programs whose goal is to speed the transition from scientific discoveries made in the laboratory toward new therapies. We will conduct and support research, training, health information dissemination, and other programs with respect to translational science. We will facilitate the training of scholars from diverse backgrounds underrepresented in translational science who are knowledgeable about and available to focus on translational science later in their careers.

联系人 PD/PI：GINSBERG, HENRY N 总体摘要 我们的 CTSA 中心位于美国欧文临床和转化研究所（欧文研究所） 哥伦比亚大学 (CU)，位于曼哈顿北部 (NM) 的 CU 医学中心 (CUMC)。 CU 内外科医学院 (P&S)、梅尔曼公共卫生学院 (MSPH)、牙科学院 医学院 (CDM) 和护理学院 (SON) 均位于 CUMC 以及纽约的主要组成部分 长老会医院 (NYP) 和纽约州精神病研究所 (NYSPI)。欧文的愿景 研究所的目标是： 1) 转变生物医学研究文化，使 CUMC 研究人员能够开发新的 治疗速度更快，并比以往更高效、有效和安全地为患者提供治疗 前; 2）利用医学研究进展造福患者和社区，转化知识 付诸实践； 3) 招募、培训、支持和培养下一代临床和转化人才 多学科和跨学科团队科学环境中的研究人员。自首次获得 CTSA 资助以来 2006 年，我们提出了一个愿景，该愿景将最大程度地影响 a) 个人，特别是初级教师和 受训者，b) 在共同感兴趣的领域工作但通常相对孤立的教师和受训者群体， 3）制度文化。我们相信，如果我们要采取行动，这种自下而上的方法是必要的。 CUMC 的体系对个人努力的奖励多于对团体成就的奖励。九年后， 我们确信我们已经显着改变了环境，并且 CUMC 和 NYP 都明白 在这个科学和技术都更加复杂的时代，多学科团队的努力对于成功至关重要 在临床护理中。此外，我们都已经认识到，只有尽早让患者参与进来 研究过程，特别是那些生活在北曼哈顿 (NM) 社区的个人，我们将获得 他们的信任和热情是他们参与精准医学革命的两个关键。 我们的目标是扩大、增强和改进欧文研究所的 CTSA 中心，以确保我们创建一个 优秀的环境，初级和高级教师、实习生、临床研究协调员、护士、 支持人员和患者，特别是新墨西哥州服务不足和代表性不足的社区的成员 我们所有人都参与并受益于我们的努力，以迎接由 CU/NYP 精准医学计划以及信息技术、“组学”、 和治疗的可能性。我们中心的创新和成就将被传播，造福于 我们当地的邻近枢纽和 CTSA 枢纽网络。 项目总结/摘要第 162 页 联系人 PD/PI：GINSBERG, HENRY N 叙述 临床和转化科学奖 (CTSA) 允许哥伦比亚大学支持新颖的项目 其目标是加速从实验室科学发现向新疗法的转变。 我们将开展并支持研究、培训、健康信息传播和其他项目 尊重转化科学。我们将促进来自不同背景的学者的培训 在转化科学领域中代表性不足，但他们了解并能够专注于转化 在他们的职业生涯后期从事科学。