Clinical and Translational Science Award

临床和转化科学奖

基本信息

  • 批准号:
    9309130
  • 负责人:
  • 金额:
    $ 934.07万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2016
  • 资助国家:
    美国
  • 起止时间:
    2016-07-01 至 2021-05-31
  • 项目状态:
    已结题

项目摘要

Contact PD/PI: GINSBERG, HENRY N OVERALL ABSTRACT Our CTSA Hub is situated in the Irving Institute for Clinical and Translational Research (Irving Institute) of Columbia University (CU), and based at the CU Medical Center (CUMC) in Northern Manhattan (NM). The CU College of Physicians and Surgeons (P&S), Mailman School of Public Health (MSPH), College of Dental Medicine (CDM), and School of Nursing (SON) are all at CUMC together with major components of New York Presbyterian Hospital (NYP) and the New York State Psychiatric Institute (NYSPI). The vision of the Irving Institute is: 1) to transform the culture of biomedical research enabling CUMC investigators to develop new treatments faster and deliver those treatments to patients more efficiently, effectively, and safely than ever before; 2) to utilize medical research advances to benefit patients and the community, converting knowledge into practice; and 3) to recruit, train, support and nurture the next generation of clinical and translational investigators in multi- and interdisciplinary team science environments. Since first receiving CTSA funding in 2006, we embraced a vision that would impact maximally on a) individuals, particularly junior faculty and trainees, b) groups of faculty and trainees working in common areas of interest but often in relative isolation, and 3) the institutional culture. We believed that this bottom-up approach was necessary if we were to move CUMC from a system that rewarded individual effort more than the achievements of groups. After nine years, we are certain that we have changed the environment significantly, and that CUMC and NYP both understand that multidisciplinary team efforts are essential for success in this era of greater complexity both in science and in clinical care. Additionally, we all have come to understand that only by engaging our patients early in the research process, particularly those individuals in the communities of Northern Manhattan (NM), will we gain their trust and enthusiasm, two keys to their participation in the revolution generated by Precision Medicine. Our aim is to expand, enhance, and improve the Irving Institute's CTSA Hub, to ensure that we create an outstanding environment where junior and senior faculty, trainees, clinical research coordinators, nurses, support staff, and patients, particularly members of the underserved and underrepresent communities of NM are all engaged in, and benefit from, our efforts to meet the exciting and unique opportunities afforded by the CU/NYP Precision Medicine Initiative and the extraordinary advancements in information technologies, `omics', and therapeutic possibilities. Innovations and achievements at our Hub will be disseminated for the benefit of our local neighboring Hubs and the CTSA Hub Network. Project Summary/Abstract Page 162 Contact PD/PI: GINSBERG, HENRY N Narrative The Clinical and Translational Science Award (CTSA) allows Columbia University to support novel programs whose goal is to speed the transition from scientific discoveries made in the laboratory toward new therapies. We will conduct and support research, training, health information dissemination, and other programs with respect to translational science. We will facilitate the training of scholars from diverse backgrounds underrepresented in translational science who are knowledgeable about and available to focus on translational science later in their careers.
联系PD/PI:金斯伯格,Henry N 总体摘要 我们的CTSA中心位于欧文临床与翻译研究所(欧文研究所) 总部设在曼哈顿北部的科罗拉多州立大学医学中心(CUMC)。CU 内科和外科医学院(P&S)、梅尔曼公共卫生学院(MSPH)、牙科学院 医学院(CDM)和护理学院(SON)都与纽约的主要组成部分一起在CUMC 长老会医院(NYP)和纽约州精神病研究所(NYSPI)。欧文的愿景 研究所是:1)转变生物医学研究的文化,使CUMC的研究人员能够开发新的 更快的治疗,为患者提供比以往更高效、有效和安全的治疗 以前;2)利用医学研究进展造福患者和社区,转化知识 实施;以及3)招聘、培训、支持和培育下一代临床和翻译人员 多学科和跨学科团队科学环境中的研究人员。自#年首次获得CTSA资助以来 2006年,我们的愿景将最大限度地影响a)个人,特别是初级教职员工和 受训人员,b)在共同感兴趣的领域工作但往往相对孤立的教职员工和受训人员团体, 3)制度文化。我们认为,如果我们要采取行动,这种自下而上的方法是必要的。 CUMC来自一种奖励个人努力多于团队成就的制度。九年后, 我们确信,我们已经显著改变了环境,CUMC和NYP都理解 多学科团队的努力对于在这个科学和技术更加复杂的时代取得成功至关重要 在临床护理方面。此外,我们都已经认识到,只有在早期接触我们的患者 研究过程,特别是那些在北曼哈顿(新墨西哥州)社区的个人,我们将获得 他们的信任和热情,是他们参与精密医疗产生的革命的两个关键。 我们的目标是扩大、增强和改进欧文研究所的CTSA中心,以确保我们创建 初级和高级教员、实习生、临床研究协调员、护士、 支持工作人员和患者,特别是NM社区中服务不足和代表性不足的成员 我们都参与并受惠于我们的努力,以迎接 CU/NYP精密医学倡议和信息技术的非凡进步,《组学》, 和治疗的可能性。我们中心的创新和成就将传播,造福于 我们当地的邻近枢纽和CTSA枢纽网络。 项目摘要/摘要页162 联系PD/PI:金斯伯格,Henry N 叙述性 临床和转化科学奖(CTSA)允许哥伦比亚大学支持新项目 其目标是加快从实验室的科学发现向新疗法的过渡。 我们将开展和支持研究、培训、卫生信息传播等项目 尊重翻译科学。我们将为不同背景的学者的培训提供便利 在翻译科学中的代表性不足,他们对翻译有了解并可以专注于翻译 在他们职业生涯的后期从事科学研究。

项目成果

期刊论文数量(0)
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会议论文数量(0)
专利数量(0)

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Muredach P Reilly其他文献

Single-cell multimodal profiling of monocytes reveals diverse phenotypes and alterations linked to cardiovascular disease risks
单核细胞的单细胞多模式分析揭示了与心血管疾病风险相关的多种表型和变化
  • DOI:
    10.1101/2024.02.18.580913
  • 发表时间:
    2024
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Alexander C. Bashore;Chenyi Xue;Eunyoung Kim;Hanying Yan;Lucie Y. Zhu;Huize Pan;Michael D Kissner;Leila S Ross;Hanrui Zhang;Mingyao Li;Muredach P Reilly
  • 通讯作者:
    Muredach P Reilly
1008-184 The effects of pravastatin and atorvastatin on markers of oxidant stress in vivo
  • DOI:
    10.1016/s0735-1097(04)91877-3
  • 发表时间:
    2004-03-03
  • 期刊:
  • 影响因子:
  • 作者:
    Bonnie Ky;Megan L Wolfe;Anne Burke;Philippe O Szapary;Muredach P Reilly;Jennifer B Dykhouse;Leanne T Bloedon;Garret A FitzGerald;Daniel J Rader
  • 通讯作者:
    Daniel J Rader

Muredach P Reilly的其他文献

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{{ truncateString('Muredach P Reilly', 18)}}的其他基金

Smooth muscle cell-derived cell fates and cellular interactions in atherosclerotic plaque stability in disease progression and regression.
平滑肌细胞衍生的细胞命运和细胞相互作用在疾病进展和消退中动脉粥样硬化斑块的稳定性。
  • 批准号:
    10567844
  • 财政年份:
    2023
  • 资助金额:
    $ 934.07万
  • 项目类别:
Identification of smooth muscle cell genes causal in atherosclerotic plaque stability and cardiovascular disease risk
鉴定导致动脉粥样硬化斑块稳定性和心血管疾病风险的平滑肌细胞基因
  • 批准号:
    10720225
  • 财政年份:
    2023
  • 资助金额:
    $ 934.07万
  • 项目类别:
Clinical and Translational Science Award
临床和转化科学奖
  • 批准号:
    10674531
  • 财政年份:
    2022
  • 资助金额:
    $ 934.07万
  • 项目类别:
Human LincRNAs in Macrophage Biology and Related Cardiometabolic Diseases
巨噬细胞生物学和相关心脏代谢疾病中的人类 LincRNA
  • 批准号:
    9402855
  • 财政年份:
    2017
  • 资助金额:
    $ 934.07万
  • 项目类别:
Human LincRNAs in Macrophage Biology and Related Cardiometabolic Diseases
巨噬细胞生物学和相关心脏代谢疾病中的人类 LincRNA
  • 批准号:
    9983136
  • 财政年份:
    2017
  • 资助金额:
    $ 934.07万
  • 项目类别:
Human LincRNAs in Macrophage Biology and Related Cardiometabolic Diseases
巨噬细胞生物学和相关心脏代谢疾病中的人类 LincRNA
  • 批准号:
    9531432
  • 财政年份:
    2017
  • 资助金额:
    $ 934.07万
  • 项目类别:
Clinical and Translational Science Award
临床和转化科学奖
  • 批准号:
    10349079
  • 财政年份:
    2016
  • 资助金额:
    $ 934.07万
  • 项目类别:
Clinical and Translational Science Award
临床和转化科学奖
  • 批准号:
    10439923
  • 财政年份:
    2016
  • 资助金额:
    $ 934.07万
  • 项目类别:
Clinical and Translational Science Award
临床和转化科学奖
  • 批准号:
    10199125
  • 财政年份:
    2016
  • 资助金额:
    $ 934.07万
  • 项目类别:
Clinical and Translational Science Award
临床和转化科学奖
  • 批准号:
    9932779
  • 财政年份:
    2016
  • 资助金额:
    $ 934.07万
  • 项目类别:

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  • 批准号:
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