Dynamic exposure pathways under conditions of environmental emergencies

项目1 拟议中的德克萨斯A & M大学超级基金研究中心旨在减少人类接触 有害物质，特别是暴露于人为或人为重新分布的污染物混合物， 自然环境灾害。项目1将调查受污染沉积物的重新分布情况， 土壤和海洋沉积物是洪水和风暴等自然灾害的后果。改变 气候、人为引起的地面沉降和海平面上升增加了沿海地区的脆弱性， 世界范围内的环境灾害。拟建中心的重点是加尔维斯顿湾， 休斯顿船舶通道（GB/HSC），我们的团队在该领域有数十年的分析经验 沉积物、海洋生物组织和遗留污染物水样。GB/HSC区域 包括美国第四大都市，位于污染最严重的城市之一附近， 海洋/沿海地区，有22个列入或拟议的超级基金地点。这个地区容易发生环境灾难 如洪水、热带风暴和飓风;大风暴可能会重新分布目前 与整个海洋区域的沉积物结合，并通过 风暴潮和洪水。我们的专业知识为检验我们的核心假设奠定了坚实的基础， 表征当前沉积物和土壤污染物水平、沉积物迁移、再分布，以及 极端天气紧急事件引起的变化将确定复杂的 污染的混合物，并告知方法，以预测，应对和减轻这些暴露，以保护 受影响人口的健康。项目1对整个中心至关重要，因为它将确定污染物负荷 海洋沉积物的历史数据和新的化学分析，建立目前的背景， 在当地社区确定的重点地区的土壤中的污染物，并收集和分析样品， 在风暴事件之后。我们将与社区参与核心合作，确定关注的领域， 然后从陆地和海洋沉积物中取样土壤。我们还将获得已经收集的 样本来自广泛的州和联邦政府合作者网络，并分析所有样本， 超级基金关注的危险污染物。通过实验室研究，我们将确定 沉积物中的化合物在被输送到陆地时发生的转化。此外，我们将开发 预测飓风和洪水模型，以确定期间危险污染物动员的程度 环境紧急情况。这些模型将适用于美国和世界其他地区， 在环境紧急情况方面也存在着类似的关切， 被危险化学品污染的沉积物。与曝光科学核心合作，项目1将 对污染物进行有针对性和非有针对性的分析，并在现实条件下描述暴露特征。 环境条件此外，项目1将提供已知的实际污染物混合物， 将未知的有害污染物引入其他核心和项目，以确定其对社区的毒性和风险。

Project 1 ABSTRACT The proposed Texas A&M University Superfund Research Center aims to mitigate human exposure to hazardous substances, specifically exposure to mixtures of contaminants that are redistributed by manmade or natural environmental disasters. Project 1 will investigate the redistribution of contaminated sediments from both soils and marine sediments as a consequence of natural disasters such as floods and storms. Changing climate, human-induced land subsidence, and rising sea levels have increased the vulnerability of coastal areas to environmental disasters worldwide. The proposed Center is focused on the Galveston Bay and Houston Ship Channel (GB/HSC), an area where our group has had decades of experience analyzing sediments, tissues of marine organisms, and water samples for legacy contaminants. The GB/HSC area includes the 4th largest metropolitan city in the US and is located near one of the most contaminated marine/coastal areas, with 22 listed or proposed Superfund sites. The area is prone to environmental disasters such as floods, tropical storms, and hurricanes; large storms may redistribute contaminants that are currently bound to sediments throughout the marine area and cause widespread land deposition of contaminants via storm surge and flooding. Our expertise forms a solid foundation to test our central hypothesis that characterizing current sediment and soil contaminant levels, sediment transport, redistribution, and transformation caused by extreme weather emergency events will identify exposure pathways of complex contaminated mixtures and inform methods to predict, respond to, and mitigate these exposures to protect the health of affected populations. Project 1 is critical to the overall Center as it will determine contaminant loading of marine sediments from historical data and new chemical analyses, establish the current background of contaminants in the soils of key areas identified by local communities, and collect and analyze samples before and after storm events. We will work with the Community Engagement Core to determine areas of concern to communities and then sample soils from land and marine sediments. We will also obtain already collected samples from a wide network of State and Federal government collaborators, and analyze all samples for hazardous contaminants of concern to Superfund. Through laboratory studies, we will determine the potential transformation of compounds in sediments as they are transported to land. Furthermore, we will develop predictive hurricane and flood models to determine the extent of hazardous contaminant mobilization during environmental emergencies. These models will be adaptable to other areas in the US and worldwide where similar concerns exist with respect to environmental emergencies that involve possible redistribution of sediments contaminated with hazardous chemicals. Working with the Exposure Science Core, Project 1 will perform targeted and non-targeted analyses of contaminants and characterize exposures under realistic environmental conditions. In addition, Project 1 will provide real-world contaminant mixtures of known and unknown hazardous pollutants to other Cores and Projects to determine the toxicity and risk to communities.