Clinical and Translational Science Award

联系PD/PI：Reilly，Muredach P 总体：项目总结/摘要 我们的使命是通过以下方式改善当地和全国患者和社区的健康 临床和转化研究的创新。我们的战略愿景是促进临床和 转化科学（T0-T4），与我们的合作伙伴和利益相关者协同，并整合我们的活动 中心和整个国家临床和转化科学奖（CTSA）计划。为了实现这一愿景， 我们将建立在我们强大的既定记录（例如，在精准医学方面），我们的计划是解决重要的 公共卫生挑战（例如，COVID-19大流行、阿片类药物危机）和解决关键障碍（例如， 创新使用电子健康记录的研究，临床试验设计），因为我们拥抱CTSA PAR-18-940中指定的计划优先级。我们的愿景是改变我们的健康和福祉， 在纽约市的社区，国家和世界。为了实现这一目标，我们部署了我们的计划和资源， 开发、展示和传播创新， 临床和转化科学 在整个 平移谱 作为一个全面的CTSA，我们为学员，学者和 我们整个中心的调查人员，包括哥伦比亚大学，哥伦比亚大学欧文医学院 中心，纽约精神病研究所和纽约长老会医院。与此同时， 灵活和深入地解决关键的科学或机构的机会，以及主要的公共卫生需求 和差距。我们通过在多个层面实现目标来取得成功：a）持续的战略规划 包括每年举行一次务虚会，以审查业务情况并查明差距、需求和机会; B）每月交叉审查， 减少“主题”会议，以便在处理差距和机会时能够合作解决问题; 创新的评价和持续改进战略，利用参与式管理， 项目规划和执行的评估;以及d）非常成功的创新跨学科培训 和劳动力发展计划建立在团队科学的基础上。我们努力改善 个人、社区和国家层面的健康和福祉是我们战略合作的重点， 传播。因此，我们寻求不断创造和完善创新，为综合研究-和用户- 在我们的枢纽友好的翻译研究环境：利用我们整个枢纽的合作伙伴关系; 改变与我们当地社区，校园卫生系统和整个纽约州的合作; 并通过与以下机构的合作，加速创新实践和知识的双向传播， CTSA计划网络及其他。 项目摘要/摘要第221页 联系PD/PI：Reilly，Muredach P 叙事 临床和转化科学奖（CTSA）允许哥伦比亚大学支持新的项目 其目标是加速从实验室中的科学发现向新疗法的过渡。 我们将在过去良好的业绩基础上，应对重大挑战和关键障碍， research.我们将促进来自不同背景的学者的培训， 科学谁是知识渊博，并可专注于转化科学在他们的职业生涯后期。

Contact PD/PI: Reilly, Muredach P OVERALL: PROJECT SUMMARY/ABSTRACT Our mission is to improve the health of our patients and communities both locally and nationally through innovations in clinical and translational research. Our strategic vision is to catalyze all phases of clinical and translational science (T0-T4), synergize with our partners and stakeholders, and integrate activities within our hub and across the national Clinical and Translational Science Award (CTSA) Program. To achieve this vision, we will build on our strong established track-record (e.g., in precision medicine), our plans to tackle important public-health challenges (e.g., COVID-19 pandemic, the opioid crisis) and to address critical barriers (e.g., innovation in use of electronic health records for research, clinical trial designs) as we embrace the CTSA Program priorities designated in PAR-18-940. Our vision is to transform the health and wellbeing of our communities in New York City, the nation and the world. To achieve this, we deploy our programs and resources to develop, demonstrate and disseminate innovations in clinical and translational science across the full translational spectrum. As a comprehensive CTSA, we offer a broad array of support for trainees, scholars and investigators across our entire hub which includes Columbia University, the Columbia University Irving Medical Center, the New York Psychiatric Institute, and New York Presbyterian Hospital. At the same time, we move flexibly and deeply to address critical scientific or institutional opportunities as well as major public health needs and gaps. We achieve success by approaching our goals at multiple levels: a) Ongoing strategic planning including an annual retreat to review operations and identify gaps, needs and opportunities; b) Monthly cross- cutting “Theme” meetings to enable collaborative problem-solving in addressing gaps and opportunities; c) An innovative Evaluation and Continuous Improvement strategy using participatory management to integrate evaluation into program planning and execution; and d) A highly successful, innovative interdisciplinary training and workforce development program built on a foundation of team science. Central to our efforts to improve health and wellbeing at personal, community and national levels is our emphasis on strategic collaboration and dissemination. Thus, we seek to continuously create and refine innovations for an integrated research- and user- friendly translational research environment at our hub by: Harnessing partnerships across our entire hub; Transforming collaborations with our local communities, the campus health system and across New York State; And by accelerating bidirectional dissemination of innovative practices and learnings through collaborations with the CTSA Program network and beyond. Project Summary/Abstract Page 221 Contact PD/PI: Reilly, Muredach P Narrative The Clinical and Translational Science Award (CTSA) allows Columbia University to support novel programs whose goal is to speed the transition from scientific discoveries made in the laboratory toward new therapies. Building on our strong established track-record, we will tackle important challenges and critical barriers to research. We will facilitate the training of scholars from diverse backgrounds underrepresented in translational science who are knowledgeable about and available to focus on translational science later in their careers.