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 DESCRIPTION (provided by applicant): Data provenance is key to ensuring data quality, scientific reproducibility, and tracing the lineage of data as it undergoes transformation for use n the "data-driven" research paradigm. The emerging "Big Data" resources in biomedical research and clinical care domains have highlighted multiple computational challenges to develop a scalable and high performance provenance analysis engine. These computational challenges include semantic heterogeneity across provenance information generated from disparate sources (variety), lack of scalable provenance analytical algorithms that can keep pace with large volume of data generated at a rapid velocity. Using the new PROV representation standard recommended the W3C, which is the standard body for Web technologies, together with distributed cloud computing technologies we propose to develop a highly scalable data source agnostic provenance engine. To address the lack of appropriate provenance analytical operations required to develop this provenance engine over the PROV representation model, we will follow a three-phase approach: (1) we will first develop a new algebraic graph framework for analyzing provenance graphs conforming to the PROV standard, (2) in the second phase we will use the insights from the systematic characterization of provenance analysis operations to define distributed algorithms for implementation over cloud computing technologies, and (3) in the final step, we will implement the provenance engine that will support three fundamental provenance functions of (a) scientific reproducibility, (b) data quality assurance, and (c) trust computation. The resulting provenance engine will potentially transform the use of provenance in biomedical "Big Data" exploration and analysis techniques in the increasing number of data repositories such as the National Sleep Research Resource for accelerating data-driven research in disease mechanisms.
期刊论文(9)
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会议论文
ProvCaRe Semantic Provenance Knowledgebase: Evaluating Scientific Reproducibility of Research Studies.
ProvCaRe 语义起源知识库:评估研究的科学再现性。
DOI: --
发表时间: 2017
期刊: AMIA ... Annual Symposium proceedings. AMIA Symposium
影响因子: --
作者: [Valdez,Joshua, Kim,Matthew, Rueschman,Michael, Socrates,Vimig, Redline,Susan, Sahoo,SatyaS]
通讯作者: Sahoo,SatyaS
An Ontology-Enabled Natural Language Processing Pipeline for Provenance Metadata Extraction from Biomedical Text (Short Paper).
用于从生物医学文本中提取来源元数据的本体支持的自然语言处理管道(短论文)。
DOI: 10.1007/978-3-319-48472-3_43
发表时间: 2016
期刊: On the move to meaningful Internet systems ... : CoopIS, DOA, and ODBASE : Confederated International Conferences, CoopIS, DOA, and ODBASE ... proceedings. OTM Confederated International Conferences
影响因子: --
作者: [Valdez,Joshua, Rueschman,Michael, Kim,Matthew, Redline,Susan, Sahoo,SatyaS]
通讯作者: Sahoo,SatyaS
DOI: 10.1016/j.ijmedinf.2018.10.009
发表时间: 2019-01-01
期刊: INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS
影响因子: 4.9
作者: [Sahoo, Satya S., Valdez, Joshua, Redline, Susan]
通讯作者: Redline, Susan
Computing Functional Brain Connectivity in Neurological Disorders: Efficient Processing and Retrieval of Electrophysiological Signal Data
计算神经疾病中的功能性大脑连接:电生理信号数据的有效处理和检索
DOI: --
发表时间: 2019
期刊: AMIA Jt Summits Transl Sci Proc.
影响因子: --
作者: [Gershon, A, Devulapalli, P, Zonjy, B, Ghosh, K, Tatsuoka, C, Sahoo, SS]
通讯作者: Sahoo, SS
9
    A PROV standard-based data source agnostic provenance engine for Big Data analytics (Supplement)
    • 批准号:
      9243808
    • 项目类别:
    • 资助金额:
      $15.81万
    • 财政年份:
      2015
    • 负责人:
      Satya Sanket Sahoo
    • 依托单位:
    A PROV standard-based data source agnostic provenance engine for Big Data analytics
    • 批准号:
      8875904
    • 项目类别:
    • 资助金额:
      $30.44万
    • 财政年份:
      2015
    • 负责人:
      Satya Sanket Sahoo
    • 依托单位:
    海外基金