Clinical and Translational Science Award
临床和转化科学奖
基本信息
- 批准号:9309130
- 负责人:
- 金额:$ 934.07万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2016
- 资助国家:美国
- 起止时间:2016-07-01 至 2021-05-31
- 项目状态:已结题
- 来源:
- 关键词:AbbreviationsAcademic Medical CentersAchievementApplications GrantsAreaAwardBiomedical ResearchClinicalClinical InvestigatorClinical ResearchClinical SciencesClinical and Translational Science AwardsCollaborationsCommunitiesConsultationsDentalEducationEducational StatusEnsureEnvironmentEthicsEvolutionFacultyFreedomFundingGiftsGoalsGrantHealthHealth ProfessionalHospitalsIndividualInformation DisseminationInformation TechnologyInpatientsInstitutesInvestigationKnowledgeLaboratoriesLeftLinkMedical ResearchMedical centerMedicineMethodologyMissionNational Center for Research ResourcesNew YorkNursesNursing ResearchOutpatientsParticipantPatientsPhysiciansPrecision Medicine InitiativePresbyterian ChurchPrivacyProcessProviderPublic Health SchoolsRecording of previous eventsRecruitment ActivityResearchResearch InfrastructureResearch PersonnelResearch SupportResearch TrainingResourcesRewardsSchool NursingScienceScientistSourceSpeedStructureStudentsSurgeonSystemTestingTextTherapeuticTimeTrainingTraining SupportTranslational ResearchTrustTrusteesUnited States National Institutes of HealthUniversitiesVisionWashingtonbasecareerclinical carecollegecostimprovedinnovationinsightinterestmembermultidisciplinarynext generationnovelnovel therapeuticsprecision medicineprogramssenior facultyskillssuccesstooltranslational scientistweb site
项目摘要
Contact PD/PI: GINSBERG, HENRY N
OVERALL ABSTRACT
Our CTSA Hub is situated in the Irving Institute for Clinical and Translational Research (Irving Institute) of
Columbia University (CU), and based at the CU Medical Center (CUMC) in Northern Manhattan (NM). The CU
College of Physicians and Surgeons (P&S), Mailman School of Public Health (MSPH), College of Dental
Medicine (CDM), and School of Nursing (SON) are all at CUMC together with major components of New York
Presbyterian Hospital (NYP) and the New York State Psychiatric Institute (NYSPI). The vision of the Irving
Institute is: 1) to transform the culture of biomedical research enabling CUMC investigators to develop new
treatments faster and deliver those treatments to patients more efficiently, effectively, and safely than ever
before; 2) to utilize medical research advances to benefit patients and the community, converting knowledge
into practice; and 3) to recruit, train, support and nurture the next generation of clinical and translational
investigators in multi- and interdisciplinary team science environments. Since first receiving CTSA funding in
2006, we embraced a vision that would impact maximally on a) individuals, particularly junior faculty and
trainees, b) groups of faculty and trainees working in common areas of interest but often in relative isolation,
and 3) the institutional culture. We believed that this bottom-up approach was necessary if we were to move
CUMC from a system that rewarded individual effort more than the achievements of groups. After nine years,
we are certain that we have changed the environment significantly, and that CUMC and NYP both understand
that multidisciplinary team efforts are essential for success in this era of greater complexity both in science and
in clinical care. Additionally, we all have come to understand that only by engaging our patients early in the
research process, particularly those individuals in the communities of Northern Manhattan (NM), will we gain
their trust and enthusiasm, two keys to their participation in the revolution generated by Precision Medicine.
Our aim is to expand, enhance, and improve the Irving Institute's CTSA Hub, to ensure that we create an
outstanding environment where junior and senior faculty, trainees, clinical research coordinators, nurses,
support staff, and patients, particularly members of the underserved and underrepresent communities of NM
are all engaged in, and benefit from, our efforts to meet the exciting and unique opportunities afforded by the
CU/NYP Precision Medicine Initiative and the extraordinary advancements in information technologies, `omics',
and therapeutic possibilities. Innovations and achievements at our Hub will be disseminated for the benefit of
our local neighboring Hubs and the CTSA Hub Network.
Project Summary/Abstract Page 162
Contact PD/PI: GINSBERG, HENRY N
Narrative
The Clinical and Translational Science Award (CTSA) allows Columbia University to support novel programs
whose goal is to speed the transition from scientific discoveries made in the laboratory toward new therapies.
We will conduct and support research, training, health information dissemination, and other programs with
respect to translational science. We will facilitate the training of scholars from diverse backgrounds
underrepresented in translational science who are knowledgeable about and available to focus on translational
science later in their careers.
联系PD/PI:GINSBERG,亨利N
总体摘要
我们的CTSA中心位于美国的欧文临床和转化研究所(欧文研究所)。
哥伦比亚大学(CU),总部设在北方曼哈顿(NM)的CU医学中心(CDC)。所述CU
内科医生和外科医生学院(P&S),梅尔曼公共卫生学院(MSPH),牙科学院
医学院(CDM)和护理学院(SON)都在纽约大学,与纽约的主要组成部分一起
长老会医院(NYP)和纽约州精神病研究所(NYSPI)。欧文的愿景
研究所的目标是:1)转变生物医学研究的文化,使研究人员能够开发新的
治疗速度更快,并比以往任何时候都更有效,更安全地将这些治疗提供给患者
2)利用医学研究进展造福患者和社区,将知识转化为
3)招募、培训、支持和培养下一代临床和翻译人员
多学科和跨学科团队科学环境中的研究人员。自2011年首次获得CTSA资助以来,
2006年,我们接受了一个愿景,这将最大限度地影响a)个人,特别是初级教师,
学员,B)在共同感兴趣的领域工作但通常相对孤立的教师和学员群体,
三是制度文化。我们认为,如果我们要采取行动,
CUMC来自一个奖励个人努力多于团体成就的制度。九年后,
我们确信,我们已经显著地改变了环境,而且美国国防部和纽约警察局都明白,
多学科团队的努力对于在这个科学和技术都更加复杂的时代取得成功至关重要,
在临床护理中。此外,我们都已经明白,只有让我们的病人尽早参与,
研究过程中,特别是那些在北方曼哈顿(NM)社区的个人,我们将获得
他们的信任和热情,这是他们参与精准医学革命的两个关键。
我们的目标是扩大,增强和改善欧文研究所的CTSA中心,以确保我们创造一个
优秀的环境,初级和高级教师,学员,临床研究协调员,护士,
支持人员和患者,特别是服务不足和代表性不足的NM社区的成员
我们都参与并受益于我们的努力,以满足令人兴奋的和独特的机会,
CU/NYP精准医学倡议和信息技术、“组学”、
和治疗的可能性。我们中心的创新和成就将被传播,
我们当地的邻近枢纽和CTSA枢纽网络。
项目摘要/摘要第162页
联系PD/PI:GINSBERG,亨利N
叙事
临床和转化科学奖(CTSA)允许哥伦比亚大学支持新的项目
其目标是加速从实验室中的科学发现向新疗法的过渡。
我们将开展和支持研究、培训、卫生信息传播和其他项目,
尊重转化科学。我们将促进来自不同背景的学者的培训
在翻译科学中代表性不足,他们了解并可以专注于翻译
科学在他们的职业生涯中。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Muredach P Reilly其他文献
Single-cell multimodal profiling of monocytes reveals diverse phenotypes and alterations linked to cardiovascular disease risks
单核细胞的单细胞多模式分析揭示了与心血管疾病风险相关的多种表型和变化
- DOI:
10.1101/2024.02.18.580913 - 发表时间:
2024 - 期刊:
- 影响因子:0
- 作者:
Alexander C. Bashore;Chenyi Xue;Eunyoung Kim;Hanying Yan;Lucie Y. Zhu;Huize Pan;Michael D Kissner;Leila S Ross;Hanrui Zhang;Mingyao Li;Muredach P Reilly - 通讯作者:
Muredach P Reilly
1008-184 The effects of pravastatin and atorvastatin on markers of oxidant stress in vivo
- DOI:
10.1016/s0735-1097(04)91877-3 - 发表时间:
2004-03-03 - 期刊:
- 影响因子:
- 作者:
Bonnie Ky;Megan L Wolfe;Anne Burke;Philippe O Szapary;Muredach P Reilly;Jennifer B Dykhouse;Leanne T Bloedon;Garret A FitzGerald;Daniel J Rader - 通讯作者:
Daniel J Rader
Muredach P Reilly的其他文献
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{{ truncateString('Muredach P Reilly', 18)}}的其他基金
Smooth muscle cell-derived cell fates and cellular interactions in atherosclerotic plaque stability in disease progression and regression.
平滑肌细胞衍生的细胞命运和细胞相互作用在疾病进展和消退中动脉粥样硬化斑块的稳定性。
- 批准号:
10567844 - 财政年份:2023
- 资助金额:
$ 934.07万 - 项目类别:
Identification of smooth muscle cell genes causal in atherosclerotic plaque stability and cardiovascular disease risk
鉴定导致动脉粥样硬化斑块稳定性和心血管疾病风险的平滑肌细胞基因
- 批准号:
10720225 - 财政年份:2023
- 资助金额:
$ 934.07万 - 项目类别:
Human LincRNAs in Macrophage Biology and Related Cardiometabolic Diseases
巨噬细胞生物学和相关心脏代谢疾病中的人类 LincRNA
- 批准号:
9402855 - 财政年份:2017
- 资助金额:
$ 934.07万 - 项目类别:
Human LincRNAs in Macrophage Biology and Related Cardiometabolic Diseases
巨噬细胞生物学和相关心脏代谢疾病中的人类 LincRNA
- 批准号:
9983136 - 财政年份:2017
- 资助金额:
$ 934.07万 - 项目类别:
Human LincRNAs in Macrophage Biology and Related Cardiometabolic Diseases
巨噬细胞生物学和相关心脏代谢疾病中的人类 LincRNA
- 批准号:
9531432 - 财政年份:2017
- 资助金额:
$ 934.07万 - 项目类别:
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